Author details

Full Name

Nicholas K Foreman

Affiliation

ORCID

Career Start Year

1988

Papers

223

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37934854	Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.	Neuro Oncol	2024
36602034	Thromboembolic toxicity observed with concurrent trametinib and lenalidomide therapy.		2023
35831712	Pediatric pineal region masses: a single-center experience over 25Â years.	Child's Nervous System	2023
36215273	Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.	Neuro-Oncology	2023
36440550	PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem.	Journal of Neuropathology and Experimental Neurology	2023
37878192	Genetic predictors of neurocognitive outcomes in survivors of pediatric brain tumors.		2023
37694144	Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.		2023
37770931	Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.		2023
37609195	Genetic Predictors of Neurocognitive Outcomes in Survivors of Pediatric Brain Tumors.		2023
36808285	Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: Safety, efficacy, biomarker, and pharmacokinetics-CheckMate 908.	Neuro Oncol	2023
36747867	Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy.	bioRxiv	2023
37246777	Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study.	Neuro Oncol	2023
37041276	Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas.		2023
34477871	A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.	Neuro Oncol	2022
35901835	Response assessment in paediatric intracranial ependymoma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.	Lancet Oncol	2022
35814855	Radiation Therapy for Young Children Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant for Primary Brain Tumors.	Adv Radiat Oncol	2022
34077540	Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.	Neuro Oncol	2022
35029673	Outcomes after first relapse of children with intracranial ependymoma treated on the second l'Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) protocol.	Neuro-Oncology	2022
35179215	Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.	Int J Oncol	2022
34545084	Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.	Nat Commun	2021
33749791	NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.	J Neuropathol Exp Neurol	2021
33585982	Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).	Acta Neuropathol	2021
33684222	Long-term outcomes from the second l'Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) protocol.	Neuro-Oncology	2021
34046693	Targeting fibroblast growth factor receptors to combat aggressive ependymoma.	Acta Neuropathol	2021
34613815	Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.	Sci Transl Med	2021
32614133	A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups.	Pediatr Blood Cancer	2020
32268092	Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.	Cell Rep	2020
31969682	Correction: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.	Oncogene	2020
31595628	Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.	Pediatr Blood Cancer	2020
31844250	BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.	Oncogene	2020
32014486	In vitro benchmarking of NF-ÎºB inhibitors.	Eur J Pharmacol	2020
32180106	Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.	J Neurooncol	2020
32404202	Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets.	Acta Neuropathol Commun	2020
32930721	ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients.	Journal of Neuropathology and Experimental Neurology	2020
33037266	Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images.	Sci Rep	2020
32642682	Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine.	Neurooncol Adv	2020
33086074	Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.	Cell Rep	2020
33063010	Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas.	Neurooncol Adv	2020
32783945	Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.	Cell Rep	2020
32506370	Retrospective analysis of combination carboplatin and vinblastine for pediatric low-grade glioma.	Journal of Neuro-Oncology	2020
31497533	Targeting IL-6 Is a Potential Treatment for Primary Cystic Craniopharyngioma.	Frontiers in Oncology	2019
30230537	Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.	Int J Cancer	2019
30626740	Combined functional genomic and chemical screens identify SETD8 as a therapeutic target in MYC-driven medulloblastoma.	JCI Insight	2019
30811284	Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma.	J Clin Oncol	2019
31276586	Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.	Neuro Oncol	2019
30848081	Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors.	Pediatric Blood and Cancer	2019
31367784	Bevacizumab in the treatment of radiation injury for children with central nervous system tumors.	Child's Nervous System	2019
30783209	Safety and feasibility of outpatient autologous stem cell transplantation in pediatric patients with primary central nervous system tumors.	Bone Marrow Transplantation	2019
31515514	Effect of early-stage autophagy inhibition in BRAF<sup>V600E</sup> autophagy-dependent brain tumor cells.	Cell Death Dis	2019
29285586	Intracranial Ewing sarcoma: four pediatric examples.	Child's Nervous System	2018