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Author Details

Karl B Seydel
Kamuzu University of Health Sciences
1990
131
41
PMIDPaper TitleJournal TitlePublished Year
36828342Viral, Bacterial, Metabolic, and Autoimmune Causes of Severe Acute Encephalopathy in Sub-Saharan Africa: A Multicenter Cohort Study.J Pediatr2023
37663790Predicting Acute and Post-Recovery Outcomes in Cerebral Malaria and Other Comas by Optical Coherence Tomography (OCT in CM) - A protocol for an observational cohort study of Malawian children.Wellcome Open Res2023
37520418Differential Effects of Antimalarial Drugs on Parasite Clearance Rates Are Reflected by <i>Plasmodium falciparum</i> Ring Ratio.Open Forum Infect Dis2023
37703350Increased brain microvascular hemoglobin concentrations in children with cerebral malaria.Sci Transl Med2023
37986869Protocol for a Magnetic Resonance Imaging (MRI) Study of Participants in the Fever Randomized Controlled Trial: Does fever control prevent brain injury in malaria?medRxiv2023
37060041The ability of Interleukin-10 to negate haemozoin-related pro-inflammatory effects has the potential to restore impaired macrophage function associated with malaria infection.Malar J2023
37101295Retinal imaging technologies in cerebral malaria: a systematic review.Malar J2023
37474956Correction: The ability of Interleukin-10 to negate haemozoin-related pro-inflammatory effects has the potential to restore impaired macrophage function associated with malaria infection.Malar J2023
37068750Temporal Trends of Blood Glucose in Children with Cerebral Malaria.Am J Trop Med Hyg2023
32845969How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?J Infect Dis2022
35729574Mechanisms of Transcranial Doppler Ultrasound phenotypes in paediatric cerebral malaria remain elusive.Malar J2022
35450856Implementation of a Low-Field Portable MRI Scanner in a Resource-Constrained Environment: Our Experience in Malawi.AJNR Am J Neuroradiol2022
35556124Specific Components Associated With the Endothelial Glycocalyx Are Lost From Brain Capillaries in Cerebral Malaria.J Infect Dis2022
36509055Using Malarial Retinopathy to Improve the Diagnosis of Pediatric Cerebral Malaria.Am J Trop Med Hyg2022
36206262Aggressive antipyretics in central nervous system malaria: Study protocol of a randomized-controlled trial assessing antipyretic efficacy and parasite clearance effects (Malaria FEVER study).PLoS One2022
36067988Multiple Organ Dysfunction Syndrome and Pediatric Logistic Organ Dysfunction-2 Score in Pediatric Cerebral Malaria.Am J Trop Med Hyg2022
36228915Understanding the Intransigence of Malaria in Malawi.Am J Trop Med Hyg2022
36228911Malawi ICEMR Malaria Research: Interactions and Results Influencing Health Policies and Practices.Am J Trop Med Hyg2022
36316704Risk factors for acute kidney injury at presentation among children with CNS malaria: a case control study.Malar J2022
35290461School-Based Malaria Screening and Treatment Reduces Plasmodium falciparum Infection and Anemia Prevalence in Two Transmission Settings in Malawi.J Infect Dis2022
35155278<i>Plasmodium falciparum</i> Parasite Lines Expressing DC8 and Group A PfEMP1 Bind to Brain, Intestinal, and Kidney Endothelial Cells.Front Cell Infect Microbiol2022
34932816Pipecolic Acid, a Putative Mediator of the Encephalopathy of Cerebral Malaria and the Experimental Model of Cerebral Malaria.J Infect Dis2022
34330920Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes.Nat Commun2021
37970136Cerebral Metabolic Crisis in Pediatric Cerebral Malaria.J Pediatr Intensive Care2021
33767384School-based screening and treatment may reduce P. falciparum transmission.Sci Rep2021
33762334Adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria.Sci Adv2021
33901002Post-Malaria Anemia Is Rare in Malawian Children with Cerebral Malaria.Am J Trop Med Hyg2021
34549725Determinants of brain swelling in pediatric and adult cerebral malaria.JCI Insight2021
34663346Plasmodium falciparum clearance time in Malawian children with cerebral malaria: a retrospective cohort study.Malar J2021
34344903Cerebral malaria: insight into pathology from optical coherence tomography.Sci Rep2021
34033654Whole-genome analysis of Malawian Plasmodium falciparum isolates identifies possible targets of allele-specific immunity to clinical malaria.PLoS Genet2021
32168246Amount of Brain Edema Correlates With Neurologic Recovery in Pediatric Cerebral Malaria.Pediatr Infect Dis J2020
31821175CD8+ T cells target cerebrovasculature in children with cerebral malaria.J Clin Invest2020
33087130Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro.Malar J2020
33138796"We can't handle things we don't know about": perceived neurorehabilitation challenges for Malawian paediatric cerebral malaria survivors.BMC Pediatr2020
32579667Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria.Blood Adv2020
32600362Submicroscopic malaria infection is not associated with fever in cross-sectional studies in Malawi.Malar J2020
32554925Plasma cell-free DNA predicts pediatric cerebral malaria severity.JCI Insight2020
32409404Parasite histones mediate blood-brain barrier disruption in cerebral malaria.Clin Med (Lond)2020
29788054Clinical Implications of Asymptomatic Plasmodium falciparum Infections in Malawi.Clin Infect Dis2019
31672143A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria.BMC Pediatr2019
30252032Association Between Age and Plasmodium falciparum Infection Dynamics.Am J Epidemiol2019
31439630Diffusion-Weighted MR Imaging in a Prospective Cohort of Children with Cerebral Malaria Offers Insights into Pathophysiology and Prognosis.AJNR Am J Neuroradiol2019
31600250Malawian children with uncomplicated and cerebral malaria have decreased activated Vγ9Vδ2 γδ T cells which increase in convalescence.PLoS One2019
31396236Comparison of CD8<sup>+</sup> T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria.Front Immunol2019
31219007Impact of Multiplicity of <i>Plasmodium falciparum</i> Infection on Clinical Disease in Malawi.Am J Trop Med Hyg2019
31040236Meta-analysis of Plasmodium falciparum <i>var</i> Signatures Contributing to Severe Malaria in African Children and Indian Adults.mBio2019
30885193Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection.Malar J2019
31138740Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1.mBio2019
30517672Malaria Modeling to Evaluate Treatment for Severe Disease.J Infect Dis2019
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Collaborators

Terrie E Taylor
Kamuzu University of Health Sciences
Co-authored papers 89
Alister G Craig
Malawi-Liverpool-Wellcome Trust Clinical Research Program
Co-authored papers 9
Dyann F Wirth
The Broad Institute
Co-authored papers 5
Dylan S Small
University of Pennsylvania
Co-authored papers 5
Nicole F O'Brien
Nationwide Children's Hospital and The Ohio State University
Co-authored papers 3
Peter W Kaplan
Johns Hopkins Bayview Medical Center
Co-authored papers 3
John D Aitchison
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 3
Curtis Huttenhower
Broad Institute of MIT and Harvard
Co-authored papers 3
David Noah Sather
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 2
Lorenna Vidal
Co-authored papers 2
Vladimir Vigdorovich
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 2
Thurston Herricks
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 2
Jill P Mesirov
University of California San Diego
Co-authored papers 2
Daniel J Park
Broad Institute of MIT and Harvard
Co-authored papers 1
Christina S Kong
Stanford University School of Medicine
Co-authored papers 1
Evangelina Urbina
Hospital de Especialidades Pediatricas, Universidad Nacional Autonoma de Mexico
Co-authored papers 1
Philip Awadalla
Ontario Institute for Cancer Research
Co-authored papers 1
Madiha Raees
The Children's Hospital of Philadelphia
Co-authored papers 1
Hunter Johnson
Nationwide Children's Hospital, The Ohio State University
Co-authored papers 1
Amanda K Lukens
Harvard T.H. Chan School of Public Health
Co-authored papers 1
Dragan Maric
National Institute of Neurological Disorders and Stroke
Co-authored papers 1
Stephen F Schaffner
Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Co-authored papers 1
Nicholas Dambrauskas
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 1
Paul S Frenette
Co-authored papers 1
Philip J Rosenthal
University of California at San Francisco
Co-authored papers 1
Pardis C Sabeti
Harvard University
Co-authored papers 1
Carl J Fichtenbaum
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Nathalie Pochet
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Release 1.2