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Author Details

Grant R Wilkinson
1 Vanderbilt University Medical Center
1958
233
87
PMIDPaper TitleJournal TitlePublished Year
33585852New up-conversion luminescence in molecular cyano-substituted naphthylsalophen lanthanide(iii) complexes.Chem Commun (Camb)2021
29363356Sedative Plasma Concentrations and Delirium Risk in Critical Illness.Ann Pharmacother2018
19239339Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans.J Infect Dis2009
19034106Tariquidar, a selective P-glycoprotein inhibitor, does not potentiate loperamide's opioid brain effects in humans despite full inhibition of lymphocyte P-glycoprotein.Anesthesiology2008
17996661Clinical sedation scores as indicators of sedative and analgesic drug exposure in intensive care unit patients.Am J Geriatr Pharmacother2007
16537797Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.J Pharmacol Exp Ther2006
17047492Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study.Pharmacogenet Genomics2006
16952489The erythromycin breath test reflects P-glycoprotein function independently of cytochrome P450 3A activity.Clin Pharmacol Ther2006
16912957Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration.Clin Infect Dis2006
16394685Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.Anesthesiology2006
16392089Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study.Clin Infect Dis2006
16424822Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.Pharmacogenet Genomics2006
15917386Drug metabolism and variability among patients in drug response.N Engl J Med2005
16267764Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study.J Infect Dis2005
15102541Genetic variability in CYP3A5 and its possible consequences.Pharmacogenomics2004
15622315Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.AIDS2004
15289786Genetic variability in cytochrome P450 3A5 and in vivo cytochrome P450 3A activity: some answers but still questions.Clin Pharmacol Ther2004
15470333In vivo comparisons of constitutive cytochrome P450 3A activity assessed by alprazolam, triazolam, and midazolam.Clin Pharmacol Ther2004
15116049CYP2C9 and oral anticoagulation therapy with acenocoumarol and warfarin: similarities yet differences.Clin Pharmacol Ther2004
150706845'-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients.Blood2004
12545142Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.Clin Pharmacol Ther2003
14515058Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women.Pharmacogenetics2003
14600574MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.J Acquir Immune Defic Syndr2003
14583845A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128.HIV Clin Trials2003
12621390Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients.Clin Pharmacol Ther2003
12814461Disposition of debrisoquine and nortriptyline in Korean subjects in relation to CYP2D6 genotypes, and comparison with Caucasians.Br J Clin Pharmacol2003
11936561Limited sampling strategy to predict AUC of the CYP3A phenotyping probe midazolam in adults: application to various assay techniques.J Clin Pharmacol2002
12235449Cytochrome P450 2E1 and 3A activities do not differ between Mexicans and European Americans.Clin Pharmacol Ther2002
12362920Single plasma concentrations of 1'-hydroxymidazolam or the ratio of 1'-hydroxymidazolam:midazolam do not predict midazolam clearance in healthy subjects.J Clin Pharmacol2002
11503014Identification of functionally variant MDR1 alleles among European Americans and African Americans.Clin Pharmacol Ther2001
11372001CYP3A activity in European American and Japanese men using midazolam as an in vivo probe.Clin Pharmacol Ther2001
11740342In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration.Pharmacogenetics2001
11459203In vivo inhibition of human CYP1A2 activity by oltipraz.Cancer Chemother Pharmacol2001
11455026Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans.Mol Pharmacol2001
10820137Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes.Drug Metab Dispos2000
10945319CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism.Clin Pharmacol Ther2000
11054262Evidence of a source of HIV type 1 within the central nervous system by ultraintensive sampling of cerebrospinal fluid and plasma.AIDS Res Hum Retroviruses2000
10510153Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent.Br J Clin Pharmacol1999
10463589P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.Cancer Res1999
10411572A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin.J Pharmacol Exp Ther1999
10385138Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone.Cancer Epidemiol Biomarkers Prev1999
10213372Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.Pharm Res1999
10421612OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.Drug Metab Dispos1999
10190659Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio.Br J Clin Pharmacol1999
9889399Human MRP3 transporter: identification of the 5'-flanking region, genomic organization and alternative splice variants.Biochim Biophys Acta1999
9927403Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments].Circulation1999
10591534Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world.Pharmacogenetics1999
10634132Disposition of debrisoquine in Caucasians with different CYP2D6-genotypes including those with multiple genes.Pharmacogenetics1999
10613613Assessment of CYP2D6 and CYP2C19 activity in vivo in humans: a cocktail study with dextromethorphan and chloroguanide alone and in combination.Clin Pharmacol Ther1999
10565843Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.J Pharmacol Exp Ther1999
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Collaborators

Vanderbilt University
Co-authored papers 41
Vanderbilt University Medical Center
Co-authored papers 17
Vanderbilt University Medical Center
Co-authored papers 9
Vanderbilt University School of Medicine
Co-authored papers 8
Washington University School of Medicine
Co-authored papers 4
Osaka City University Graduate School of Medicine
Co-authored papers 4
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 3
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 3
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 3
Northwestern University Feinberg School of Medicine
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Center for Systems Genomics, Pennsylvania State University, University Park
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Clinical Research, University of Pittsburgh
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Harvard School of Public Health
Co-authored papers 2
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 1
New York University
Co-authored papers 1
Co-authored papers 1
Department of Pharmaceutical Services, Vanderbilt University Medical Center
Co-authored papers 1
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 1
Center for AIDS Research, University of California San Diego
Co-authored papers 1
Co-authored papers 1