Author details

Full Name

Rosa Luna

Affiliation

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36827184	DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops.	Cell Rep	2023
31390568	Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability.	Cell Reports	2019
32493765	The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops.	Cold Spring Harbor Symposia on Quantitative Biology	2019
29074626	Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genomeÂ instability.	EMBO Journal	2017
27035147	Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening.	PLoS Genetics	2016
25092323	Oxysterols are agonist ligands of RORÎ³t and drive Th17 cell differentiation.	Proceedings of the National Academy of Sciences of the United States of America	2014
25294824	A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions.	Nucleic Acids Research	2014
23260350	Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.	Bioorganic and Medicinal Chemistry Letters	2013
23762389	R-loop mediated transcription-associated recombination in trf4Î¿ mutants reveals new links between RNA surveillance and genome integrity.	PLoS ONE	2013
22207203	New clues to understand the role of THO and other functionally related factors in mRNP biogenesis.		2012
22144908	Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.	PLoS Genetics	2011
21478823	A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors.	EMBO Journal	2011
21329510	Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers.	BMC Cancer	2011
21680710	Nab2 functions in the metabolism of RNA driven by polymerases II and III.	Molecular Biology of the Cell	2011
22174696	Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.	PLoS Genet	2011
20148946	The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt.		2010
19229139	Transcription at the proximity of the nuclear pore: a role for the THP1-SAC3-SUS1-CDC31 (THSC) complex.	RNA Biology	2009
18682986	A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants.	Molecular Genetics and Genomics	2008
17960421	Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.	Mol Genet Genomics	2008
18667528	The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.	Molecular Biology of the Cell	2008
18427828	Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus.	Chromosoma	2008
17525531	Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.	Cell Cycle	2007
17571346	Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.	Nature	2007
16738307	Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants.	Molecular and Cellular Biology	2006
16908536	An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.	Molecular and Cellular Biology	2006
15949445	Interdependence between transcription and mRNP processing and export, and its impact on genetic stability.	Molecular Cell	2005
15899964	Direct isolation and identification of promoters in the human genome.	Genome Res	2005
12702719	Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.	J Biol Chem	2003
12355087	Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis.	Nature Genetics	2002
12093753	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.	EMBO Journal	2002
11829501	Characterization of two highly similar Rad51 homologs of Physcomitrella patens.	Journal of Molecular Biology	2002
10656688	Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product.	Oncogene	2000
9247314	Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase.	Oncogene	1997
8980494	Structure of the dehydrin tas14 gene of tomato and its developmental and environmental regulation in transgenic tobacco.	Plant Molecular Biology	1996