Author details

Full Name

Joshua Chiou

Affiliation

ORCID

Career Start Year

2015

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37231096	Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.	Nat Genet	2023
37986756	Genetic discovery and risk prediction for type 1 diabetes in individuals without high-risk HLA-DR3/DR4 haplotypes.		2023
37289818	Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood.	PLoS Genet	2023
36711922	Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.	bioRxiv	2023
37308665	The GPCR-GÎ±<sub>s</sub>-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.	Nat Immunol	2023
36538063	High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease.		2023
36778047	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.	Cell Genom	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
34774128	A single-cell atlas of chromatin accessibility in the human genome.	Cell	2021
34012112	Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.	Nature	2021
33795864	Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.	Nat Genet	2021
33990324	Cardiac cell type-specific gene regulatory programs and disease risk association.	Sci Adv	2021
33983929	Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes.	PLoS Genetics	2021
33505025	Systematic analysis of binding of transcription factors to noncoding variants.	Nature	2021
33654293	Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.	Nat Med	2021
33398137	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2021
34789735	Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.	Nat Commun	2021
34616068	An atlas of gene regulatory elements in adult mouse cerebrum.	Nature	2021
34663987	Mutations and variants of ONECUT1 in diabetes.	Nat Med	2021
33164753	Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes.	Elife	2020
33037424	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2020
31064983	Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.	Nat Commun	2019
31733514	A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells.	iScience	2019
31779666	Common DNA sequence variation influences 3-dimensional conformation of the human genome.	Genome Biol	2019
31171722	Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy.	J Biol Chem	2019
30918008	The long noncoding RNA <i>ROCKI</i> regulates inflammatory gene expression.	EMBO J	2019
30240442	Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.	PLoS Med	2018
30407494	Shared genetic risk contributes to type 1 and type 2 diabetes etiology.	Human Molecular Genetics	2018
29177192	Protein chainmail variants in dsDNA viruses.	AIMS Biophysics	2015