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Author Details
Full Name
Clifford P Brangwynne
Affiliation
Lewis-Sigler Institute for Integrative Genomics, Princeton University
ORCID
Career Start Year
1999
Papers
81
H Index
47
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37837191
Condensate interfaces can accelerate protein aggregation.
Biophys J
2024
36801820
An FGF timer for zygotic genome activation.
Genes Dev
2023
37788668
A disordered region controls cBAF activity via condensation and partner recruitment.
Cell
2023
37683610
Viscoelasticity and advective flow of RNA underlies nucleolar form and function.
Mol Cell
2023
37925738
Erratum: Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin [Phys. Rev. Lett. 126, 258102 (2021)].
Phys Rev Lett
2023
37073403
Size distributions of intracellular condensates reflect competition between coalescence and nucleation.
Nat Phys
2023
37471224
Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions.
Cell Rep
2023
35077681
Compartmentalization of telomeres through DNA-scaffolded phase separation.
Dev Cell
2022
35540725
The mechanobiology of nuclear phase separation.
APL Bioeng
2022
36071192
Capillary forces generated by biomolecular condensates.
Nature
2022
32873929
The nucleolus as a multiphase liquid condensate.
Nat Rev Mol Cell Biol
2021
33890572
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation.
Elife
2021
33692345
Properties of repression condensates in living Ciona embryos.
Nat Commun
2021
33723425
TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis.
Nat Cell Biol
2021
34552246
Nucleation landscape of biomolecular condensates.
Nature
2021
34598580
Phase separation vs aggregation behavior for model disordered proteins.
J Chem Phys
2021
34620850
Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction.
Nat Commun
2021
34106828
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics.
Elife
2021
34302807
Interaction of spindle assembly factor TPX2 with importins-α/β inhibits protein phase separation.
J Biol Chem
2021
34241518
Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin.
Phys Rev Lett
2021
32405004
Composition-dependent thermodynamics of intracellular phase separation.
Nature
2020
32087632
Model for disordered proteins with strongly sequence-dependent liquid phase behavior.
J Chem Phys
2020
31974233
Can phase separation buffer cellular noise?
Science
2020
32929202
Nucleated transcriptional condensates amplify gene expression.
Nat Cell Biol
2020
32302570
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Cell
2020
30633909
Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds.
Cell
2019
31754043
The liquid nucleome - phase transitions in the nucleus at a glance.
J Cell Sci
2019
31792412
Probing and engineering liquid-phase organelles.
Nat Biotechnol
2019
31562479
Voices in methods development.
Nat Methods
2019
31399547
Controlling the material properties and rRNA processing function of the nucleolus using light.
Proc Natl Acad Sci U S A
2019
31199001
Phase separation in biology and disease-a symposium report.
Ann N Y Acad Sci
2019
31540706
Quantifying Dynamics in Phase-Separated Condensates Using Fluorescence Recovery after Photobleaching.
Biophys J
2019
30849377
Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome.
Cell
2019
29313527
Physical principles of intracellular organization via active and passive phase transitions.
Rep Prog Phys
2018
29859829
Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli.
Cell Syst
2018
30500535
Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome.
Cell
2018
30500534
Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds.
Cell
2018
28041848
Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets.
Cell
2017
28183799
Farming and public goods production in <i>Caenorhabditis elegans</i> populations.
Proc Natl Acad Sci U S A
2017
28935776
Liquid phase condensation in cell physiology and disease.
Science
2017
29064502
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles.
Nat Chem
2017
28562583
Neurodegenerative disease: RNA repeats put a freeze on cells.
Nature
2017
27212236
Coexisting Liquid Phases Underlie Nucleolar Subcompartments.
Cell
2016
27705784
Hierarchical Size Scaling during Multicellular Growth and Development.
Cell Rep
2016
27791212
Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics.
Soft Matter
2016
27362225
Cell division: A sticky problem for chromosomes.
Nature
2016
25702583
Inverse size scaling of the nucleolus by a concentration-dependent phase transition.
Curr Biol
2015
26438852
Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion.
Proc Natl Acad Sci U S A
2015
26351690
RNA transcription modulates phase transition-driven nuclear body assembly.
Proc Natl Acad Sci U S A
2015
26651288
Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration.
Dev Cell
2015
1 - 50 of 81
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