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Author Details

Ram??n Campos-Olivas
Spanish National Cancer Research Centre (CNIO)
1995
65
25
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36354735The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner.EMBO J2023
37139660DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling.Cancer Commun (Lond)2023
34958836Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis.J Hepatol2022
36507540Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging.Front Med (Lausanne)2022
36055235Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.Mol Cell2022
35022249Structural basis of Nrd1-Nab3 heterodimerization.Life Sci Alliance2022
34135321Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.Nat Commun2021
34099838Urine NMR-based TB metabolic fingerprinting for the diagnosis of TB in children.Sci Rep2021
33339845Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker.Sci Rep2020
28792888Structural basis for interdomain communication in SHIP2 providing high phosphatase activity.Elife2017
28356389Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.J Exp Med2017
28973465The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.Nucleic Acids Res2017
28548080Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.Nat Commun2017
27087366Conformational Selection and Induced Fit Mechanisms in the Binding of an Anticancer Drug to the c-Src Kinase.Sci Rep2016
26553526Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.ChemMedChem2016
27721423p21<sup>Cip1</sup> plays a critical role in the physiological adaptation to fasting through activation of PPARα.Sci Rep2016
27505673Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms.Cancer Cell2016
27166371Stabilization of i-motif structures by 2'-β-fluorination of DNA.Nucleic Acids Res2016
26169224The N-terminal domain of MuB protein has striking structural similarity to DNA-binding domains and mediates MuB filament-filament interactions.J Struct Biol2015
26322680AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.Nat Cell Biol2015
26286748Alternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses.J Biol Chem2015
26365176MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.Cell Metab2015
24837572Discovery of selective ligands for telomeric RNA G-quadruplexes (TERRA) through 19F-NMR based fragment screening.ACS Chem Biol2014
25004980BuD, a helix-loop-helix DNA-binding domain for genome modification.Acta Crystallogr D Biol Crystallogr2014
25043816A switch from white to brown fat increases energy expenditure in cancer-associated cachexia.Cell Metab2014
22940919Autoinhibition of TBCB regulates EB1-mediated microtubule dynamics.Cell Mol Life Sci2013
24115468Backbone FC-H···O hydrogen bonds in 2'F-substituted nucleic acids.Angew Chem Int Ed Engl2013
24194925The effect of antitumor glycosides on glioma cells and tissues as studied by proton HR-MAS NMR spectroscopy.PLoS One2013
22798499The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.Nucleic Acids Res2012
23226505Specific synthesis of neurostatin and gangliosides O-acetylated in the outer sialic acids using a sialate transferase.PLoS One2012
23139781Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR.PLoS One2012
20809889NMR screening and hit validation in fragment based drug discovery.Curr Top Med Chem2011
26598273A Simple Mechanism Underlying the Effect of Protecting Osmolytes on Protein Folding.J Chem Theory Comput2011
21523440Backbone assignment of the tyrosine kinase Src catalytic domain in complex with imatinib.Biomol NMR Assign2011
21364740Reduced stability and increased dynamics in the human proliferating cell nuclear antigen (PCNA) relative to the yeast homolog.PLoS One2011
20460379Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase.J Biol Chem2010
20812746Helical and flat structures from chiral dendronized rectangular oligo(phenylene ethynylene)s.Org Lett2010
19636889NMR assignment and secondary structure of human growth arrest and DNA damage alpha protein (Gadd45 alpha).Biomol NMR Assign2008
17036161Backbone assignment of the 98 kDa homotrimeric yeast PCNA ring.J Biomol NMR2007
19636876Backbone assignment of human proliferating cell nuclear antigen.Biomol NMR Assign2007
17275023Solution structure, divalent metal and DNA binding of the endonuclease domain from the replication initiation protein from porcine circovirus 2.J Mol Biol2007
17472345Solution structure of the endonuclease domain from the master replication initiator protein of the nanovirus faba bean necrotic yellows virus and comparison with the corresponding geminivirus and circovirus structures.Biochemistry2007
170437451H, 13C, and 15N NMR assignment of the master Rep protein nuclease domain from the nanovirus FBNYV.J Biomol NMR2007
166367551H, 13C, and 15N NMR assignment of the Rep protein nuclease domain from the porcine circovirus PCV2.J Biomol NMR2006
17105190pH-Dependent conformational stability of the ribotoxin alpha-sarcin and four active site charge substitution variants.Biochemistry2006
15152082Solution structure of the hypothetical protein Mth677 from Methanobacterium thermoautotrophicum: a novel alpha+beta fold.Protein Sci2004
145127371H, 13C and 15N backbone assignments of the pheromone binding protein from the silk moth Antheraea polyphemus (ApolPBP).J Biomol NMR2003
12062409Placement of 19F into the center of GB1: effects on structure and stability.FEBS Lett2002
12130667The structure of a replication initiator unites diverse aspects of nucleic acid metabolism.Proc Natl Acad Sci U S A2002
12522295Backbone dynamics of the cytotoxic ribonuclease alpha-sarcin by 15N NMR relaxation methods.J Biomol NMR2002
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Collaborators

University of Pittsburgh
Co-authored papers 8
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 3
Spanish National Cancer Research Centre-CNIO
Co-authored papers 2
CNRS, Universite de Strasbourg
Co-authored papers 1
Albert Einstein College of Medicine
Co-authored papers 1
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
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University of California San Francisco
Co-authored papers 1
Center for Applied Medical Research (CIMA)
Co-authored papers 1
Centre de recherche sur le cancer de l'Universite Laval, Universite Laval
Co-authored papers 1
Josep Carreras Leukaemia Research Institute (IJC)
Co-authored papers 1
Spanish National Cancer Research Center (CNIO)
Co-authored papers 1
University of Toronto
Co-authored papers 1
University of Toronto
Co-authored papers 1
Englander Institute for Precision Medicine
Co-authored papers 1