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Author Details

Trevor F Moraes
University of Toronto, University Avenue
2000
64
28
PMIDPaper TitleJournal TitlePublished Year
36736884Anti-CRISPR Protein AcrIIC5 Inhibits CRISPR-Cas9 by Occupying the Target DNA Binding Pocket.J Mol Biol2023
37562569Dynamic players and intricate interactions: An integrated investigation of the Mla lipid transport system.J Biol Chem2023
36961851Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida.PLoS Pathog2023
37224531Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling.Nucleic Acids Res2023
34954237Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4<sub>Hpa</sub>.J Mol Biol2022
35475756Reconstitution of surface lipoprotein translocation through the Slam translocon.Elife2022
33412111A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.Mol Cell2021
33893302Inhibition of polar actin assembly by astral microtubules is required for cytokinesis.Nat Commun2021
34725337A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii.Nat Commun2021
34358566Actinobacillus utilizes a binding protein-dependent ABC transporter to acquire the active form of vitamin B<sub>6</sub>.J Biol Chem2021
33464171Determining the Odds of Difficult Airway Resolution Among Pediatric Patients: A Case Series.Otolaryngol Head Neck Surg2021
33277359The surface lipoproteins of gram-negative bacteria: Protectors and foragers in harsh environments.J Biol Chem2021
32366593Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of <i>Histophilus somni</i>.J Bacteriol2020
31998268Structural Basis for Evasion of Nutritional Immunity by the Pathogenic <i>Neisseriae</i>.Front Microbiol2020
32005666The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1).J Biol Chem2020
32659264Uev1A amino terminus stimulates poly-ubiquitin chain assembly and is required for NF-κB activation.Cell Signal2020
30837995Utility of Hybrid Transferrin Binding Protein Antigens for Protection Against Pathogenic Neisseria Species.Front Immunol2019
31243272Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.Nat Commun2019
29176613Global landscape of cell envelope protein complexes in Escherichia coli.Nat Biotechnol2018
29579694Translocation of lipoproteins to the surface of gram negative bacteria.Curr Opin Struct Biol2018
28620585Identification of a Large Family of Slam-Dependent Surface Lipoproteins in Gram-Negative Bacteria.Front Cell Infect Microbiol2017
28257520Lactoferrin binding protein B - a bi-functional bacterial receptor protein.PLoS Pathog2017
28276700Iron acquisition through the bacterial transferrin receptor.Crit Rev Biochem Mol Biol2017
28158534Neisserial surface lipoproteins: structure, function and biogenesis.Pathog Dis2017
29651895Structural biology of solute carrier (SLC) membrane transport proteins.Mol Membr Biol2017
29233895Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.mBio2017
27022027PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.J Biol Chem2016
26635355Effect of SLC26 anion transporter disease-causing mutations on the stability of the homologous STAS domain of E. coli DauA (YchM).Biochem J2016
27681475'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.Sci Rep2016
27382067Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly intermediates of the 30S subunit.Nucleic Acids Res2016
27572441Slam is an outer membrane protein that is required for the surface display of lipidated virulence factors in Neisseria.Nat Microbiol2016
26898305A method for measuring binding constants using unpurified in vivo biotinylated ligands.Anal Biochem2016
25547790Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities.Infect Immun2015
26439635Solute carriers keep on rockin'.Nat Struct Mol Biol2015
26621472Structural Aspects of Bacterial Outer Membrane Protein Assembly.Adv Exp Med Biol2015
26295949Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.PLoS Pathog2015
26282243The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.Nat Commun2015
25800619Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system.Microbiologyopen2015
23733950Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression.Proc Natl Acad Sci U S A2013
24121512A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters.J Biol Chem2013
24266357Bacterial receptors for host transferrin and lactoferrin: molecular mechanisms and role in host-microbe interactions.Future Microbiol2013
22369045Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin.Biochem J2012
22705263Membrane transport metabolons.Biochim Biophys Acta2012
22343719The structural basis of transferrin sequestration by transferrin-binding protein B.Nat Struct Mol Biol2012
21487007Conserved interaction between transferrin and transferrin-binding proteins from porcine pathogens.J Biol Chem2011
22069313Anchor peptide of transferrin-binding protein B is required for interaction with transferrin-binding protein A.J Biol Chem2011
21297163Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB.J Biol Chem2011
20799927The role of vicinal tyrosine residues in the function of Haemophilus influenzae ferric-binding protein A.Biochem J2010
21070944Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.Structure2010
19056346Biological significance of structural differences between two highly conserved Ubc variants.Biochem Biophys Res Commun2009
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Collaborators

Institut National de la Recherche Scientifique (INRS), Universite du Quebec
Co-authored papers 15
University of Toronto, University Avenue
Co-authored papers 9
University of Toronto
Co-authored papers 9
Child Health Research Foundation
Co-authored papers 9
The University of British Columbia
Co-authored papers 5
University of Toronto, University Avenue
Co-authored papers 5
University of Calgary, 0 Hospital Drive NW
Co-authored papers 4
Boston University School of Medicine, Boston University
Co-authored papers 2
Human Health Therapeutics Research Centre, National Research Council Canada
Co-authored papers 2
University of Regina
Co-authored papers 2
College Street, University of Toronto
Co-authored papers 2
University of Ottawa
Co-authored papers 1
University of Regina
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
University of California at San Diego
Co-authored papers 1
Center for the Study of Biological Complexity, Virginia Commonwealth University
Co-authored papers 1
University of Toronto, University Avenue
Co-authored papers 1
University of California at San Diego
Co-authored papers 1
University of Saskatchewan
Co-authored papers 1
University of Regina
Co-authored papers 1
University of Toronto
Co-authored papers 1
Beihang University
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Northern British Columbia
Co-authored papers 1
Uppsala University
Co-authored papers 1
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
Ottawa Institute of Systems Biology, University of Ottawa, Carleton University
Co-authored papers 1
University of Toronto
Co-authored papers 1
Department of Biology and Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 1