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Author Details

John J Stegeman
Woods Hole Oceanographic Institution
1971
231
61
PMIDPaper TitleJournal TitlePublished Year
36969097The Minderoo-Monaco Commission on Plastics and Human Health.Ann Glob Health2023
37841805Correction: The Minderoo-Monaco Commission on Plastics and Human Health.Ann Glob Health2023
37209461Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.J Inorg Biochem2023
36009001Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity.Biomolecules2022
35801640Metabolic arsenal of giant viruses: Host hijack or self-use?Elife2022
36072831Announcing the Minderoo - Monaco Commission on Plastics and Human Health.Ann Glob Health2022
33429071Resistance to Cyp3a induction by polychlorinated biphenyls, including non-dioxin-like PCB153, in gills of killifish (Fundulus heteroclitus) from New Bedford Harbor.Environ Toxicol Pharmacol2021
34903767Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish.Sci Rep2021
34561524Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish.Commun Biol2021
34006915The chemical defensome of five model teleost fish.Sci Rep2021
33031537Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.Mol Biol Evol2021
33354517Human Health and Ocean Pollution.Ann Glob Health2020
31868891CRISPR-Cas9-Mutated Pregnane X Receptor (pxr) Retains Pregnenolone-induced Expression of cyp3a65 in Zebrafish (Danio rerio) Larvae.Toxicol Sci2020
30371853Sequence Variations in pxr (nr1i2) From Zebrafish (Danio rerio) Strains Affect Nuclear Receptor Function.Toxicol Sci2019
31167942On the occurrence of cytochrome P450 in viruses.Proc Natl Acad Sci U S A2019
28694077Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus.Biochim Biophys Acta Proteins Proteom2018
29991818Independent losses of a xenobiotic receptor across teleost evolution.Sci Rep2018
28062095The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families.Mar Pollut Bull2017
28942070Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison.Aquat Toxicol2017
28582729The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo.Redox Biol2017
27112072Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner.Biochem Pharmacol2016
26432395Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.Mol Phylogenet Evol2016
26620856PCBs: exposures, effects, remediation, and regulation with special emphasis on PCBs in schools.Environ Sci Pollut Res Int2016
27427306Plant lignan secoisolariciresinol suppresses pericardial edema caused by dioxin-like compounds in developing zebrafish: Implications for suppression of morphological abnormalities.Food Chem Toxicol2016
26853319Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.Toxicol Appl Pharmacol2016
25546006Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA.Aquat Toxicol2015
26130508Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio).Free Radic Biol Med2015
26231923Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast.Biochim Biophys Acta2015
25711857Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions.Toxicol Appl Pharmacol2015
25680588Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.Toxicol Appl Pharmacol2015
25424564Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish.Toxicol Sci2015
25553538Regulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor.Aquat Toxicol2015
24361620Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase.Biochim Biophys Acta2014
25402455The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.PLoS One2014
25004462Elimination of nonspecific bands in non-radioactive electrophoretic mobility shift assays using the digoxigenin system.Anal Biochem2014
24858302Involvement of COX2-thromboxane pathway in TCDD-induced precardiac edema in developing zebrafish.Aquat Toxicol2014
23297357The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s.Philos Trans R Soc Lond B Biol Sci2013
24298298Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio.PLoS One2013
24121122Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).Aquat Toxicol2013
23598338The African coelacanth genome provides insights into tetrapod evolution.Nature2013
23770340Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo.Free Radic Biol Med2013
23726801The cytochrome P450 2AA gene cluster in zebrafish (Danio rerio): expression of CYP2AA1 and CYP2AA2 and response to phenobarbital-type inducers.Toxicol Appl Pharmacol2013
23277104Identification and expression of multiple CYP1-like and CYP3-like genes in the bivalve mollusk Mytilus edulis.Aquat Toxicol2013
22356696EZR1: a novel family of highly expressed retroelements induced by TCDD and regulated by a NF-κB-like factor in embryos of zebrafish (Danio rerio).Zebrafish2012
22940225Basal and 3-methylcholanthrene-induced expression of cytochrome P450 1A, 1B and 1C genes in the Brazilian guppy, Poecilia vivipara.Aquat Toxicol2012
23036320Ahr2-dependence of PCB126 effects on the swim bladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish.Toxicol Appl Pharmacol2012
22852852Biomarkers of organic contamination in the South American fish Poecilia vivipara and Jenynsia multidentata.J Toxicol Environ Health A2012
22900608Precision-cut liver slices to investigate responsiveness of deep-sea fish to contaminants at high pressure.Environ Sci Technol2012
22669670Methodological approaches to cytochrome P450 profiling in embryos.Methods Mol Biol2012
20965207New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development.Toxicol Appl Pharmacol2011
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Collaborators

Woods Hole Oceanographic Institution
Co-authored papers 48
Woods Hole Oceanographic Institution
Co-authored papers 42
University of Tennessee Health Science Center
Co-authored papers 6
Cumming School of Medicine, University of Calgary
Co-authored papers 4
Co-authored papers 3
Scripps Institution of Oceanography, university of california san diego
Co-authored papers 3
Co-authored papers 3
Hopkins Marine Station of Stanford University
Co-authored papers 2
The University of North Texas Health Science Center at Fort Worth
Co-authored papers 2
Co-authored papers 2
College of Korean Medicine, Kyung Hee University
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
School of Pharmacy, University of Wisconsin
Co-authored papers 2
University of California Davis
Co-authored papers 2
University of Texas Rio Grande Valley, 1201 West University Drive
Co-authored papers 2
Chulabhorn Research Institute
Co-authored papers 2
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Co-authored papers 1
University of California berkeley
Co-authored papers 1
National Institute of Child Health and Human Development
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
Macquarie University
Co-authored papers 1
Instituto Cajal
Co-authored papers 1
The Affiliated Yantai Yuhuangding Hospital, Qingdao University
Co-authored papers 1
Co-authored papers 1