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Author Details

Monte M Winslow
Stanford University School of Medicine
2002
82
44
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36635501Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.Nat Cell Biol2023
37783795Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis.Nat Cell Biol2023
37828026Oncogenic context shapes the fitness landscape of tumor suppression.Nat Commun2023
37291262Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.Nat Methods2023
37277208High-Throughput Identification, Modeling, and Analysis of Cancer Driver Genes In Vivo.Cold Spring Harb Perspect Med2023
37138029Dissecting metastasis using preclinical models and methods.Nat Rev Cancer2023
36995340Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages.J Exp Med2023
36778226Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma.bioRxiv2023
36640300A multiplexed in vivo approach to identify driver genes in small cell lung cancer.Cell Rep2023
35228570LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer.Nat Commun2022
35425962Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.Cancer Res2022
35752172Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles.Mol Cell2022
36160047A new system for multiplexed mosaic analysis of gene function in the mouse.Cell Rep Methods2022
35252550Tumor suppressor pathways shape EGFR-driven lung tumor progression and response to treatment.Mol Cell Oncol2022
33296145Mechanisms of small cell lung cancer metastasis.EMBO Mol Med2021
33854239The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.Nature2021
33619540Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects.Nucleic Acids Res2021
33707235Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response <i>In Vivo</i>.Cancer Discov2021
33608386A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer.Cancer Discov2021
34818551Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis.Cell Rep2021
34301766<i>miR-200</i> deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts.Genes Dev2021
34215621Quantitative <i>In Vivo</i> Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma.Cancer Res2021
34341533LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.Nat Cell Biol2021
33239425Altered Mitochondria Functionality Defines a Metastatic Cell State in Lung Cancer and Creates an Exploitable Vulnerability.Cancer Res2021
32238925CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.Nature2020
33025906A versatile system to record cell-cell interactions.Elife2020
33157015Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.Mol Cell2020
31350327An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation.Cancer Discov2019
29610476Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.Nat Genet2018
30002193Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.Mol Cancer Res2018
30228296Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.Sci Rep2018
30228179Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.Cancer Discov2018
30267031Towards quantitative and multiplexed in vivo functional cancer genomics.Nat Rev Genet2018
30327497Publisher Correction: Towards quantitative and multiplexed in vivo functional cancer genomics.Nat Rev Genet2018
28790031BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.Cancer Discov2017
28191885Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.Nat Med2017
29233960Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.Nat Commun2017
28652369Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.Proc Natl Acad Sci U S A2017
28530655A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.Nat Methods2017
27374332Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.Cell2016
27617390An in vivo multiplexed small-molecule screening platform.Nat Methods2016
27150038An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.Cancer Cell2016
27294525CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.J Clin Invest2016
24317514Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma.Oncogene2015
26244988Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.PLoS Genet2015
26537451Recombinase-based conditional and reversible gene regulation via XTR alleles.Nat Commun2015
26178787Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.Genes Dev2015
26039341Design of Protease Activated Optical Contrast Agents That Exploit a Latent Lysosomotropic Effect for Use in Fluorescence-Guided Surgery.ACS Chem Biol2015
24305048HMGA2 functions as a competing endogenous RNA to promote lung cancer progression.Nature2014
25042806An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.Mol Cell2014
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Collaborators

Tyler Jacks
Co-authored papers 14
Dmitri A Petrov
Stanford University
Co-authored papers 12
Christopher W Murray
Stanford University School of Medicine
Co-authored papers 12
David M Feldser
Co-authored papers 7
Julien Sage
Department of Pediatrics Stanford University Stanford California USA.
Co-authored papers 6
Caroline C Kim
Tufts Medical Center
Co-authored papers 5
Christina S Kong
Stanford University School of Medicine
Co-authored papers 5
Charles A Whittaker
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Co-authored papers 4
William J Greenleaf
Stanford University
Co-authored papers 4
Michael C Bassik
Stanford University Medical Center
Co-authored papers 4
Peter K Jackson
Stanford University School of Medicine, Center for Clinical Sciences Research
Co-authored papers 4
Christina Curtis
Stanford University School of Medicine
Co-authored papers 4
E Alejandro Sweet-Cordero
University of California San Francisco
Co-authored papers 4
Anshul Kundaje
Stanford University.
Co-authored papers 4
Jose A Seoane
Universidade da Coruna
Co-authored papers 4
Peyton G Greenside
Co-authored papers 3
Alexandros P Drainas
Stanford University School of Medicine
Co-authored papers 3
Seung K Kim
Stanford University School of Medicine
Co-authored papers 3
Myung Chang Lee
Stanford University
Co-authored papers 3
Matthew Meyerson
Broad Institute
Co-authored papers 2
Marcus R Kelly
Stanford University School of Medicine
Co-authored papers 2
Charles Swanton
Francis Crick Institute
Co-authored papers 2
Richard O Hynes
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Co-authored papers 2
Jeffrey M Granja
Stanford University School of Medicine
Co-authored papers 2
Janos Demeter
Stanford University School of Medicine, Center for Clinical Sciences Research
Co-authored papers 2
Charles M Rudin
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Yan Ting Shue
Stanford University
Co-authored papers 2
Andrea C Chaikovsky
Stanford University
Co-authored papers 2
Julie H Ko
Stanford University
Co-authored papers 2
Leanne C Sayles
Co-authored papers 2
Release 1.2