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Author Details

JoAnn Trejo
University of California
1990
101
48
PMIDPaper TitleJournal TitlePublished Year
37223976Divergent regulation of α-arrestin ARRDC3 function by ubiquitination.Mol Biol Cell2023
37865315An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses.J Biol Chem2023
37949054Early career Latinas in STEM: Challenges and solutions.Cell2023
37692066Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression.Front Mol Biosci2023
37922871Diversity, Equity and Inclusion in the Laboratory: Strategies to Enhance Inclusive Laboratory Culture.Mol Cell2023
37019623Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration.J Neurosci2023
34465145The α-Arrestin ARRDC3 Is an Emerging Multifunctional Adaptor Protein in Cancer.Antioxid Redox Signal2022
35257745Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells.J Biol Chem2022
35179995COVID-19 threatens faculty diversity: postdoctoral scholars call for action.Mol Biol Cell2022
32838054Subcellular hot spots of GPCR signaling promote vascular inflammation.Curr Opin Endocr Metab Res2021
33722977α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.J Cell Sci2021
35291213A system-wide health sciences faculty mentor training program is associated with improved effective mentoring and institutional climate.J Clin Transl Sci2021
34873055aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.Proc Natl Acad Sci U S A2021
34516752Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption.Sci Signal2021
33268549Post-Translational Modifications of G Protein-Coupled Receptors Control Cellular Signaling Dynamics in Space and Time.Pharmacol Rev2021
32747664GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes.Sci Rep2020
32071217Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function.Proc Natl Acad Sci U S A2020
33257668Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.Nat Commun2020
33253072The burden of service for faculty of color to achieve diversity and inclusion: the minority tax.Mol Biol Cell2020
30353650Endo-lysosomal sorting of G-protein-coupled receptors by ubiquitin: Diverse pathways for G-protein-coupled receptor destruction and beyond.Traffic2019
30129483Faculty Equity, Diversity, Culture and Climate Change in Academic Medicine: A Longitudinal Study.J Natl Med Assoc2019
31194289A modular laboratory course using planarians to study genes involved in tissue regeneration.Biochem Mol Biol Educ2019
30760523G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells.J Biol Chem2019
29348172The α-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling.J Biol Chem2018
30232011A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.Cell Rep2018
29954076GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling.Int J Mol Sci2018
29440509The unfolded protein response regulator ATF6 promotes mesodermal differentiation.Sci Signal2018
27618736Challenges and Opportunities in Protease-Activated Receptor Drug Development.Annu Rev Pharmacol Toxicol2017
29084907A reflection on faculty diversity in the 21st century.Mol Biol Cell2017
28652403Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin.J Biol Chem2017
26845544Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin.Curr Opin Hematol2016
26635365Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.J Biol Chem2016
27301021ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif.PLoS One2016
27402844Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of β-Arrestins.J Biol Chem2016
26030618Group B streptococcal infection and activation of human astrocytes.PLoS One2015
26490116The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein-coupled receptor lysosomal sorting.Mol Biol Cell2015
26360043GPCR sorting at multivesicular endosomes.Methods Cell Biol2015
26391660Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.J Cell Biol2015
26100877N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias.Proc Natl Acad Sci U S A2015
25934730Characterization of thrombin-bound dabigatran effects on protease-activated receptor-1 expression and signaling in vitro.Mol Pharmacol2015
26004360Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development.Dev Biol2015
24489642A general method for site specific fluorescent labeling of recombinant chemokines.PLoS One2014
24680429Atypical regulation of G protein-coupled receptor intracellular trafficking by ubiquitination.Curr Opin Cell Biol2014
24297163Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins.J Biol Chem2014
24377935Endosomal signaling by protease-activated receptors.Methods Enzymol2014
23201781Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling.Cell Signal2013
24064459Cofactoring and dimerization of proteinase-activated receptors.Pharmacol Rev2013
24056371The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization.J Biol Chem2013
23476015Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits β-arrestin-mediated endosomal signaling.J Biol Chem2013
23391721PAR-1 contributes to the innate immune response during viral infection.J Clin Invest2013
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Collaborators

Shaun R Coughlin
Co-authored papers 7
David J Gonzalez
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 5
Joan Heller Brown
Co-authored papers 4
Jacob M Wozniak
The Scripps Research Institute
Co-authored papers 3
Jin Zhang
Co-authored papers 2
Deborah L Wingard
University of California
Co-authored papers 2
Victor Nizet
university of california san diego School of Medicine
Co-authored papers 2
Joseph G Gleeson
University of California
Co-authored papers 1
Neil C Chi
University of California San Diego
Co-authored papers 1
Brenda Andrade
Skaggs School of Pharmacy and Pharmaceutical Sciences
Co-authored papers 1
Hugo C Medina-Munoz
Co-authored papers 1
Richard G S??nchez
University of California
Co-authored papers 1
John Tat
University of California
Co-authored papers 1
Elizabeth T Monta??o
Co-authored papers 1
Peter X Shaw
Shiley Eye Institute, University of California San Diego
Co-authored papers 1
Monica L Gonzalez Ramirez
Co-authored papers 1
Alexandra C Newton
Co-authored papers 1
Morgan E Mouchka
University of California
Co-authored papers 1
John Y-J Shyy
Co-authored papers 1
Bryan L Roth
UNC Chapel Hill School of Medicine
Co-authored papers 1
Jiao Zhang
Co-authored papers 1
Jinae N Roa
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 1
Samantha Hurst
Scripps Research Institute, University of California San Diego, University of Tennessee Knoxville
Co-authored papers 1
Robert J Lefkowitz
Co-authored papers 1
Tzung K Hsiai
University of California Los Angeles
Co-authored papers 1
Gary L Johnson
Co-authored papers 1
Wanda K O'Neal
Co-authored papers 1
Michael Karin
Co-authored papers 1
Ruben Abagyan
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 1
Robert L Wiseman
The Scripps Research Institute
Co-authored papers 1
Release 1.2