Author details

Full Name

Subhajyoti De

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37317665	Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer.	Clin Transl Med	2023
37946872	Denoising sparse microbial signals from single-cell sequencing of mammalian host tissues.		2023
35536255	Reconstructing physical cell interaction networks from single-cell data using Neighbor-seq.	Nucleic Acids Research	2022
35584350	Clustered 8-Oxo-Guanine Mutations and Oncogenic Gene Fusions in Microsatellite-Unstable Colorectal Cancer.	JCO Precis Oncol	2022
36035873	Inference on spatial heterogeneity in tumor microenvironment using spatial transcriptomics data.		2022
35898555	KMT2C-deficient tumors have elevated APOBEC mutagenesis and genomic instability in multiple cancers.		2022
36220074	Tumor microbiome links cellular programs and immunity in pancreatic cancer.	Cancer Cell	2022
34721546	Signatures Beyond Oncogenic Mutations in Cell-Free DNA Sequencing for Non-Invasive, Early Detection of Cancer.	Frontiers in Genetics	2021
33574832	Editorial: Genomic Colocalization and Enrichment Analyses.	Front Genet	2021
33718875	Mutational signatures associated with exposure to carcinogenic microplastic compounds bisphenol A and styrene oxide.		2021
33657326	Drivers of dynamic intratumor heterogeneity and phenotypic plasticity.	American Journal of Physiology - Cell Physiology	2021
33039352	Requirement of Bccip for the Regeneration of Intestinal Progenitors.	American Journal of Pathology	2021
33166854	Genomic characterization of malignant pleural mesothelioma and associated clinical outcomes.	Cancer Treat Res Commun	2020
35782971	Loss of the BRCA1-PALB2 interaction accelerates p53-associated tumor development in mice.	Genes Dis	2020
31794893	Loss of Setd4 delays radiation-induced thymic lymphoma in mice.		2020
31953135	Understanding the role of phenotypic switching in cancer drug resistance.	Journal of Theoretical Biology	2020
33257658	Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens.	Nature Communications	2020
32747711	Mutational signature SBS8 predominantly arises due to late replication errors in cancer.	Communications Biology	2020
32746112	Weakly Supervised Deep Nuclei Segmentation Using Partial Points Annotation in Histopathology Images.	IEEE Trans Med Imaging	2020
33015626	Characteristics of mutational signatures of unknown etiology.		2020
31352405	FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue.	G3 (Bethesda)	2019
31747591	Non-Genetic Intra-Tumor Heterogeneity Is a Major Predictor of Phenotypic Heterogeneity and Ongoing Evolutionary Dynamics in Lung Tumors.	Cell Rep	2019
30050055	Activation of S6 signaling is associated with cell survival and multinucleation in hyperplastic skin after epidermal loss of AURORA-A Kinase.	Cell Death and Differentiation	2019
29139326	DNA polymerase Î· mutational signatures are found in a variety of different types of cancer.	Cell Cycle	2018
28498882	Mutational signatures and mutable motifs in cancer genomes.	Brief Bioinform	2018
30108686	Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.	J Extracell Vesicles	2018
30250123	Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data.	Nature Genetics	2018
30292349	Mutation Signatures Depend on Epigenomic Contexts.		2018
30464262	DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.	Nature	2018
29672706	Dissecting the sources of gene expression variation in a pan-cancer analysis identifies novel regulatory mutations.	Nucleic Acids Research	2018
27998972	Looking beyond drivers and passengers in cancer genome sequencing data.	Annals of Oncology	2017
28381541	Personalized Management of Pancreatic Ductal Adenocarcinoma Patients through Computational Modeling.	Cancer Research	2017
28967881	Nuclear topology modulates the mutational landscapes of cancer genomes.	Nature Structural and Molecular Biology	2017
27924834	Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.	Scientific Reports	2016
27026619	IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples.	J Am Med Inform Assoc	2016
26883632	The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection.	Nucleic Acids Res	2016
27146073	HUWE1 interacts with PCNA to alleviate replication stress.	EMBO Reports	2016
26873985	Expression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer.	Journal of Immunology	2016
27272679	Significance of duon mutations in cancer genomes.	Scientific Reports	2016
26589277	SomVarIUS: somatic variant identification from unpaired tissue samples.	Bioinformatics	2016
27573247	Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.	J Biol Chem	2016
27888238	Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.	J Biol Chem	2016
24562872	An assessment of computational methods for estimating purity and clonality using genomic data derived from heterogeneous tumor tissue samples.	Briefings in Bioinformatics	2015
25731168	Polyploidy can drive rapid adaptation in yeast.	Nature	2015
25934800	Signatures of accelerated somatic evolution in gene promoters in multiple cancer types.	Nucleic Acids Res	2015
25240947	Epigenetic diversity in hematopoietic neoplasms.		2014
23956260	The dilemma of choosing the ideal permutation strategy while estimating statistical significance of genome-wide enrichment.	Brief Bioinform	2014
24385541	Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.	Blood	2014
24901363	Histone modifications are associated with transcript isoform diversity in normal and cancer cells.	PLoS Computational Biology	2014
24843000	MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability.	Elife	2014