Author details

Full Name

Sudha B Biddinger

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37011073	Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms.		2023
35193378	Insulin Prevents Hypercholesterolemia by Suppressing 12Î±-Hydroxylated Bile Acids.	Circulation	2022
35421386	Evaluating human genetic support for hypothesized metabolic disease genes.		2022
35420934	Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.	Science	2022
33468321	Triglycerides in Nonalcoholic Fatty Liver Disease: Guilty Until Proven Innocent.	Trends in Pharmacological Sciences	2021
32738021	Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes.	Pediatr Diabetes	2020
31251698	Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice.	Physiol Genomics	2019
31706902	Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population.	J Clin Lipidol	2019
30633643	microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO.	Physiol Genomics	2019
31543404	Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.		2019
29462566	Nonalcoholic fatty liver disease and gastric bypass surgery regulate serum and hepatic levels of pyruvate kinase isoenzyme M2.	American Journal of Physiology - Endocrinology and Metabolism	2018
29222328	Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways.	J Biol Chem	2018
29300910	FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice.	Endocrinology	2018
29610518	The beta secretase BACE1 regulates the expression of insulin receptor in the liver.	Nature Communications	2018
28093849	Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women.	Pediatr Diabetes	2017
28591582	Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.	Cell Rep	2017
28588146	PCSK9 Is Increased in Youth With Type 1 Diabetes.	Diabetes Care	2017
28714135	YAP suppresses gluconeogenic gene expression through PGC1Î±.	Hepatology	2017
28228332	Calorically restricted diets decrease PCSK9 in overweight adolescents.	Nutr Metab Cardiovasc Dis	2017
26511317	Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation.	Journal of Biological Chemistry	2016
27358438	The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia.	Circulation	2016
26824363	Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients.	Endocrinology	2016
26900642	Effect of Leptin Administration on Circulating Apolipoprotein CIII levels in Patients With Lipodystrophy.	Journal of Clinical Endocrinology and Metabolism	2016
26023080	Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.	Arteriosclerosis, Thrombosis, and Vascular Biology	2015
25849138	Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.	Nat Commun	2015
24516236	Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins.	Journal of Lipid Research	2014
24336217	Diet rapidly and reproducibly alters the human gut microbiome.	Nature	2014
25205222	PKB/Akt phosphorylation of ERRÎ³ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.	Diabetologia	2014
24722248	MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.	Diabetes	2014
23721961	The regulation of ApoB metabolism by insulin.	Trends in Endocrinology and Metabolism	2013
22682225	Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.	Cell Metab	2012
21576825	PKCÎ´ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.	Journal of Clinical Investigation	2011
21183731	Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.	Arteriosclerosis, Thrombosis, and Vascular Biology	2011
21317886	Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction.	Nature Medicine	2011
20203611	SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.	Nature	2010
21109190	Diabetes and insulin in regulation of brain cholesterol metabolism.	Cell Metab	2010
20966023	You deserve what you eat: lessons learned from the study of the melanin-concentrating hormone (MCH)-deficient mice.	Gut	2010
19421055	Dissecting the role of insulin resistance in the metabolic syndrome.	Current Opinion in Lipidology	2009
18587407	Hepatic insulin resistance directly promotes formation of cholesterol gallstones.	Nature Medicine	2008
18249172	Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.	Cell Metab	2008
18347010	Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2.	FASEB Journal	2008
17556363	High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.	Journal of Biological Chemistry	2007
16804073	Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c.	Diabetes	2006
16460269	From mice to men: insights into the insulin resistance syndromes.	Annual Review of Physiology	2006
15855315	Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome.	Diabetes	2005
16087968	The insulin-like growth factor axis: a potential link between glycemic index and cancer.	American Journal of Clinical Nutrition	2005