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Author Details

Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
1992
323
106
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38087889Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation.Adv Sci (Weinh)2024
38087889Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation.Adv Sci (Weinh)2024
36394953Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.J Clin Invest2023
35608632Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy.Neuro Oncol2023
35980802Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation.Autophagy2023
36394953Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.J Clin Invest2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
37980347LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation.Nat Commun2023
37979586EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.Mol Cell2023
37623431Reply to "Targeting cholesterol homeostasis through inhibiting: An Achilles' heel for glioblastoma?"Neuro Oncol2023
36521011Novel INHAT repressor drives glioblastoma growth by promoting ribosomal DNA transcription in glioma stem cells.Neuro Oncol2023
37280108Glioblastoma Stem Cell Targeting Peptide Isolated Through Phage Display Binds Cadherin 2.Stem Cells2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
36649564Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.Cancer Discov2023
36581779ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.J Neurooncol2023
37398280Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants.bioRxiv2023
37198486Lysine catabolism reprograms tumour immunity through histone crotonylation.Nature2023
37326042Watching the clock in glioblastoma.Neuro Oncol2023
37439870Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.Clin Cancer Res2023
36934350Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.Neuro Oncol2023
36795488Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting.JCI Insight2023
36732025WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.Genes Dev2023
36849558A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.Nat Cell Biol2023
36595671Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.Proc Natl Acad Sci U S A2023
37623431Reply to "Targeting cholesterol homeostasis through inhibiting: An Achilles' heel for glioblastoma?"Neuro Oncol2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
37980347LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation.Nat Commun2023
37979586EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.Mol Cell2023
35608632Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy.Neuro Oncol2023
37326042Watching the clock in glioblastoma.Neuro Oncol2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37280108Glioblastoma Stem Cell Targeting Peptide Isolated Through Phage Display Binds Cadherin 2.Stem Cells2023
37439870Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.Clin Cancer Res2023
37398280Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants.bioRxiv2023
37198486Lysine catabolism reprograms tumour immunity through histone crotonylation.Nature2023
36521011Novel INHAT repressor drives glioblastoma growth by promoting ribosomal DNA transcription in glioma stem cells.Neuro Oncol2023
36849558A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.Nat Cell Biol2023
36649564Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.Cancer Discov2023
36581779ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.J Neurooncol2023
36934350Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.Neuro Oncol2023
36732025WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.Genes Dev2023
36795488Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting.JCI Insight2023
36595671Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.Proc Natl Acad Sci U S A2023
35980802Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation.Autophagy2023
34615656Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.Cancer Discov2022
35659339PDGF signaling inhibits mitophagy in glioblastoma stem cells through N<sup>6</sup>-methyladenosine.Dev Cell2022
35841593β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.Cancer Res2022
35710946Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity.Nat Rev Cancer2022
35393416CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity.Nat Commun2022
36097162SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.Nat Commun2022
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Collaborators

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St Jude Children's Research Hospital
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The Hospital for Sick Children
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Lerner Research Institute, Cleveland Clinic
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McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 8
Lerner Research Institute, Cleveland Clinic
Co-authored papers 7
University of California San Diego
Co-authored papers 7
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 7
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
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Hospital for Sick Children
Co-authored papers 6
University of Chicago
Co-authored papers 5
University of Pittsburgh School of Medicine
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Rhode Island Hospital
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University of Wollongong
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