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Author Details

Benjamin J Blencowe
University of Toronto
1989
178
77
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36597481Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors.Heliyon2023
38065061Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors.Mol Cell2023
37059883Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2.Nat Cell Biol2023
37237245Publisher Correction: Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2.Nat Cell Biol2023
37002329RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific.Sci Rep2023
36959352Global detection of human variants and isoforms by deep proteome sequencing.Nat Biotechnol2023
34901782SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.iScience2022
35914530Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.Mol Cell2022
35914531Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1.Mol Cell2022
35182477Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns.Mol Cell2022
33417854Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2021
33658502A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2.Nat Commun2021
34675241Publisher Correction: Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention.Nat Commun2021
34508259Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline.Nat Protoc2021
34083519Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention.Nat Commun2021
33436550Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity.Nat Commun2021
31559909Neuronal-specific microexon splicing of <i>TAF1</i> mRNA is directly regulated by SRRM4/nSR100.RNA Biol2020
31999954Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.Mol Cell2020
32069328An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.PLoS Pathog2020
33259812Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2020
32249828Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform.Nat Biotechnol2020
32492419A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.Cell Rep2020
32535349Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder.Curr Opin Genet Dev2020
30698747ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development.Nucleic Acids Res2019
31626751Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution.Mol Cell2019
31448565Differential contribution of steady-state RNA and active transcription in chromatin organization.EMBO Rep2019
30988016A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes.EMBO J2019
30833759A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons.Nat Ecol Evol2019
31112699The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo.Dev Cell2019
30679363Toward unrestricted use of public genomic data.Science2019
30390048Autism spectrum disorder: insights into convergent mechanisms from transcriptomics.Nat Rev Genet2019
29592814QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data.Genome Biol2018
29995847Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.Nature2018
30220560Efficient and Accurate Quantitative Profiling of Alternative Splicing Patterns of Any Complexity on a Laptop.Mol Cell2018
30388412Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.Mol Cell2018
29625061Orchestrating Ribosomal Subunit Coordination to Control Stem Cell Fate.Cell Stem Cell2018
28709000Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing.Cell2017
28483376The Relationship between Alternative Splicing and Proteomic Complexity.Trends Biochem Sci2017
28329680Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.Cell Rep2017
28188528LUMIER: A Discovery Tool for Mammalian Protein Interaction Networks.Methods Mol Biol2017
28157508Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.Mol Cell2017
28122580Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation.Retrovirology2017
28855263An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.Genome Res2017
26700805SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination.Nature2016
27984743Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.Mol Cell2016
27820807The ribosome-engaged landscape of alternative splicing.Nat Struct Mol Biol2016
27791185Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.Proc Natl Acad Sci U S A2016
27732849MECP2 Is Post-transcriptionally Regulated during Human Neurodevelopment by Combinatorial Action of RNA-Binding Proteins and miRNAs.Cell Rep2016
27919067Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.Nature2016
27365209The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation.RNA2016
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Collaborators

University of Toronto
Co-authored papers 35
University of Toronto
Co-authored papers 22
University of Toronto
Co-authored papers 19
Sloan Kettering Institute
Co-authored papers 18
University of Toronto
Co-authored papers 13
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 11
University of Toronto
Co-authored papers 10
College Street, University of Toronto
Co-authored papers 10
University of Toronto
Co-authored papers 9
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 9
Hangzhou City University
Co-authored papers 8
University of Toronto
Co-authored papers 8
Queen's University
Co-authored papers 8
Co-authored papers 8
University of Dundee
Co-authored papers 7
Co-authored papers 6
Nanjing Agricultural University
Co-authored papers 6
Boston University School of Medicine, Boston University
Co-authored papers 6
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 4
University of Perugia
Co-authored papers 4
University of Minnesota - Twin Cities
Co-authored papers 4
University of California los angeles
Co-authored papers 4
a division of The Scripps Research Institute La Jolla
Co-authored papers 4
College Street, University of Toronto
Co-authored papers 4
Co-authored papers 3
University of Toronto
Co-authored papers 3
The University of Hong Kong
Co-authored papers 3
University of Toronto
Co-authored papers 3
The Hospital for Sick Children
Co-authored papers 3
Co-authored papers 3