Author details

Full Name

Heike Biebermann

Affiliation

ORCID

Career Start Year

1996

Papers

146

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34351307	Pharmacotherapy in Childhood Obesity.	Hormone Research in Paediatrics	2022
36362948	Evaluation of Pharmacological Rescue of Melanocortin-4 Receptor Nonsense Mutations by Aminoglycoside.	Life	2022
36009013	A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation.	Biomolecules	2022
35605600	Young Awardees in Endocrinology Presenting Hot Topics.		2022
34352913	Design and Characterization of a Fluorescent Reporter Enabling Live-cell Monitoring of MCT8 Expression.		2022
34561620	Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-Î±-MSH and setmelanotide.	Cell Res	2021
34069457	A New Mechanism in THRA Resistance: The First Disease-Associated Variant Leading to an Increased Inhibitory Function of THRA2.	International Journal of Molecular Sciences	2021
34145382	Correction: Ascorbate-induced oxidative stress mediates TRP channel activation and cytotoxicity in human etoposide-sensitive and -resistant retinoblastoma cells.	Laboratory Investigation	2021
34348096	Melanocortin 4 receptor mutations become common.		2021
32948812	Ascorbate-induced oxidative stress mediates TRP channel activation and cytotoxicity in human etoposide-sensitive and -resistant retinoblastoma cells.	Laboratory Investigation	2021
32619193	Pharmacological treatment strategies for patients with monogenic obesity.	Journal of Pediatric Endocrinology and Metabolism	2020
32143555	Spatiotemporal Changes of Cerebral Monocarboxylate Transporter 8 Expression.	Thyroid	2020
31698479	3-Iodothyronamine Induces Diverse Signaling Effects at Different Aminergic and Non-Aminergic G-Protein Coupled Receptors.		2020
32257954	N- and O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice.	European Thyroid Journal	2020
32242326	Allan-Herndon-Dudley-Syndrome: Considerations about the Brain Phenotype with Implications for Treatment Strategies.		2020
32059383	Differential Signaling Profiles of MC4R Mutations with Three Different Ligands.	International Journal of Molecular Sciences	2020
32544976	Seven Years of Active Thyroid Hormone Research in Germany: Thyroid Hormone Action beyond Classical Concepts.		2020
30784161	Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.	Diabetes Obes Metab	2019
31572197	Non-Functional Trace Amine-Associated Receptor 1 Variants in Patients With Mental Disorders.	Frontiers in Pharmacology	2019
31703413	The Pathogenic TSH Î²-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR.	International Journal of Molecular Sciences	2019
30312418	A New Multisystem Disorder Caused by the GÎ±s Mutation p.F376V.	J Clin Endocrinol Metab	2019
30649231	3-Iodothyronamine-A Thyroid Hormone Metabolite With Distinct Target Profiles and Mode of Action.	Endocrine Reviews	2019
30642682	Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment.	Trends in Molecular Medicine	2019
31417496	Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective.	Frontiers in Endocrinology	2019
29736023	MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.	Nature Medicine	2018
30298050	3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines.	Frontiers in Endocrinology	2018
30055232	An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.	Cellular Signalling	2018
30134862	Relevance of polymorphisms in MC4R and BDNF in short normal stature.	BMC Pediatr	2018
29290039	Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.	Cellular and Molecular Life Sciences	2018
29593543	The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor.	Frontiers in Pharmacology	2018
27788620	3-Iodothyronamine Decreases Expression of Genes Involved in Iodide Metabolism in Mouse Thyroids and Inhibits Iodide Uptake in PCCL3 Thyrocytes.	Thyroid	2017
28861042	3-Iodothyronamine, a Novel Endogenous Modulator of Transient Receptor Potential Melastatin 8?	Frontiers in Endocrinology	2017
28484426	Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work.	Frontiers in Endocrinology	2017
28873389	Treatment of Diabetes and Obesity by Rationally Designed Peptide Agonists Functioning at Multiple Metabolic Receptors.	Endocrine Development	2017
29225575	Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1.	Front Pharmacol	2017
27720451	Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.	Cell	2016
27151573	Oligomerization of GPCRs involved in endocrine regulation.	Journal of Molecular Endocrinology	2016
27387040	Minireview: Insights Into the Structural and Molecular Consequences of the TSH-Î² Mutation C105Vfs114X.	Molecular Endocrinology	2016
27373559	Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort.	Thyroid	2016
27222294	The long N-terminus of the human monocarboxylate transporter 8 is a target of ubiquitin-dependent proteasomal degradation which regulates protein expression and oligomerization capacity.	Molecular and Cellular Endocrinology	2016
27474872	Decreased melanocortin-4 receptor function conferred by an infrequent variant at the human melanocortin receptor accessory protein 2 gene.	Obesity (Silver Spring)	2016
27936173	Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83.	PLoS ONE	2016
27551276	Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.	Frontiers in Endocrinology	2016
25978107	Loss-of-Function Variants in a Hungarian Cohort Reveal Structural Insights on TSH Receptor Maturation and Signaling.	Journal of Clinical Endocrinology and Metabolism	2015
25706283	Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5.	PLoS ONE	2015
25878061	3-iodothyronamine differentially modulates Î±-2A-adrenergic receptor-mediated signaling.	Journal of Molecular Endocrinology	2015
25660412	A novel hemizygous mutation of MAMLD1 in a patient with 46,XY complete gonadal dysgenesis.	Sexual Development	2015
25527620	Modulation of monocarboxylate transporter 8 oligomerization by specific pathogenic mutations.	Journal of Molecular Endocrinology	2015
26051299	Treatment of congenital thyroid dysfunction: Achievements and challenges.		2015
26601081	Two Novel Mutations in the Serpina7 Gene Are Associated with Complete Deficiency of Thyroxine-Binding Globulin.	European Thyroid Journal	2015