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Author Details
Full Name
Jeffery G Saven
Affiliation
University of Pennsylvania
ORCID
Career Start Year
1996
Papers
93
H Index
36
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36988077
Genetic Fusion of Thermoresponsive Polypeptides with UCST-type Behavior Mediates 1D Assembly of Coiled-Coil Bundlemers.
Angew Chem Int Ed Engl
2023
37874177
Thermoresponsive Coiled-Coil Peptide-Polymer Grafts.
Bioconjug Chem
2023
34749446
Colloid-like solution behavior of computationally designed coiled coil bundlemers.
J Colloid Interface Sci
2022
35312288
Computational Design of Homotetrameric Peptide Bundle Variants Spanning a Wide Range of Charge States.
Biomacromolecules
2022
35209027
Computational Design of Single-Peptide Nanocages with Nanoparticle Templating.
Molecules
2022
34029045
Nanofibers Produced by Electrospinning of Ultrarigid Polymer Rods Made from Designed Peptide Bundlemers.
ACS Appl Mater Interfaces
2021
33679256
The C-terminus of the mu opioid receptor is critical in G-protein interaction as demonstrated by a novel graphene biosensor.
IEEE Sens J
2021
33689866
Recombinant expression of computationally designed peptide-bundlemers in Escherichia coli.
J Biotechnol
2021
34709798
Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials.
Chem Rev
2021
34757723
Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization.
Biochemistry
2021
34152652
Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines.
Proteins
2021
31588852
Characterization of an engineered water-soluble variant of the full-length human mu opioid receptor.
J Biomol Struct Dyn
2020
31738361
Polyelectrolyte character of rigid rod peptide bundlemer chains constructed via hierarchical self-assembly.
Soft Matter
2019
31666724
Polymers with controlled assembly and rigidity made with click-functional peptide bundles.
Nature
2019
31828182
Water Soluble G-protein Coupled Receptor Enabled Biosensors.
Transl Perioper Pain Med
2019
29634231
All-Electronic Quantification of Neuropeptide-Receptor Interaction Using a Bias-Free Functionalized Graphene Microelectrode.
ACS Nano
2018
30051936
A protein-protein host-guest complex: Thermostable ferritin encapsulating positively supercharged green fluorescent protein.
Protein Sci
2018
29923575
Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles.
Soft Matter
2018
30299090
Nanotubes, Plates, and Needles: Pathway-Dependent Self-Assembly of Computationally Designed Peptides.
Biomacromolecules
2018
26626969
Quantifying the effect of ionic screening with protein-decorated graphene transistors.
Biosens Bioelectron
2017
28397914
Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection.
Org Biomol Chem
2017
29148741
Controlling Association and Separation of Gold Nanoparticles with Computationally Designed Zinc-Coordinating Proteins.
J Am Chem Soc
2017
28970912
Structural-functional analysis of engineered protein-nanoparticle assemblies using graphene microelectrodes.
Chem Sci
2017
28612484
pH Sensing Properties of Flexible, Bias-Free Graphene Microelectrodes in Complex Fluids: From Phosphate Buffer Solution to Human Serum.
Small
2017
28639674
Transition from disordered aggregates to ordered lattices: kinetic control of the assembly of a computationally designed peptide.
Org Biomol Chem
2017
28682599
Thermophilic Ferritin 24mer Assembly and Nanoparticle Encapsulation Modulated by Interdimer Electrostatic Repulsion.
Biochemistry
2017
26840013
Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein.
J Am Chem Soc
2016
27626071
Computationally designed peptides for self-assembly of nanostructured lattices.
Sci Adv
2016
27227361
Scalable Production of Molybdenum Disulfide Based Biosensors.
ACS Nano
2016
24365264
Molecular interactions between general anesthetics and the 5HT2B receptor.
J Biomol Struct Dyn
2015
29861959
Xe affinities of water-soluble cryptophanes and the role of confined water.
Chem Sci
2015
26262433
Observing Changes in the Structure and Oligomerization State of a Helical Protein Dimer Using Solid-State Nanopores.
ACS Nano
2015
25829447
Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors.
Sci Signal
2015
24742304
Scalable production of highly sensitive nanosensors based on graphene functionalized with a designed G protein-coupled receptor.
Nano Lett
2014
25251904
Engineering complementary hydrophobic interactions to control β-hairpin peptide self-assembly, network branching, and hydrogel properties.
Biomacromolecules
2014
25031097
Tribute to James L. Skinner.
J Phys Chem B
2014
24835677
Characterization of a computationally designed water-soluble human μ-opioid receptor variant using available structural information.
Anesthesiology
2014
23799068
A computationally designed water-soluble variant of a G-protein-coupled receptor: the human mu opioid receptor.
PLoS One
2013
24070370
Single-handed helical wrapping of single-walled carbon nanotubes by chiral, ionic, semiconducting polymers.
J Am Chem Soc
2013
23941695
Origins of the helical wrapping of phenyleneethynylene polymers about single-walled carbon nanotubes.
J Phys Chem B
2013
23931685
Computational de novo design and characterization of a protein that selectively binds a highly hyperpolarizable abiological chromophore.
J Am Chem Soc
2013
22155685
NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.
Biochim Biophys Acta
2012
24527268
Human μ Opioid Receptor Models with Evaluation of the Accuracy Using the Crystal Structure of the Murine μ Opioid Receptor.
J Anesth Clin Res
2012
22538812
Computational design of a protein crystal.
Proc Natl Acad Sci U S A
2012
22579257
Knowledge-based potential for positioning membrane-associated structures and assessing residue-specific energetic contributions.
Structure
2012
22244752
Computational design of membrane proteins.
Structure
2012
22392968
Binding site and affinity prediction of general anesthetics to protein targets using docking.
Anesth Analg
2012
22025496
Opioid binding sites in human serum albumin.
Anesth Analg
2012
21271707
Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane.
J Org Chem
2011
21911811
Computational protein design to reengineer stromal cell-derived factor-1α generates an effective and translatable angiogenic polypeptide analog.
Circulation
2011
1 - 50 of 93
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row(s) 1 - 30 of 30
Collaborators
William F DeGrado
Department of Pharmaceutical Chemistry, University of California san francisco
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Roderic G Eckenhoff
University of Pennsylvania, Perelman School of Medicine
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2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers
1
Camden M Driggers
Co-authored papers
1
Luigi Di Costanzo
University of Naples Federico II
Co-authored papers
1
Pei Tang
Sichuan University
Co-authored papers
1
Daniel J Rader
Co-authored papers
1
Patricia C Babbitt
University of California san francisco
Co-authored papers
1
David S Roos
University of Pennsylvania
Co-authored papers
1
Xi-Ping Huang
University of North Carolina School of Medicine
Co-authored papers
1
Yan Xu
Nanjing Drum Tower Hospital
Co-authored papers
1
Feng Chen
Bayer Healthcare Pharmaceuticals
Co-authored papers
1
Bryan L Roth
UNC Chapel Hill School of Medicine
Co-authored papers
1
Yi-Ping Joseph Woo
Stanford University
Co-authored papers
1
Mark E Peterson
University of California-San Francisco
Co-authored papers
1
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