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Author Details

Rod Bremner
University of Toronto
1990
95
35
PMIDPaper TitleJournal TitlePublished Year
37812728Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning.Proc Natl Acad Sci U S A2023
37552601Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses.Cell Rep2023
35165102Targeting the Ubiquitin-Proteasome System Using the UBA1 Inhibitor TAK-243 is a Potential Therapeutic Strategy for Small-Cell Lung Cancer.Clin Cancer Res2022
35544541Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application.PLoS One2022
35505181Mapping transgene insertion sites reveals the α-Cre transgene expression in both developing retina and olfactory neurons.Commun Biol2022
36002557Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2.Sci Rep2022
36108220Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.Cancer Discov2022
35235778CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities.Cell Rep2022
35023164Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.EMBO J2022
34001180Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods.Virol J2021
33526784A glucose meter interface for point-of-care gene circuit-based diagnostics.Nat Commun2021
33658502A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2.Nat Commun2021
34859143Simplifying cancer: binary pan-cancer superclasses stratified by opposite YAP/TEAD effects.Mol Cell Oncol2021
34494680Photoreceptor nanotubes mediate the in vivo exchange of intracellular material.EMBO J2021
34430805InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes.iScience2021
34632420Lentiviral-mediated ectopic expression of YAP and TAZ in YAP<sup>off</sup> cancer cell lines.STAR Protoc2021
34270926Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.Cancer Cell2021
32175920Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration.J Clin Invest2020
32572160Functional genomics identifies new synergistic therapies for retinoblastoma.Oncogene2020
32878923Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina.Development2020
32923640The NEMP family supports metazoan fertility and nuclear envelope stiffness.Sci Adv2020
32123578Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy.Cell Death Discov2020
32386599Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.Dev Cell2020
30853441FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling.Dev Cell2019
31613797Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.JCI Insight2019
31451763Extracellular phosphorylation drives the formation of neuronal circuitry.Nat Chem Biol2019
29511172Rb is required for retinal angiogenesis and lamination.Cell Death Dis2018
29748386Frequent interferon regulatory factor 1 (IRF1) binding at remote elements without histone modification.J Biol Chem2018
27819669A CDK2 activity signature predicts outcome in CDK2-low cancers.Oncogene2017
28274199Properties of STAT1 and IRF1 enhancers and the influence of SNPs.BMC Mol Biol2017
28288457Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition.J Innate Immun2017
26030458Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways.PLoS One2015
26432891Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.J Immunol2015
25862816Polycomb Repressive Complex 2 Confers BRG1 Dependency on the CIITA Locus.J Immunol2015
25950466Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors.Cell Death Dis2015
24339342Induction of the ganglion cell differentiation program in human retinal progenitors before cell cycle exit.Dev Dyn2014
25252972Cancer: The origin of human retinoblastoma.Nature2014
25127134Modifying lipid rafts promotes regeneration and functional recovery.Cell Rep2014
23359713Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins.Proc Natl Acad Sci U S A2013
24107252A rapid and efficient method to purify proteins at replication forks under native conditions.Biotechniques2013
23558950E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3.Cell Death Differ2013
22286767Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.Oncogene2012
22940085The double-stranded RNA-binding protein Staufen 2 regulates eye size.Mol Cell Neurosci2012
22837015Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.Dev Dyn2012
21711866Subretinal gene delivery using helper-dependent adenoviral vectors.Cell Biosci2011
19588467Association of reading disabilities with regions marked by acetylated H3 histones in KIAA0319.Am J Med Genet B Neuropsychiatr Genet2010
20719946Histone deacetylases and the nuclear receptor corepressor regulate lytic-latent switch gene 50 in murine gammaherpesvirus 68-infected macrophages.J Virol2010
20610631Cyclins, Cdks, E2f, Skp2, and more at the first international RB Tumor Suppressor Meeting.Cancer Res2010
20565244CDKN1C (p57KIP2) mRNA expression in human retinoblastomas.Ophthalmic Genet2010
20014120Maximizing functional photoreceptor differentiation from adult human retinal stem cells.Stem Cells2010
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Collaborators

Marek Pacal
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 13
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 9
Brenda L Gallie
The Eye Cancer Clinic, Princess Margaret Cancer Centre, Hospital for Sick Children
Co-authored papers 7
Eldad Zacksenhaus
University of Toronto
Co-authored papers 6
Tony Mazzulli
Mount Sinai Health System and University Health Network
Co-authored papers 4
Zuyao Ni
University of Toronto, College Street
Co-authored papers 4
James R Woodgett
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 4
Daniel Schramek
University of Toronto
Co-authored papers 3
Zhe Jiang
Toronto General Research Institute, University Health Network, 67 College Street
Co-authored papers 3
Lea Harrington
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 2
Gary D Bader
University of Toronto
Co-authored papers 2
Donald J Zack
Johns Hopkins University School of Medicine
Co-authored papers 2
Neil Winegarden
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Frederick A Dick
Western University
Co-authored papers 2
Derek van der Kooy
University of Toronto
Co-authored papers 2
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 2
Sandy D Der
Toronto General Research Institute, University Health Network
Co-authored papers 2
Joan E Wither
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 2
Jason Moffat
University of Toronto
Co-authored papers 1
Alison L Martens
Co-authored papers 1
Hong Han
Hangzhou City University
Co-authored papers 1
Michel L Tremblay
Co-authored papers 1
Dax Torti
Ontario Institute for Cancer Research
Co-authored papers 1
Loyal A Goff
Johns Hopkins University School of Medicine
Co-authored papers 1
Lawrence E Heisler
Ontario Institute for Cancer Research
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
David W Andrews
Sunnybrook Research Institute, University of Toronto
Co-authored papers 1
Mark A Watson
Washington University School of Medicine
Co-authored papers 1
Mark Takahashi
York University
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Minggao Liang
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Release 1.2