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Author Details

Karim C El Kasmi
Boehringer Ingelheim Pharma GmbH & Co. KG
1998
67
35
PMIDPaper TitleJournal TitlePublished Year
36227799Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.Am J Respir Cell Mol Biol2023
37647292Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition.PLoS One2023
37072070Application of human iPSC-derived macrophages in a miniaturized high-content-imaging-based efferocytosis assay.SLAS Discov2023
36848082Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis.Hepatol Commun2023
36459066Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis.J Cell Biol2023
34387888Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.Hepatology2022
35503656CD206+ tumor-associated macrophages cross-present tumor antigen and drive antitumor immunity.JCI Insight2022
35763349IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD.JCI Insight2022
35058211Automation enables high-throughput and reproducible single-cell transcriptomics library preparation.SLAS Technol2022
35027468Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.Life Sci Alliance2022
34664730Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice.JPEN J Parenter Enteral Nutr2022
33175574Hepatic thermal injury promotes colorectal cancer engraftment in C57/black 6 mice.Am J Physiol Cell Physiol2021
33868271Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.Front Immunol2021
33558616IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice.Commun Biol2021
34310734NF-κB Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis.Hepatology2021
34001904Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.Nat Commun2021
34162546Lactate and IL6 define separable paths of inflammatory metabolic adaptation.Sci Adv2021
31263097Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.Nat Commun2019
31560857Redistribution of EC-SOD resolves bleomycin-induced inflammation via increased apoptosis of recruited alveolar macrophages.FASEB J2019
28637353Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.Antioxid Redox Signal2018
30319651Immunotolerant p50/NFκB Signaling and Attenuated Hepatic IFNβ Expression Increases Neonatal Sensitivity to Endotoxemia.Front Immunol2018
30367045The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.Nat Commun2018
29643332Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis.Nat Commun2018
29507905Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice.Hepatol Commun2018
27805412Superoxide Dismutase 3 R213G Single-Nucleotide Polymorphism Blocks Murine Bleomycin-Induced Fibrosis and Promotes Resolution of Inflammation.Am J Respir Cell Mol Biol2017
28500078A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.J Immunol2017
29047090Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension.Adv Exp Med Biol2017
28972001Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.Circulation2017
28830617Cancer-promoting mechanisms of tumor-associated neutrophils.Am J Surg2017
27780972Developmental origins of NAFLD: a womb with a clue.Nat Rev Gastroenterol Hepatol2017
26699943Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.Am J Respir Cell Mol Biol2016
27562971Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.Circulation2016
25416383The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.Am J Physiol Lung Cell Mol Physiol2015
26454572Contribution of metabolic reprogramming to macrophage plasticity and function.Semin Immunol2015
26342031Endotoxemia Induces IκBβ/NF-κB-Dependent Endothelin-1 Expression in Hepatic Macrophages.J Immunol2015
25930027Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.J Appl Physiol (1985)2015
24041791Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein.J Infect Dis2014
25329595Specific microbiome changes in a mouse model of parenteral nutrition associated liver injury and intestinal inflammation.PLoS One2014
24928992Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.J Immunol2014
24705404Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates.Diabetes2014
23240585Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome.Antioxid Redox Signal2013
24107776Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition-associated liver disease.Sci Transl Med2013
23637937Role of arginase 1 from myeloid cells in th2-dominated lung inflammation.PLoS One2013
23460643Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.J Biol Chem2013
23216413The adventitia: essential regulator of vascular wall structure and function.Annu Rev Physiol2013
22120983Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury.Hepatology2012
22558514Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.Pulm Circ2012
21813768Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.J Immunol2011
19201841LAG-3 regulates plasmacytoid dendritic cell homeostasis.J Immunol2009
19360123Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis.PLoS Pathog2009
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Collaborators

Aimee L Anderson
University of Colorado School of Medicine
Co-authored papers 13
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 12
Ronald J Sokol
Digestive Health Institute, Children's Hospital Colorado
Co-authored papers 11
Michael W Devereaux
University of Colorado School of Medicine
Co-authored papers 9
Amber M Smith
University of California san francisco
Co-authored papers 7
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Swati Ghosh
University of Colorado School of Medicine
Co-authored papers 4
David J Orlicky
University of Colorado School of Medicine
Co-authored papers 4
Colin T Shearn
University of Colorado School of Medicine
Co-authored papers 3
Clyde J Wright
University of Colorado School of Medicine and Children's Hospital Colorado
Co-authored papers 3
Mark A Lovell
University of Kentucky
Co-authored papers 2
Richard D Schulick
University of Colorado School of Medicine
Co-authored papers 2
William J Janssen
Co-authored papers 2
Daniel C Link
Washington University School of Medicine
Co-authored papers 1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Kevin L Grove
Novo Nordisk Research Center Seattle
Co-authored papers 1
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Katherine A Fitzgerald
Co-authored papers 1
Florent Ginhoux
Co-authored papers 1
Bin Zhou
The Central Hospital of Shaoyang
Co-authored papers 1
Kjetil Ask
McMaster University
Co-authored papers 1
Release 1.2