Author details

Full Name

Jason S McLellan

Affiliation

ORCID

Career Start Year

2002

Papers

176

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37535402	Anamnestic humoral correlates of immunity across SARS-CoV-2 variants of concern.		2023
37756379	A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.	Sci Transl Med	2023
37737588	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.		2023
37794071	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.	Nat Commun	2023
38082099	SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.	Commun Biol	2023
37967532	Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.	Immunity	2023
37865687	Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.		2023
37020354	Progress in vaccine development for infectious diseases-a Keystone Symposia report.	Ann N Y Acad Sci	2023
36951574	Structural Basis for Binding of Neutralizing Antibodies to Binary Toxin.		2023
37390987	A conserved tryptophan in the acylated segment of RTX toxins controls their Î² integrin-independent cell penetration.		2023
36942851	Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses.	Elife	2023
36932063	Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.		2023
35241839	Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking.	Nat Biotechnol	2022
36314826	Long-Lasting Protection Induced by a Polyanhydride Nanovaccine against Respiratory Syncytial Virus in an Outbred Mouse Model.	Journal of Virology	2022
35388686	Analysis of Viral Spike Protein N-Glycosylation Using Ultraviolet Photodissociation Mass Spectrometry.	Analytical Chemistry	2022
35577631	Safety and immunogenicity of an egg-based inactivated Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomized, placebo-controlled, phase 1/2 trial in Vietnam.	Vaccine	2022
35696580	Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus.	Proceedings of the National Academy of Sciences of the United States of America	2022
35944529	Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.	Immunity	2022
36130517	Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.	Cell Rep	2022
35731888	Elicitation of pneumovirus-specific B cell responses by a prefusion-stabilized respiratory syncytial virus F subunit vaccine.	Science Translational Medicine	2022
35731802	Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses.	PLoS Pathogens	2022
35476445	Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.	Sci Adv	2022
35606518	Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice.	NPJ Vaccines	2022
36192374	IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.	Nat Commun	2022
35920558	Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis.	mBio	2022
36380759	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups.	Res Sq	2022
35977491	Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.	Cell Reports	2022
35598506	Principles and practical applications of structure-based vaccine design.		2022
35533563	Protein engineering responses to the COVID-19 pandemic.	Current Opinion in Structural Biology	2022
36683763	A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.	Antib Ther	2022
35275718	Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.	Sci Adv	2022
34793197	Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.	Science	2022
35288548	Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.	Nature Communications	2022
35236990	The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes.	Nature Structural and Molecular Biology	2022
34717971	Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic.	Journal of Molecular Biology	2022
35284808	Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 trial.	EClinicalMedicine	2022
34413500	A glycan gate controls opening of the SARS-CoV-2 spike protein.	Nat Chem	2021
34077751	Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever.	Cell	2021
34013263	Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19.	bioRxiv	2021
33692208	A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.	Journal of Virology	2021
33851158	Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.	bioRxiv	2021
33473140	Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.	Nat Commun	2021
34056628	Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.	Cell Rep Med	2021
33623015	Local computational methods to improve the interpretability and analysis of cryo-EM maps.	Nature Communications	2021
33622975	Prolonged evolution of the human B cell response to SARS-CoV-2 infection.	Science immunology	2021
33947773	Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.	Science	2021
33729773	Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.	Journal of Medicinal Chemistry	2021
33619492	A glycan gate controls opening of the SARS-CoV-2 spike protein.	bioRxiv	2021
34210985	Author Correction: Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.	Nat Commun	2021
34152963	Effects of COVID-19 Vaccination Timing and Risk Prioritization on Mortality Rates, United States.	Emerging Infectious Diseases	2021