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Author Details
Full Name
Colin R Goding
Affiliation
Ludwig Institute for Cancer Research, University of Oxford
ORCID
Career Start Year
1983
Papers
185
H Index
62
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37972124
Single-cell profiling of MC1R-inhibited melanocytes.
Pigment Cell Melanoma Res
2024
37953065
TFE3 promotes ferroptosis in melanoma.
Pigment Cell Melanoma Res
2024
36701140
AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis.
Cancer Res
2023
37770430
Acetylation reprograms MITF target selectivity and residence time.
Nat Commun
2023
37090624
Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition.
bioRxiv
2023
37410595
The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2.
Cell Rep
2023
37131595
DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.
bioRxiv
2023
36812891
An adverse tumor-protective effect of IDO1 inhibition.
Cell Rep Med
2023
34362555
MC1R Functions, Expression, and Implications for Targeted Therapy.
J Invest Dermatol
2022
35771179
The MITF regulatory network in melanoma.
Pigment Cell Melanoma Res
2022
35912100
Connecting Metabolic Rewiring With Phenotype Switching in Melanoma.
Front Cell Dev Biol
2022
36055199
Sublethal cytochrome c release generates drug-tolerant persister cells.
Cell
2022
34958806
Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion.
J Invest Dermatol
2022
32548785
Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development".
Handb Exp Pharmacol
2021
33744299
TBX3 Promotes Melanoma Migration by Transcriptional Activation of ID1, which Prevents Activation of E-Cadherin by MITF.
J Invest Dermatol
2021
33789714
MITF induces escape from innate immunity in melanoma.
J Exp Clin Cancer Res
2021
34819350
TBX2 controls a proproliferative gene expression program in melanoma.
Genes Dev
2021
34560251
TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors.
Pharmacol Res
2021
34140478
BRN2 is a non-canonical melanoma tumor-suppressor.
Nat Commun
2021
34001865
The protective role of MC1R in chromosome stability and centromeric integrity in melanocytes.
Cell Death Discov
2021
34083536
Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells.
Nat Commun
2021
33262465
Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression.
Oncogene
2021
31595650
ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation.
Pigment Cell Melanoma Res
2020
31733993
Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity.
Mol Cell
2020
33396270
Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-Hypoxic Conditions.
Cancers (Basel)
2020
32603375
Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer.
PLoS Biol
2020
32978520
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression.
Oncogene
2020
32531246
A Reply to ''Evidence that STK19 Is Not an NRAS-Dependent Melanoma Driver".
Cell
2020
32531202
Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.
Mol Cell
2020
30581118
Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming.
Cell Metab
2019
31881017
The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor.
PLoS Genet
2019
31207090
MITF controls the TCA cycle to modulate the melanoma hypoxia response.
Pigment Cell Melanoma Res
2019
31575676
Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities.
Genes Dev
2019
30712867
Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis.
Cell
2019
31123060
MITF-the first 25 years.
Genes Dev
2019
30804224
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
Genes Dev
2019
30787281
Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.
Nat Commun
2019
29235563
Cell and molecular biology: a new section joins the fight against cancer.
Br J Cancer
2018
29992949
A TFEB nuclear export signal integrates amino acid supply and glucose availability.
Nat Commun
2018
30150413
BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.
Proc Natl Acad Sci U S A
2018
29541918
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Acta Neuropathol
2018
29786078
Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy.
Oncogene
2018
29343685
The protective role of DOT1L in UV-induced melanomagenesis.
Nat Commun
2018
27748762
Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.
Oncogene
2017
28096186
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.
Genes Dev
2017
28119061
NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.
EBioMedicine
2017
29207255
Macrophage Cytoplasmic Transfer in Melanoma Invasion.
Dev Cell
2017
29180744
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.
Nat Commun
2017
28584020
KIT<sup>D816V</sup> Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma.
Mol Cancer Res
2017
28869973
Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Nature
2017
1 - 50 of 185
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Aaron G Smith
Dermatology Research Centre, UQ Diamantina Institute, The University of Queensland
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Daniel S Peeper
Netherlands Cancer Institute
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Oscar Krijgsman
The Netherlands Cancer Institute
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Thomas John
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