Skip to Main Content

Author Details

Peter A Kiener
BioKien LLC
1976
122
59
PMIDPaper TitleJournal TitlePublished Year
34584159Peptide-HLA-based immunotherapeutics platforms for direct modulation of antigen-specific T cells.Sci Rep2021
31964784CUE-101, a Novel E7-pHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies.Clin Cancer Res2020
23575268Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.MAbs2013
21881594Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis.Genes Immun2012
22750228Targeting the junction of CɿmX and ɿ-migis for the specific depletion of mIgE-expressing B cells.Mol Immunol2012
22864384Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.MAbs2012
20971830IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways.Am J Respir Crit Care Med2011
21803750Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway.Ann Rheum Dis2011
21902688A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.Br J Haematol2011
20042593Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.J Immunol2010
20843364Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice.Respir Res2010
20513525MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.J Allergy Clin Immunol2010
20513521Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma.J Allergy Clin Immunol2010
20619294Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.Antiviral Res2010
18835037Combination of rituximab with blinatumomab (MT103/MEDI-538), a T cell-engaging CD19-/CD3-bispecific antibody, for highly efficient lysis of human B lymphoma cells.Leuk Res2009
20948567Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus.Hum Genomics Proteomics2009
19699208The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators.J Mol Biol2009
19342971Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA.J Immunother2009
19484140Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors.Neoplasia2009
19479852Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.Arthritis Rheum2009
19568280An audience with...Peter Kiener.Nat Rev Drug Discov2009
17990791Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab.Curr Top Microbiol Immunol2008
18802121YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages.J Immunol2008
19010911A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo.Cancer Res2008
19008400Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus.J Gen Virol2008
18980502Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis.J Infect Dis2008
18475307Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha.Mol Med2008
18648529Type I interferon: potential therapeutic target for psoriasis?PLoS One2008
18389897The prophylactic administration of a monoclonal antibody against human metapneumovirus attenuates viral disease and airways hyperresponsiveness in mice.Antivir Ther2008
17417641Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.Nat Immunol2007
17968926Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis.Arthritis Rheum2007
17961258Motavizumab, a neutralizing anti-Respiratory Syncytial Virus (Rsv) monoclonal antibody significantly modifies the local and systemic cytokine responses induced by Rsv in the mouse model.Virol J2007
18003958A chitinase-like protein in the lung and circulation of patients with severe asthma.N Engl J Med2007
18049331Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class.J Immunother2007
17362988Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract.J Mol Biol2007
17440108Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct.Cancer Res2007
16873237Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo.J Virol2006
17172415Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin.Mol Cancer Ther2006
16800841Serum levels of sCD137 (4-1BB) ligand are prognostic factors for progression in acute myeloid leukemia but not in non-Hodgkin's lymphoma.Eur J Haematol2006
16793771Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn).J Biol Chem2006
15907931Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization.J Mol Biol2005
16251314Comparative effects of two neutralizing anti-respiratory syncytial virus (RSV) monoclonal antibodies in the RSV murine model: time versus potency.Antimicrob Agents Chemother2005
15061197Alterations in Fas (CD 95/Apo-1) and Fas ligand (CD178) expression in acute promyelocytic leukemia during treatment with ATRA.Leuk Lymphoma2004
15302161Analysis of human and primate CD2 molecules by protein sequence and epitope mapping with anti-human CD2 antibodies.Mol Immunol2004
15297418EphA2 expression is associated with aggressive features in ovarian carcinoma.Clin Cancer Res2004
14977833PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma.Clin Cancer Res2004
15125967Identification of purine inhibitors of phosphodiesterase 7 (PDE7).Bioorg Med Chem Lett2004
15101715Serum levels of CD137 ligand and CD178 are prognostic factors for progression of myelodysplastic syndrome.Leuk Lymphoma2004
12747783Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties.J Med Chem2003
14633720Differential EphA2 epitope display on normal versus malignant cells.Cancer Res2003
  • 1 - 50 of 122

Recommended Authors

BioLineRx Ltd
Career Start Year 1999
Number of shared co-authors 0
Columbia University
Career Start Year 1993
Number of shared co-authors 0
West Virginia University School of Medicine
Career Start Year 1992
Number of shared co-authors 1
Stockholm University
Career Start Year 1989
Number of shared co-authors 0
Weill Cornell School of Medicine
Career Start Year 1988
Number of shared co-authors 1
Center for Cancer Research, National Cancer Institute.
Career Start Year 1988
Number of shared co-authors 0
Helen Wills Neuroscience Institute, University of California berkeley
Career Start Year 1988
Number of shared co-authors 0
Translational Health Science and Technology Institute
Career Start Year 1987
Number of shared co-authors 0
University of Vienna
Career Start Year 1985
Number of shared co-authors 0
Stanford University School of Medicine
Career Start Year 1985
Number of shared co-authors 0
Hoag Memorial Hospital Presbyterian
Career Start Year 1983
Number of shared co-authors 3
Universite Cote d'Azur, INSERM U5
Career Start Year 1982
Number of shared co-authors 1
University of Texas Southwestern Medical Center
Career Start Year 1981
Number of shared co-authors 0
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Career Start Year 1981
Number of shared co-authors 1
St. Anna Children's Hospital, Medical University of Vienna
Career Start Year 1980
Number of shared co-authors 0
Center for Computational and Integrative Biology, Massachusetts General Hospital
Career Start Year 1980
Number of shared co-authors 0
University of Nebraska Medical Center
Career Start Year 1980
Number of shared co-authors 0
8Benaroya Research Institute
Career Start Year 1978
Number of shared co-authors 0
University of California san francisco
Career Start Year 1978
Number of shared co-authors 0
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1977
Number of shared co-authors 1
Lund University
Career Start Year 1977
Number of shared co-authors 0
National Cancer Institute
Career Start Year 1976
Number of shared co-authors 0
Center for Future Medical Research, Tokyo Medical University
Career Start Year 1975
Number of shared co-authors 0
Center for Cancer Research, National Cancer Institute
Career Start Year 1975
Number of shared co-authors 0
Genentech Inc.
Career Start Year 1974
Number of shared co-authors 0
Massachusetts General Hospital
Career Start Year 1973
Number of shared co-authors 1
Princess Margaret Cancer Centre, University Health Network
Career Start Year 1970
Number of shared co-authors 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1969
Number of shared co-authors 0
RIKEN Center for Integrative Medical Sciences (IMS)
Career Start Year 1966
Number of shared co-authors 0
University of British Columbia
Career Start Year 1965
Number of shared co-authors 0

Collaborators

MedImmune LLC
Co-authored papers 7
University of Washington
Co-authored papers 6
Cellular Biomedicine Group Inc.
Co-authored papers 6
Oncology R&D Unit
Co-authored papers 5
Translational and Clinical Data Sciences
Co-authored papers 5
Corbus Pharmaceuticals Holdings
Co-authored papers 5
MedImmune LLC
Co-authored papers 4
University of Oxford
Co-authored papers 4
Massachusetts General Hospital
Co-authored papers 3
St. Jude Children's Research Hospital
Co-authored papers 3
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Boston Children's Hospital, Seoul National University, Seoul National University Hospital
Co-authored papers 2
Brigham Women's Hospital, Harvard Medical School
Co-authored papers 2
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Georgia Cancer Center, Medical College of Georgia
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Brigham and Women's Hospital Department of Neurology, and Harvard Medical School
Co-authored papers 1
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
University of Massachusetts School of Medicine
Co-authored papers 1
Co-authored papers 1
Institute of Psychology, Jagiellonian University
Co-authored papers 1
Harbin Medical University
Co-authored papers 1
Taussig Cancer Institute, Cleveland Clinic
Co-authored papers 1
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
VA Boston Healthcare System
Co-authored papers 1
The Brady Urological Institute, Johns Hopkins University School of Medicine
Co-authored papers 1