Author details

Full Name

Gerald W Dorn

Affiliation

ORCID

Career Start Year

1984

Papers

338

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36790900	Retooling the cardiac toolbox: the enduring legacy of Jeffrey Robbins.		2023
36416308	Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.	Human Molecular Genetics	2023
37582906	Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.		2023
37910431	A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.		2023
37644008	Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.		2023
37190097	Reversing Dysdynamism to Interrupt Mitochondrial Degeneration in Amyotrophic Lateral Sclerosis.		2023
37057625	Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac Muscle Remodeling.		2023
35326500	Predicting Mitochondrial Dynamic Behavior in Genetically Defined Neurodegenerative Diseases.	Cells	2022
35459212	Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.	Cell Death and Disease	2022
35759434	Neurohormonal connections with mitochondria in cardiomyopathy and other diseases.	American Journal of Physiology - Cell Physiology	2022
35646911	Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.	Frontiers in Cell and Developmental Biology	2022
36340925	Small molecules that enhance mitophagy to delay aging and neurodegeneration.		2022
36063101	Context-dependent mitochondrial modulation of diastolic sarcoplasmic reticular calcium release.	Cardiovascular Research	2022
35409362	Protein Kinase C (Pkc)-Î´ Mediates Arginine-Induced Glucagon Secretion in Pancreatic Î±-Cells.	International Journal of Molecular Sciences	2022
35534470	Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy.	Cell Death and Disease	2022
36507849	Mitochondrial Dysfunction and Pharmacodynamics of Mitofusin Activation in Murine Charcot-Marie-Tooth Disease Type 2A.		2022
35326504	Mitochondrial Phenotypes in Genetically Diverse Neurodegenerative Diseases and Their Response to Mitofusin Activation.	Cells	2022
34415150	Pharmacophore-Based Design of Phenyl-[hydroxycyclohexyl] Cycloalkyl-Carboxamide Mitofusin Activators with Improved Neuronal Activity.	Journal of Medicinal Chemistry	2021
34016983	Author Correction: TDP-43 and PINK1 mediate CHCHD10 mutation-induced defects in Drosophila and in vitro.	Nature Communications	2021
33463548	Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.	J Clin Invest	2021
33772006	TDP-43 and PINK1 mediate CHCHD10 mutation-induced defects in Drosophila and in vitro.	Nature Communications	2021
34193829	Correction: Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.	Cell Death and Disease	2021
33764162	Genomic Context Differs Between Human Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy.	J Am Heart Assoc	2021
33818493	Mitofusin activation enhances mitochondrial motility and promotes neuroregeneration in CMT2A.	Neural Regeneration Research	2021
33324000	Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.	Nat Neurosci	2021
32506913	Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases.	Journal of Medicinal Chemistry	2020
32304672	Mitofusins as mitochondrial anchors and tethers.	Journal of Molecular and Cellular Cardiology	2020
32240015	Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice.	Journal of Applied Physiology	2020
32406208	Targeting mitochondrial fusion and fission proteins for cardioprotection.	Journal of Cellular and Molecular Medicine	2020
32165499	The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca-NFATc1 axis.	Journal of Biological Chemistry	2020
32822172	Correction to "Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases".	Journal of Medicinal Chemistry	2020
33074106	Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.	eLife	2020
32733278	Mitofusin 2 Dysfunction and Disease in Mice and Men.	Frontiers in Physiology	2020
30882371	Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.	J Clin Invest	2019
31722203	NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8 T Cells.	Cell Reports	2019
31551592	Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.	Nat Neurosci	2019
30256725	Evolving Concepts of Mitochondrial Dynamics.	Annual Review of Physiology	2019
30540226	Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process.	Physiological Reviews	2019
31039007	Sex modulates hepatic mitochondrial adaptations to high-fat diet and physical activity.	American Journal of Physiology - Endocrinology and Metabolism	2019
31024341	Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.	Frontiers in Physiology	2019
31379586	Mitofusin 2 Is Essential for IP-Mediated SR/Mitochondria Metabolic Feedback in Ventricular Myocytes.	Frontiers in Physiology	2019
29495422	A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans.	J Pers Med	2018
30062822	Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1Î± and BNIP3-mediated mitophagy.	Journal of Physiology	2018
29969579	G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.	Journal of Molecular and Cellular Cardiology	2018
30467553	Cardiac-specific research platforms engender novel insights into mitochondrial dynamism.	Current Opinion in Physiology	2018
29674596	MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.	Science	2018
28289205	Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria?	Proceedings of the National Academy of Sciences of the United States of America	2017
28774384	Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.	J Am Coll Cardiol	2017
28904083	Assessing the effects of mitofusin 2 deficiency in the adult heart using 3D electron tomography.	Physiological Reports	2017
29107503	Abrogating Mitochondrial Dynamics in Mouse Hearts Accelerates Mitochondrial Senescence.		2017