Author details

Full Name

Jian'an Luan

Affiliation

ORCID

Career Start Year

2000

Papers

224

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36658113	Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.	Nat Commun	2023
37749248	Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.	Nat Genet	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37398003	Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.	medRxiv	2023
36693378	Loci for insulin processing and secretion provide insight into type 2 diabetes risk.	Am J Hum Genet	2023
36991119	An atlas of genetic scores to predict multi-omic traits.	Nature	2023
37503126	Understanding the genetic complexity of puberty timing across the allele frequency spectrum.	medRxiv	2023
34875679	Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.	Journal of Clinical Endocrinology and Metabolism	2022
36153617	Features of effective staff training programmes within school-based interventions targeting student activity behaviour: a systematic review and meta-analysis.	International Journal of Behavioral Nutrition and Physical Activity	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35104449	Genetic Associations and Architecture of Asthma-COPD Overlap.	Chest	2022
34480422	The genomics of heart failure: design and rationale of the HERMES consortium.	ESC Heart Fail	2021
34070864	Prepubertal Dietary and Plasma Phospholipid Fatty Acids Related to Puberty Timing: Longitudinal Cohort and Mendelian Randomization Analyses.	Nutrients	2021
33531486	Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection.	Nat Commun	2021
34270325	Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.	Circ Genom Precis Med	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33414548	A cross-platform approach identifies genetic regulators of human metabolism and health.	Nat Genet	2021
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
34461734	Utility of Genetically Predicted Lp(a) (Lipoprotein [a]) and ApoB Levels for Cardiovascular Risk Assessment.	Circ Genom Precis Med	2021
34819519	Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.	Nature Communications	2021
34648354	Mapping the proteo-genomic convergence of human diseases.	Science	2021
30617275	Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.	Mol Psychiatry	2020
32180562	Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort.	Mol Metab	2020
33096487	Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes.	eBioMedicine	2020
33188205	Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.	Sci Data	2020
32916155	Corrigendum to "Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort" [Molecular Metabolism 34 (2020) 85-96].	Mol Metab	2020
32637948	Genetic architecture of host proteins interacting with SARS-CoV-2.	bioRxiv	2020
33230300	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2020
33328453	Genetic architecture of host proteins involved in SARS-CoV-2 infection.	Nat Commun	2020
31145760	Regional fat depot masses are influenced by protein-coding gene variants.	PLoS ONE	2019
29988085	Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.	Mol Psychiatry	2019
31088856	Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.	Diabetes	2019
31491410	Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.	Am J Hum Genet	2019
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
30804560	New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.	Nat Genet	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31002796	Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.	Cell	2019
31345923	Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.	BMJ	2019
31151930	MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.	EBioMedicine	2019
29358691	Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.	Nat Commun	2018
30390057	Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.	Nat Genet	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
30388399	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.	Am J Hum Genet	2018
30429575	Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018
30575882	Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.	JAMA	2018
30326043	Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes.	JAMA Cardiol	2018
30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Nat Genet	2018
30224653	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018