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Author Details
Full Name
Rene Gonzalez
Affiliation
University of Colorado Anschutz Medical Campus
ORCID
Career Start Year
1990
Papers
165
H Index
64
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36378549
Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma.
Clin Cancer Res
2023
37345092
Introduction of a Polyethylene Glycol Linker Improves Uptake of <sup>67</sup>Cu-NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide in Melanoma.
Cancers (Basel)
2023
37140963
Effects of Polyethylene Glycol and 8-Aminooctanoic Acid Linkers on Melanoma Uptake of [<sup>99m</sup>Tc]Tc-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized α-MSH Peptides.
Bioconjug Chem
2023
34537899
Adjuvant Therapy for Stage III Melanoma Without Immediate Completion Lymph Node Dissection.
Ann Surg Oncol
2022
35475603
Novel Al<sup>18</sup>F-NOTA-Conjugated Lactam-Cyclized α-Melanocyte-Stimulating Hormone Peptides with Enhanced Melanoma Uptake.
Bioconjug Chem
2022
35486894
Novel <sup>64</sup>Cu-Labeled NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptides with Enhanced Tumor to Kidney Uptake Ratios.
Mol Pharm
2022
34762521
The Effect of Albumin-Binding Moiety on Tumor Targeting and Biodistribution Properties of <sup>67</sup>Ga-Labeled Albumin Binder-Conjugated Alpha-Melanocyte-Stimulating Hormone Peptides.
Cancer Biother Radiopharm
2022
34818112
Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma.
J Clin Oncol
2022
33234846
Safety and efficacy of combination nivolumab plus ipilimumab in patients with advanced melanoma: results from a North American expanded access program (CheckMate 218).
Melanoma Res
2021
34326162
Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma.
Cancer Discov
2021
33087417
Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft.
Mol Cancer Res
2021
32673170
Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629).
J Clin Oncol
2020
31732523
Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in <i>BRAF</i>-Mutant Melanoma.
Clin Cancer Res
2020
32062691
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors.
Cancer Chemother Pharmacol
2020
33141072
Facile preparation of a novel Ga-67-labeled NODAGA-conjugated lactam-cyclized alpha-MSH peptide at room temperature for melanoma targeting.
Bioorg Med Chem Lett
2020
33067454
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity.
Nat Commun
2020
32663011
Novel [<sup>99m</sup>Tc]-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized Alpha-MSH Peptide with Enhanced Melanoma Uptake and Reduced Renal Uptake.
Mol Pharm
2020
32708981
Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy.
Cancers (Basel)
2020
31171876
Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients.
Nat Med
2019
31644317
Melanoma-Targeting Property of Y-90-Labeled Lactam-Cyclized α-Melanocyte-Stimulating Hormone Peptide.
Cancer Biother Radiopharm
2019
31781510
IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients.
Front Oncol
2019
31602665
A nomogram to predict node positivity in patients with thin melanomas helps inform shared patient decision making.
J Surg Oncol
2019
31562797
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.
N Engl J Med
2019
30870269
Inflammatory side effects of BRAF and MEK inhibitors.
Melanoma Res
2019
30811280
Evaluation of Two Dosing Regimens for Nivolumab in Combination With Ipilimumab in Patients With Advanced Melanoma: Results From the Phase IIIb/IV CheckMate 511 Trial.
J Clin Oncol
2019
30777131
Therapy with high-dose Interleukin-2 (HD IL-2) in metastatic melanoma and renal cell carcinoma following PD1 or PDL1 inhibition.
J Immunother Cancer
2019
30763112
Evaluation of a Novel Pb-203-Labeled Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide for Melanoma Targeting.
Mol Pharm
2019
29054983
ALK Inhibitor Response in Melanomas Expressing <i>EML4-ALK</i> Fusions and Alternate <i>ALK</i> Isoforms.
Mol Cancer Ther
2018
29909499
Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.
J Neurooncol
2018
30121453
Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab.
Int Immunopharmacol
2018
30404861
[68]Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging.
Sci Transl Med
2018
30361170
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.
Lancet Oncol
2018
29402264
Performance of a prognostic 31-gene expression profile in an independent cohort of 523 cutaneous melanoma patients.
BMC Cancer
2018
28991513
Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib.
J Clin Oncol
2018
27993793
Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.
Ann Oncol
2017
28296713
Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.
Melanoma Res
2017
28961465
Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma.
Eur J Cancer
2017
29076950
Vemurafenib treatment for patients with locally advanced, unresectable stage IIIC or metastatic melanoma and activating exon 15 BRAF mutations other than V600E.
Melanoma Res
2017
28651159
Health-related quality of life results from the phase III CheckMate 067 study.
Eur J Cancer
2017
28891423
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma.
N Engl J Med
2017
28841387
Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials.
J Clin Oncol
2017
28889792
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.
N Engl J Med
2017
27864876
Kinase gene fusions in defined subsets of melanoma.
Pigment Cell Melanoma Res
2017
27916626
Impact of Sequencing Targeted Therapies With High-dose Interleukin-2 Immunotherapy: An Analysis of Outcome and Survival of Patients With Metastatic Renal Cell Carcinoma From an On-going Observational IL-2 Clinical Trial: PROCLAIM<sup>SM</sup>.
Clin Genitourin Cancer
2017
26811525
Overall Survival and Durable Responses in Patients With BRAF V600-Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib.
J Clin Oncol
2016
26440571
Correlation between early 18F-FDG PET/CT response to BRAF and MEK inhibition and survival in patients with BRAF-mutant metastatic melanoma.
Nucl Med Commun
2016
27660706
A retrospective analysis of High-Dose Interleukin-2 (HD IL-2) following Ipilimumab in metastatic melanoma.
J Immunother Cancer
2016
27714434
Contemporary experience with high-dose interleukin-2 therapy and impact on survival in patients with metastatic melanoma and metastatic renal cell carcinoma.
Cancer Immunol Immunother
2016
27496110
NCCN Guidelines Insights: Melanoma, Version 3.2016.
J Natl Compr Canc Netw
2016
26981242
Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study.
J Immunother Cancer
2016
1 - 50 of 165
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Bartosz Chmielowski
Jonsson Comprehensive Cancer Center, University of California Los Angeles
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Steven E Robinson
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Aik Choon Tan
Huntsman Cancer Institute, The University of Utah
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Dexiang Gao
University of Colorado Anschutz Medical Campus
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Peter Hersey
Co-authored papers
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Howard I Scher
Memorial Sloan Kettering Cancer Center
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Dave S B Hoon
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers
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Kimberly R Jordan
University of Colorado Anschutz Medical Campus
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Robert W Williams
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