Skip to Main Content

Author Details

John R Mascola
1991
586
133
PMIDPaper TitleJournal TitlePublished Year
37098956Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.2023
36347257Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.Cell Host Microbe2023
37766115Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes.Vaccines (Basel)2023
37756379A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.Sci Transl Med2023
37738240Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.PLoS Pathog2023
37737588Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.2023
37989731Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.2023
37553406Self-assembling SARS-CoV-2 spike-HBsAg nanoparticles elicit potent and durable neutralizing antibody responses via genetic delivery.NPJ Vaccines2023
37345226Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain.2023
37075126An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans.2023
37196074EV-D68 virus-like particle vaccines elicit cross-clade neutralizing antibodies that inhibit infection and block dissemination.Sci Adv2023
37321165Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.Cell Host Microbe2023
37001964Safety and pharmacokinetics of escalating doses of neutralising monoclonal antibody CAP256V2LS administered with and without VRC07-523LS in HIV-negative women in South Africa (CAPRISA 012B): a phase 1, dose-escalation, randomised controlled trial.2023
37300931Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition.EBioMedicine2023
36729903Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.MAbs2023
36848985Rhesus macaque Bcl-6/Bcl-xL B cell immortalization: Discovery of HIV-1 neutralizing antibodies from lymph node.2023
37544326Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial.Lancet Infect Dis2023
37349337Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.Nat Commun2023
35324257Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.Science2022
36306784Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.Immunity2022
35841885Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.Structure2022
35709309Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.PLoS Pathogens2022
35447072mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron.Cell2022
36356572Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.Immunity2022
36157588Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses.iScience2022
35441178Broadly neutralizing antibodies target the coronavirus fusion peptide.bioRxiv2022
36284200Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life.Scientific Reports2022
35568049Safety and immunogenicity of a trivalent virus-like particle vaccine against western, eastern, and Venezuelan equine encephalitis viruses: a phase 1, open-label, dose-escalation, randomised clinical trial.Lancet Infectious Diseases, The2022
35568025LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.Cell Rep2022
35378757Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.bioRxiv2022
35731888Elicitation of pneumovirus-specific B cell responses by a prefusion-stabilized respiratory syncytial virus F subunit vaccine.Science Translational Medicine2022
35551291Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial.Nature Medicine2022
35609088Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.PLoS ONE2022
35547849Safety and Immunogenicity of a Third Dose of SARS-CoV-2 mRNA Vaccine - An Interim Analysis.2022
35921449Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria.New England Journal of Medicine2022
35783486Safety and immunogenicity of an HIV-1 prefusion-stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label, randomized, dose-escalation, phase 1 clinical trial.eClinicalMedicine2022
36423012Assessment of Crosslinkers between Peptide Antigen and Carrier Protein for Fusion Peptide-Directed Vaccines against HIV-1.Vaccines2022
36517467Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.Nat Commun2022
36582240Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings.Front Immunol2022
34213402Prediction of serum HIV-1 neutralization titers of VRC01 in HIV-uninfected Antibody Mediated Prevention (AMP) trial participants.Hum Vaccin Immunother2022
33972947LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.bioRxiv2022
35319830Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2.Advanced Science2022
34986348Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys.Cell Rep2022
34923559Infusion Reactions After Receiving the Broadly Neutralizing Antibody VRC01 or Placebo to Reduce HIV-1 Acquisition: Results From the Phase 2b Antibody-Mediated Prevention Randomized Trials.J Acquir Immune Defic Syndr2022
34921774Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung.Cell2022
35283191Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2.Journal of Biological Chemistry2022
35264559First-in-human immunoPET imaging of HIV-1 infection using <sup>89</sup>Zr-labeled VRC01 broadly neutralizing antibody.Nat Commun2022
35134995Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention.Journal of Infectious Diseases2022
35115707A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.Nature Medicine2022
35081298SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination.N Engl J Med2022
  • 1 - 50 of 586

Recommended Authors

Collaborators

Co-authored papers 197
Co-authored papers 112
Co-authored papers 102
Co-authored papers 100
Co-authored papers 96
Co-authored papers 88
Co-authored papers 85
Co-authored papers 75
Co-authored papers 72
Co-authored papers 67
Co-authored papers 64
Co-authored papers 61
Co-authored papers 58
National Institute of Allergy and Infectious Disease, National Institute of Health
Co-authored papers 58
Zuckerman Mind Brain Behaviour Institute
Co-authored papers 57
Co-authored papers 54
Co-authored papers 54
Co-authored papers 53
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 42
Co-authored papers 42
Co-authored papers 40
Co-authored papers 40
Co-authored papers 38
Co-authored papers 37
Co-authored papers 28
Co-authored papers 28
Co-authored papers 27
Co-authored papers 26
Co-authored papers 25
Co-authored papers 24