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Author Details
Full Name
Rasmus Hartmann-Petersen
Affiliation
University of Copenhagen
ORCID
Career Start Year
1998
Papers
141
H Index
43
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36758042
Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qPCR assay.
PLoS One
2023
37160462
Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components.
Cell Mol Life Sci
2023
37443362
Discovering functionally important sites in proteins.
Nat Commun
2023
36976271
Rare Catechol-<i>O</i>-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets.
Biochemistry
2023
37463013
Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin-ligase Dma1 in vitro.
Protein Sci
2023
37292969
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay.
bioRxiv
2023
36609589
HSP70-binding motifs function as protein quality control degrons.
Cell Mol Life Sci
2023
36434153
Lynch syndrome, molecular mechanisms and variant classification.
Br J Cancer
2023
36495918
Prediction of Quality-control Degradation Signals in Yeast Proteins.
J Mol Biol
2023
36863450
The moonlighting of RAD23 in DNA repair and protein degradation.
Biochim Biophys Acta Gene Regul Mech
2023
35974206
A context-dependent and disordered ubiquitin-binding motif.
Cell Mol Life Sci
2022
35700725
Disease-linked mutations cause exposure of a protein quality control degron.
Structure
2022
36400171
14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes.
Diabetes Res Clin Pract
2022
36481666
Conserved degronome features governing quality control associated proteolysis.
Nat Commun
2022
36350035
How phosphorylation impacts intrinsically disordered proteins and their function.
Essays Biochem
2022
34166445
A new sensitive and fast assay for the detection of EGFR mutations in liquid biopsies.
PLoS One
2021
33779753
Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance.
Mol Biol Evol
2021
33886538
Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition.
PLoS Genet
2021
33914734
Mapping the degradation pathway of a disease-linked aspartoacylase variant.
PLoS Genet
2021
34750429
Adipose MDM2 regulates systemic insulin sensitivity.
Sci Rep
2021
34272906
The disordered PCI-binding human proteins CSNAP and DSS1 have diverged in structure and function.
Protein Sci
2021
31449985
Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome.
Eur J Med Genet
2020
33137092
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation.
PLoS Genet
2020
32759676
Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome.
Biomolecules
2020
32142608
Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water.
ACS Synth Biol
2020
29470691
Even effect of milk protein and carbohydrate intake but no further effect of heavy resistance exercise on myofibrillar protein synthesis in older men.
Eur J Nutr
2019
31697235
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
Elife
2019
31213625
Water dynamics in MCF-7 breast cancer cells: a neutron scattering descriptive study.
Sci Rep
2019
30712981
Biophysical and Mechanistic Models for Disease-Causing Protein Variants.
Trends Biochem Sci
2019
30635086
Protein stability and degradation in health and disease.
Adv Protein Chem Struct Biol
2019
30648773
Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations.
Hum Mutat
2019
29111377
Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function.
Neurochem Int
2018
30230310
Random Mutagenesis Analysis of the Influenza A M2 Proton Channel Reveals Novel Resistance Mutants.
Biochemistry
2018
30355493
Expanded Interactome of the Intrinsically Disordered Protein Dss1.
Cell Rep
2018
28065793
Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites.
Neurochem Int
2017
28245241
Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists.
PLoS One
2017
28422960
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations.
PLoS Genet
2017
28779490
Blocking protein quality control to counter hereditary cancers.
Genes Chromosomes Cancer
2017
28765280
The exocyst subunit Sec3 is regulated by a protein quality control pathway.
J Biol Chem
2017
27966061
UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1.
Cell Stress Chaperones
2017
26944332
DSS1/Sem1, a Multifunctional and Intrinsically Disordered Protein.
Trends Biochem Sci
2016
26507541
Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice.
J Nutr Biochem
2016
26578713
p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.
Am J Physiol Endocrinol Metab
2016
27613054
High-Throughput siRNA Screening Applied to the Ubiquitin-Proteasome System.
Methods Mol Biol
2016
27497779
No effect of anti-inflammatory medication on postprandial and postexercise muscle protein synthesis in elderly men with slightly elevated systemic inflammation.
Exp Gerontol
2016
26966660
Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.
PeerJ
2016
26709791
The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove.
Front Biosci (Landmark Ed)
2016
26708109
Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators.
Eur J Med Chem
2016
26703188
The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects.
Prog Lipid Res
2016
27026084
Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice.
Am J Physiol Endocrinol Metab
2016
1 - 50 of 141
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Anette P Gjesing
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S??ren Brunak
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