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Author Details

Han-Yu Shih
National Eye Institute, National Institutes of Health
2006
42
27
PMIDPaper TitleJournal TitlePublished Year
37090642Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss.bioRxiv2023
34001528Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory.Cold Spring Harb Perspect Biol2022
35034371Stability and change in epigenetic regulation of immune cells.Immunol Rev2022
35303419Mucus sialylation determines intestinal host-commensal homeostasis.Cell2022
34347289Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver.Eur J Immunol2021
33767446Neuronal enhancers are hotspots for DNA single-strand break repair.Nature2021
33841440Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes.Front Immunol2021
33657395MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.Immunity2021
34644563PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8<sup>+</sup> T cells at the expense of central memory.Cell Rep2021
34446580Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring.Science2021
33010223Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells.Immunity2020
31883829Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis.J Autoimmun2020
30650370Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.Immunity2019
31353223Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation.Immunity2019
31209400Single-cell RNA-seq reveals TOX as a key regulator of CD8<sup>+</sup> T cell persistence in chronic infection.Nat Immunol2019
31377117The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1.Mol Cell2019
30712873Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium.Cell2019
30523076Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury.Science2019
29593713Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci.Front Immunol2018
30397350Human retinoic acid-regulated CD161<sup>+</sup> regulatory T cells support wound repair in intestinal mucosa.Nat Immunol2018
29524223NCR<sup>+</sup> ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice.Eur J Immunol2018
29415894Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice.JCI Insight2018
28623086The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells.Immunity2017
29250060Epigenomic Views of Innate Lymphoid Cells.Front Immunol2017
26999798Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.Elife2016
27158840BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.Nat Immunol2016
27156451Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality.Cell2016
26832413The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.Cell Rep2016
25729925IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.Nat Immunol2015
26258942A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires.Nat Immunol2015
25992861Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.Immunity2015
24831346Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.Curr Top Microbiol Immunol2014
25123275Transcriptional and epigenetic networks of helper T and innate lymphoid cells.Immunol Rev2014
23645930Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.J Immunol2013
22418676Light-emitting devices with tunable color from ZnO nanorods grown on InGaN/GaN multiple quantum wells.Opt Express2012
23169622Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.Proc Natl Acad Sci U S A2012
21128009Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization.Immunol Res2011
22079986Regulation of TCRβ allelic exclusion by gene segment proximity and accessibility.J Immunol2011
21924464Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.J Allergy Clin Immunol2011
21643373Ultraviolet electroluminescence from hybrid inorganic/organic ZnO/GaN/poly(3-hexylthiophene) dual heterojunctions.Opt Express2011
20696701Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.J Exp Med2010
16538176Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.Pharmacogenet Genomics2006
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Collaborators

National Institute of Arthritis, National Institutes of Health
Co-authored papers 20
Co-authored papers 14
University of Texas Southwestern Medical Center
Co-authored papers 7
University of Miami Miller School of Medicine
Co-authored papers 6
Howard Hughes Medical Institute
Co-authored papers 6
Co-authored papers 3
National Institute of Allergy and Infectious Diseases
Co-authored papers 3
University Hospital Southampton
Co-authored papers 3
Co-authored papers 3
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 2
Co-authored papers 2
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National Institute of Allergy and Infectious Diseases
Co-authored papers 2
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National Institute of Allergy and Infectious Diseases
Co-authored papers 1
Columbia University
Co-authored papers 1
Stanford University
Co-authored papers 1
Co-authored papers 1
NIH/National Institute of Ageing
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Graduate School of Medicine, Osaka University
Co-authored papers 1
Max Planck Institute for Multidisciplinary Sciences
Co-authored papers 1
Co-authored papers 1
National Institute of Neurological Disorders and Stroke
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
MRC Weatherall Institute of Molecular Medicine, University of Oxford
Co-authored papers 1