Author details

Full Name

Stephen Eyre

Affiliation

ORCID

Career Start Year

1998

Papers

140

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36546557	Genome-wide association analysis identifies a susceptibility locus for sporadic vestibular schwannoma at 9p21.		2023
37287330	TYK2 as a novel therapeutic target in psoriasis.		2023
36810200	Pre-treatment calprotectin (MRP8/14) provides no added value to testing CRP alone in terms of predicting response to TNF inhibitors in rheumatoid arthritis in a post hoc analysis.		2023
36804406	Atopic Polygenic Risk Score Is Associated with Paradoxical Eczema Developing in Patients with Psoriasis Treated with Biologics.	J Invest Dermatol	2023
35094092	Association with HLA-DRÎ²1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis.	Hum Mol Genet	2022
36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Nat Genet	2022
35986704	Germline intergenic duplications at Xq26.1 underlie Bazex-DuprÃ©-Christol basal cell carcinoma susceptibility syndrome.	Br J Dermatol	2022
34433485	Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability.	Genome Biol	2021
33958779	Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.	Nat Genet	2021
33607115	Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.		2021
33106285	Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.	Ann Rheum Dis	2021
33188258	Characterisation of CD4+â¿¿T-cell subtypes using single cell RNA sequencing and the impact of cell number and sequencing depth.	Scientific Reports	2020
32196497	Exploring the overlap between rheumatoid arthritis susceptibility loci and long non-coding RNA annotations.	PLoS ONE	2020
32366252	Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.	BMC Biol	2020
31945409	Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.	Journal of Allergy and Clinical Immunology	2020
32271902	Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing.	Blood Adv	2020
32879318	Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis.	Nat Commun	2020
30530827	Genetics of rheumatoid arthritis: 2018 status.	Ann Rheum Dis	2019
29193869	CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification.	Arthritis Rheumatol	2018
30224649	Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.	Nat Genet	2018
28096457	The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort.	Rheumatology	2017
28569263	The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping.	Nature reviews. Rheumatology	2017
28109256	Optimisation of methods for bacterial skin microbiome investigation: primer selection and comparison of the 454 versus MiSeq platform.	BMC Microbiology	2017
27799070	Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.		2016
27111665	Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.	Arthritis Rheumatol	2016
26811024	One SNP at a Time: Moving beyond GWAS in Psoriasis.		2016
27151500	Development and application of a catchment scale pesticide fate and transport model for use in drinking water risk assessment.	Science of the Total Environment	2016
27109064	Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.	Scientific Reports	2016
26879349	Immunochip Analyses of Epistasis in Rheumatoid Arthritis Confirm Multiple Interactions within MHC and Suggest Novel Non-MHC Epistatic Signals.	Journal of Rheumatology	2016
27182969	A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.	Nat Genet	2016
27267163	Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.	Expert Opinion on Drug Discovery	2016
26895230	Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.	Arthritis and Rheumatology	2016
26814849	Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.	Arthritis and Rheumatology	2016
26386125	Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.	Ann Rheum Dis	2016
27861577	Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.	PLoS ONE	2016
24532676	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.	Ann Rheum Dis	2015
25817017	A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.	Am J Hum Genet	2015
25849893	TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.	PLoS One	2015
26053495	Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26312849	The skin microbiome in psoriatic arthritis: methodology development and pilot data.	Lancet, The	2015
26220137	Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26509058	Genetics of RA susceptibility, what comes next?	RMD Open	2015
26258845	Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.	Nat Genet	2015
26426166	Healthy Eating in Jamaica: The Cost Factor.	West Indian Medical Journal	2015
26667261	Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples.		2015
26616563	Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.	Nature Communications	2015
24092415	A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.	Ann Rheum Dis	2015
24656864	Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.	Am J Hum Genet	2014
25526303	Take your PICS: moving from GWAS to immune function.	Immunity	2014
24449572	Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.	Arthritis and Rheumatology	2014