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Author Details

David M Langenau
MGH Pathology and Harvard Medical School
1999
93
43
PMIDPaper TitleJournal TitlePublished Year
38058200CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.Haematologica2024
38058200CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.Haematologica2024
37718489Zebrafish as a high throughput model for organ preservation and transplantation research.FASEB J2023
37718489Zebrafish as a high throughput model for organ preservation and transplantation research.FASEB J2023
34965933Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.Cancer Res2022
35581375Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia.Leukemia2022
35982179Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.Nat Cancer2022
35544598Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.Blood2022
35535491Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects.Elife2022
34965933Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.Cancer Res2022
35581375Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia.Leukemia2022
35544598Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.Blood2022
35535491Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects.Elife2022
35982179Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.Nat Cancer2022
32606318PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.Leukemia2021
34117457Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials.Nat Rev Drug Discov2021
33915882Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.J Clin Med2021
32606318PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.Leukemia2021
34415995Single-cell imaging of T cell immunotherapy responses in vivo.J Exp Med2021
33915882Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.J Clin Med2021
34415995Single-cell imaging of T cell immunotherapy responses in vivo.J Exp Med2021
34117457Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials.Nat Rev Drug Discov2021
32251397Zebrafish patient avatars in cancer biology and precision cancer therapy.Nat Rev Cancer2020
31909502The macrophage-expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish.J Leukoc Biol2020
32251397Zebrafish patient avatars in cancer biology and precision cancer therapy.Nat Rev Cancer2020
32826993Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish.Nat Protoc2020
33251223PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.Front Cell Dev Biol2020
32591643A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.Leukemia2020
31909502The macrophage-expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish.J Leukoc Biol2020
33251223PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.Front Cell Dev Biol2020
32826993Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish.Nat Protoc2020
32591643A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.Leukemia2020
30573774Molecularly distinct models of zebrafish Myc-induced B cell leukemia.Leukemia2019
30573774Molecularly distinct models of zebrafish Myc-induced B cell leukemia.Leukemia2019
31031007Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.Cell2019
31222885Insights into pediatric rhabdomyosarcoma research: Challenges and goals.Pediatr Blood Cancer2019
31015418Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.Nat Commun2019
31416720Adult immune compromised zebrafish for xenograft cell transplantation studies.EBioMedicine2019
30952965Longitudinal monitoring of cancer cell subpopulations in monolayers, 3D spheroids, and xenografts using the photoconvertible dye DiR.Sci Rep2019
31416720Adult immune compromised zebrafish for xenograft cell transplantation studies.EBioMedicine2019
31222885Insights into pediatric rhabdomyosarcoma research: Challenges and goals.Pediatr Blood Cancer2019
31015418Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.Nat Commun2019
30952965Longitudinal monitoring of cancer cell subpopulations in monolayers, 3D spheroids, and xenografts using the photoconvertible dye DiR.Sci Rep2019
31031007Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.Cell2019
29749398Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.Leukemia2018
30192230<i>tp53</i> deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.Elife2018
29941549JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.J Exp Med2018
29749398Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.Leukemia2018
29499154Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.Cell Stem Cell2018
30192230<i>tp53</i> deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.Elife2018
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Collaborators

Alex Look
Dana-Farber Cancer Institute
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Sowmya Iyer
Co-authored papers 9
Charles Keller
Children's Cancer Therapy Development Institute
Co-authored papers 9
Sara P Garcia
Co-authored papers 7
Donna Neuberg
Co-authored papers 7
Javed Khan
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Simone Hettmer
University Medical Center Freiburg, University of Freiburg
Co-authored papers 5
Amy J Wagers
Joslin Diabetes Center
Co-authored papers 4
Luca Pinello
Co-authored papers 3
Jack F Shern
Co-authored papers 3
Charles Lee
Co-authored papers 3
Peter J Houghton
The University of Texas Health Science Center at San Antonio
Co-authored papers 2
Elizabeth Stewart
St Jude Children's Research Hospital
Co-authored papers 2
Richard M White
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Nicolae A Iftimia
Massachusetts General Research Institute
Co-authored papers 2
Mario L Suv??
Broad Institute of MIT and Harvard
Co-authored papers 2
Douglas S Hawkins
Co-authored papers 2
Lee J Helman
Osteosarcoma Institute
Co-authored papers 2
David Malkin
Hospital for Sick Children
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J Keith Joung
Massachusetts General Hospital
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Wilhelm Haas
Co-authored papers 2
Atiya Mansoor
Oregon Health & Science University
Co-authored papers 2
Mehmet Toner
Co-authored papers 2
Anthony J Iafrate
Massachusetts General Hospital
Co-authored papers 2
Dennis C Sgroi
Co-authored papers 1
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Christopher R R Bjornson
Stanford University School of Medicine
Co-authored papers 1
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 1
Andrew S Brack
University of California san francisco
Co-authored papers 1
Joel E Michalek
University of Texas Health Science Center
Co-authored papers 1
Release 1.2