Author details

Full Name

Jubao Duan

Affiliation

ORCID

Career Start Year

1995

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36581494	Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.	Biol Psychiatry	2023
37719141	Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.	Cell Genom	2023
38058955	Brain Lipids and Lipid Droplet Dysregulation in Alzheimer's Disease and Neuropsychiatric Disorders.		2023
36504684	Function and development of interneurons involved in brain tissue oxygen regulation.		2022
35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Nature	2022
35526014	BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.	Molecular Neurodegeneration	2022
35459617	Modeling common and rare genetic risk factors of neuropsychiatric disorders in human induced pluripotent stem cells.	Schizophrenia Research	2022
35576194	Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning.	PLoS Comput Biol	2022
35931052	Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.	Am J Hum Genet	2022
36266472	Modeling PTSD neuronal stress responses in a dish.	Nat Neurosci	2022
37724326	Potential diagnostic biomarkers for schizophrenia.	Med Rev (Berl)	2022
34883504	Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia.	Complex Psychiatry	2021
34169279	A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders.	NAR Genom Bioinform	2021
34007041	Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes.	Neuropsychopharmacology	2021
34308291	Cell type-specific and cross-population polygenic risk score analyses of <i>MIR137</i> gene pathway in schizophrenia.	iScience	2021
33647928	CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression.		2021
32732423	Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.	Science	2020
32065989	ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs.	J Neurosci Methods	2020
32399472	The Genetic Relevance of Human Induced Pluripotent Stem Cell-Derived Microglia to Alzheimer's Disease and Major Neuropsychiatric Disorders.	Mol Neuropsychiatry	2020
32984858	Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes.	Patterns (N Y)	2020
31535015	Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia.	Sci Adv	2019
31555746	From Schizophrenia Genetics to Disease Biology: Harnessing New Concepts and Technologies.	J Psychiatr Brain Sci	2019
29631039	Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model.	Stem Cell Res	2018
30115913	Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model.	Transl Psychiatry	2018
29930110	Analysis of shared heritability in common disorders of the brain.	Science	2018
30016992	Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders.	BMC Res Notes	2018
27869829	Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.	Nat Genet	2017
28854564	Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers.	Hum Mol Genet	2017
28418402	Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis.	Transl Psychiatry	2017
28803920	Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.	Cell Stem Cell	2017
29217827	Genome-Wide Association Study of Male Sexual Orientation.	Sci Rep	2017
28036406	Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data.	PLoS Genet	2016
27153221	Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.	PLoS Genet	2016
27402753	Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub.	Proceedings of the National Academy of Sciences of the United States of America	2016
27355579	Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	PLoS Genet	2016
27923066	Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.	PLoS Med	2016
26022996	Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants.	Hum Mol Genet	2015
25575480	Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing.		2015
25399360	Genome-wide scan demonstrates significant linkage for male sexual orientation.	Psychol Med	2015
26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	PLoS Genet	2015
26286434	New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.	Int J Epidemiol	2015
25224588	A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness.	Nat Commun	2014
25434007	A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.	Am J Hum Genet	2014
24217254	Evidence that duplications of 22q11.2 protect against schizophrenia.	Mol Psychiatry	2014
23871472	Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia.	Biol Psychiatry	2014
24675081	MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant.	J Biol Chem	2014
24572595	Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.	Nat Commun	2014
23422947	Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines.	Sci Rep	2013
23904455	Transcriptome study of differential expression in schizophrenia.	Hum Mol Genet	2013
23974872	Genome-wide association analysis identifies 13 new risk loci for schizophrenia.	Nat Genet	2013