Skip to Main Content

Author Details

Michael Downey
Ottawa Institute of Systems Biology, University of Ottawa
2005
34
18
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36694267The emerging landscape of eukaryotic polyphosphatases.FEBS Lett2023
37461725Proteomics analysis reveals a role for <i>E. coli</i> polyphosphate kinase in membrane structure and polymyxin resistance during starvation.bioRxiv2023
35133274Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.Elife2022
35421611Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis.Mol Metab2022
35862758Ddp1 Cooperates with Ppx1 to Counter a Stress Response Initiated by Nonvacuolar Polyphosphate.mBio2022
36107838Posttranslational regulation of the GCN5 and PCAF acetyltransferases.PLoS Genet2022
32711095Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases.Biochim Biophys Acta Gene Regul Mech2021
34544285Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding Yeast.mBio2021
34340551Targeting Polyphosphate Kinases in the Fight against Pseudomonas aeruginosa.mBio2021
33998006The promises of lysine polyphosphorylation as a regulatory modification in mammals are tempered by conceptual and technical challenges.Bioessays2021
33420907Model systems for studying polyphosphate biology: a focus on microorganisms.Curr Genet2021
31466120Proteins required for vacuolar function are targets of lysine polyphosphorylation in yeast.FEBS Lett2020
33113373A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells.Cell Rep2020
29671337Nonhistone targets of KAT2A and KAT2B implicated in cancer biology <sup>1</sup>.Biochem Cell Biol2019
29881919From underlying chemistry to therapeutic potential: open questions in the new field of lysine polyphosphorylation.Curr Genet2019
31196146Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.J Exp Clin Cancer Res2019
30804216A synthetic non-histone substrate to study substrate targeting by the Gcn5 HAT and sirtuin HDACs.J Biol Chem2019
31060926SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1.Mol Metab2019
30782636A Stringent Analysis of Polyphosphate Dynamics in <i>Escherichia coli</i>.J Bacteriol2019
29590613A Screen for Candidate Targets of Lysine Polyphosphorylation Uncovers a Conserved Network Implicated in Ribosome Biogenesis.Cell Rep2018
28546450Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling.J Lipid Res2017
27527516Nicotinamide Suppresses the DNA Damage Sensitivity of Saccharomyces cerevisiae Independently of Sirtuin Deacetylases.Genetics2016
26512033Building a KATalogue of acetyllysine targeting and function.Brief Funct Genomics2016
25381059Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1.Mol Cell Proteomics2015
24845677Polymerase stalling during replication, transcription and translation.Curr Biol2014
23973296Gcn5 and sirtuins regulate acetylation of the ribosomal protein transcription factor Ifh1.Curr Biol2013
20670884Repair scaffolding reaches new heights at blocked replication forks.Mol Cell2010
18951093Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.Mol Cell2008
18845848A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae.Genetics2008
16389287Chromatin and DNA repair: the benefits of relaxation.Nat Cell Biol2006
16855385gammaH2AX as a checkpoint maintenance signal.Cell Cycle2006
16564010A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.Cell2006
16299494A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.Nature2006
16159877Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.J Biol Chem2005
  • 1 - 34 of 34

Recommended Authors

Erica A Moehle
Innovative Genomics Institute, University of California berkeley
Career Start Year 2009
Number of shared co-authors 1
Oxana Pogoutse
University of Toronto
Career Start Year 2007
Number of shared co-authors 3
B??rang??re Lombard
Institut Curie, PSL Research University
Career Start Year 2005
Number of shared co-authors 0
Markus Ralser
Charite - Universitatsmedizin Berlin
Career Start Year 2005
Number of shared co-authors 0
Christopher C Ebmeier
University of Colorado
Career Start Year 2004
Number of shared co-authors 0
Chunaram Choudhary
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Career Start Year 2003
Number of shared co-authors 1
Tania Michelle Roberts
ETH Zurich
Career Start Year 2002
Number of shared co-authors 3
Erin M Green
University of Maryland Baltimore County
Career Start Year 2001
Number of shared co-authors 1
Amy Hin Yan Tong
University of Toronto
Career Start Year 1999
Number of shared co-authors 8
Elah Pick
University of Haifa
Career Start Year 1998
Number of shared co-authors 2
Aaron Aslanian
Salk Institute for Biological Studies
Career Start Year 1998
Number of shared co-authors 3
Peter H Thorpe
Queen Mary University
Career Start Year 1997
Number of shared co-authors 1
Seong Hoon Ahn
College of Science and Convergence Technology, Hanyang University
Career Start Year 1997
Number of shared co-authors 5
Ragna Sack
Friedrich Miescher Institute for Biomedical Research
Career Start Year 1997
Number of shared co-authors 0
Patrice Menard
Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Career Start Year 1996
Number of shared co-authors 3
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Career Start Year 1994
Number of shared co-authors 12
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Career Start Year 1994
Number of shared co-authors 5
Scott D Briggs
Purdue University
Career Start Year 1993
Number of shared co-authors 1
Marc R Wilkins
University of New South Wales
Career Start Year 1992
Number of shared co-authors 0
J??rg B??hler
University College London
Career Start Year 1991
Number of shared co-authors 7
Grant W Brown
University of Toronto, 1 King's College Circle
Career Start Year 1991
Number of shared co-authors 10
Erin K O'Shea
Howard Hughes Medical Institute
Career Start Year 1989
Number of shared co-authors 4
John D Aitchison
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Career Start Year 1988
Number of shared co-authors 0
Hiten D Madhani
University of California san francisco
Career Start Year 1986
Number of shared co-authors 1
Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Career Start Year 1986
Number of shared co-authors 4
Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
Career Start Year 1985
Number of shared co-authors 6
Hediye Erdjument-Bromage
Neuroscience Institute, NYU Grossman School of Medicine
Career Start Year 1984
Number of shared co-authors 2
Brenda J Andrews
University of Toronto
Career Start Year 1983
Number of shared co-authors 8
Stephen J Elledge
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Career Start Year 1982
Number of shared co-authors 5
Pamela A Silver
Harvard Medical School
Career Start Year 1979
Number of shared co-authors 3

Collaborators

Daniel Durocher
The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 6
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Emma Bondy-Chorney
University of Ottawa, Canada Ottawa Institute of Systems Biology
Co-authored papers 4
Yuka Sai
Department of Cellular and Molecular Medicine and Ottawa Institute of Systems Biology
Co-authored papers 4
David P Toczyski
University of California San Francisco
Co-authored papers 4
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 3
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 3
Norman E Davey
The Institute of Cancer Research
Co-authored papers 3
Sarah Galicia
Co-authored papers 2
David Lydall
Institute for Cell and Molecular Biosciences, Newcastle University Medical School
Co-authored papers 2
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 2
Charles A Seller
Cell and Developmental Biology Department University of California San Diego
Co-authored papers 2
Mikhajlo K Zubko
Manchester Metropolitan University (MMU)
Co-authored papers 2
Daniel Y L Mao
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Michaela Norgren
University of Ottawa
Co-authored papers 1
Laura Maringele
Newcastle University Biosciences Institute, Newcastle University
Co-authored papers 1
Ema Flores-D??az
Institute of Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 1
Marc Brehme
Delft University of Technology
Co-authored papers 1
Chantal Richer
CHU Sainte-Justine Research Center
Co-authored papers 1
No??l J-M Raynal
Sainte-Justine University Hospital Research Center
Co-authored papers 1
Gabrielle McInnes
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Adrienne Rollie
Children's Hospital Los Angeles
Co-authored papers 1
Daniel Sinnett
Sainte-Justine University Hospital Research Center
Co-authored papers 1
James E Haber
Brandeis University
Co-authored papers 1
Gregory Armaos
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Sandrine Guillard
MedImmune Ltd.
Co-authored papers 1
Dipanjan Chowdhury
Dana-Farber Cancer Institute
Co-authored papers 1
Rajaa Sebaa
Co-authored papers 1
Jacob C Harrison
Duke University Medical Center
Co-authored papers 1
Moutih Rafei
Universite de Montreal
Co-authored papers 1
Release 1.2