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Author Details

David Spetzler
2006
57
19
PMIDPaper TitleJournal TitlePublished Year
37034762Multi-omic characterization reveals a distinct molecular landscape in young-onset pancreatic cancer.2023
37853341Pan-tumor survey of ROS1 fusions detected by next-generation RNA and whole transcriptome sequencing.BMC Cancer2023
37944590Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.Nat Med2023
37944072Multiomic Characterization Reveals a Distinct Molecular Landscape in Young-Onset Pancreatic Cancer.2023
36993741Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.Res Sq2023
36681091Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.Lancet Oncol2023
37516008Pan-tumor survey of RET fusions as detected by next-generation RNA sequencing identified RET fusion positive colorectal carcinoma as a unique molecular subset.2023
37291277Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target.2023
35302596Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma.Clinical Cancer Research2022
35366570FOLFOXIRI and bevacizumab in patients with early-onset metastatic colorectal cancer. A pooled analysis of TRIBE and TRIBE2 studies.European Journal of Cancer2022
35918812Discoidin Domain Receptor-Driven Gene Signatures as Markers of Patient Response to Anti-PD-L1 Immune Checkpoint Therapy.J Natl Cancer Inst2022
36395141Somatic 9p24.1 alterations in HPV<sup>-</sup> head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.Proc Natl Acad Sci U S A2022
36557020<i>BRCA1/2</i> Reversion Mutations in Patients Treated with Poly ADP-Ribose Polymerase (PARP) Inhibitors or Platinum Agents.Medicina (Kaunas)2022
34469533Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications.Journal of the National Cancer Institute2022
34365081Tumour mutational burden, microsatellite instability, and actionable alterations in metastatic colorectal cancer: Next-generation sequencing results of TRIBE2 study.European Journal of Cancer2021
33707526Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes.Scientific Reports2021
33798656Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS-MAPK pathway and TP53 as potential predictors of immunotherapy efficacy.Ann Oncol2021
34167745Response to "The need for validation of MI GPSai in patients with CUP: Comment on: "Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type" by J Abraham et al."Translational Oncology2021
33952700Immune evasion in HPV<sup>-</sup> head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.Proc Natl Acad Sci U S A2021
33465745Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type.Transl Oncol2021
33293373Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer.Clin Cancer Res2021
34562615Predicted Immunogenicity of CDK12 Biallelic Loss-of-Function Tumors Varies across Cancer Types.J Mol Diagn2021
34589990Identification of Novel <i>CDH1-NRG2</i>α and <i>F11R-NRG2α</i> Fusions in NSCLC Plus Additional Novel <i>NRG2α</i> Fusions in Other Solid Tumors by Whole Transcriptome Sequencing.JTO Clin Res Rep2020
32201861Primary CNS lymphoma commonly expresses immune response biomarkers.Neurooncol Adv2020
32197944Molecular Profiling of the Metaplastic Spindle Cell Carcinoma of the Breast Reveals Potentially Targetable Biomarkers.Clin Breast Cancer2020
31989173ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes.Nucleic Acids Research2020
32644297Population bias in somatic measurement of microsatellite instability status.Cancer Medicine2020
33426529A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram.Neurooncol Adv2020
30930163Translocation of a Cell Surface Spliceosomal Complex Induces Alternative Splicing Events and Lymphoma Cell Necrosis.Cell Chemical Biology2019
31712784Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma.Clin Oncol Res2019
31209843Immunohistochemistry-Enabled Precision Medicine.Cancer Treatment and Research2019
29846894Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design.J Neurooncol2018
29923182Profiles of brain metastases: Prioritization of therapeutic targets.Int J Cancer2018
29869738Rethinking medulloblastoma from a targeted therapeutics perspective.J Neurooncol2018
29867023KIAA0100 Modulates Cancer Cell Aggression Behavior of MDA-MB-231 through Microtubule and Heat Shock Proteins.Cancers2018
29572535Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes.Nat Commun2018
29718398Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas.J Neuropathol Exp Neurol2018
29760063Elastic coupling power stroke mechanism of the F-ATPase molecular motor.Proceedings of the National Academy of Sciences of the United States of America2018
29436178Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients.Cancer Medicine2018
29696079Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion.Journal of Extracellular Vesicles2018
28218293Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach.Sci Rep2017
28596308Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.Science2017
28371827Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy.Neuro Oncol2017
29487694Ependymomas overexpress chemoresistance and DNA repair-related proteins.Oncotarget2017
26942886Impact of molecular profiling on overall survival of patients with advanced ovarian cancer.Oncotarget2016
26933808Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.Oncotarget2016
27370400Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies.Neuro Oncol2016
21809213Microsecond resolution of single-molecule rotation catalyzed by molecular motors.Methods in Molecular Biology2011
21037553Direct observation of stepped proteolipid ring rotation in E. coli F⿿F⿁-ATP synthase.EMBO Journal2010
20023738Solving the fully-connected 15-city TSP using probabilistic DNA computing.Integrative Biology (United Kingdom)2009
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