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Author Details

Craig R Malloy
Advanced Imaging Research Center, University of Texas Southwestern Medical Center
1981
283
62
PMIDPaper TitleJournal TitlePublished Year
36285844Oxidation of hyperpolarized [1-[13] C]pyruvate in isolated rat kidneys.NMR Biomed2023
37611583Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples.Cell Metab2023
37392148Isotopomer analyses with the tricarboxylic acid cycle intermediates and exchanging metabolites from the rat kidney.NMR Biomed2023
37224695Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver.Redox Biol2023
36798172Mitochondrial metabolism in primary and metastatic human kidney cancers.bioRxiv2023
36939957<sup>13</sup> C NMR quantification of polyamine syntheses in rat prostate.NMR Biomed2023
36894723Elucidating dynamic anaerobe metabolism with HRMAS [13]C NMR and genome-scale modeling.Nat Chem Biol2023
35997012Recent progress in analysis of intermediary metabolism by ex vivo <sup>13</sup> C NMR.NMR Biomed2023
34687086Dynamic <sup>13</sup> C MR spectroscopy as an alternative to imaging for assessing cerebral metabolism using hyperpolarized pyruvate in humans.Magn Reson Med2022
35658896Detection of increased pyruvate dehydrogenase flux in the human heart during adenosine stress test using hyperpolarized [1-<sup>13</sup>C]pyruvate cardiovascular magnetic resonance imaging.J Cardiovasc Magn Reson2022
35188984Erratum to: Dual-phase imaging of cardiac metabolism using hyperpolarized pyruvate (Magn Reson Med. 2022;87:302-311.).Magn Reson Med2022
34617626Dual-phase imaging of cardiac metabolism using hyperpolarized pyruvate.Magn Reson Med2022
32820540A 32-channel receive array coil for bilateral breast imaging and spectroscopy at 7T.Magn Reson Med2021
35669533<sup>13</sup>C-Labeled Diethyl Ketoglutarate Derivatives as Hyperpolarized Probes of 2-Ketoglutarate Dehydrogenase Activity.Anal Sens2021
33547689Characterization and compensation of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>f</mml:mi><mml:mn>0</mml:mn></mml:msub></mml:math> inhomogeneity artifact in spiral hyperpolarized <sup xmlns:mml="http://www.w3.org/1998/Math/MathML">13</sup> C imaging of the human heart.Magn Reson Med2021
33651680A 16-Channel <sup>13</sup>C Array Coil for Magnetic Resonance Spectroscopy of the Breast at 7T.IEEE Trans Biomed Eng2021
33900680<sup>13</sup> C NMR of glutamate for monitoring the pentose phosphate pathway in myocardium.NMR Biomed2021
33821504Cardiac <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mi>T</mml:mi><mml:mn>2</mml:mn><mml:mo>â¿¿</mml:mo></mml:msubsup></mml:math> measurement of hyperpolarized <sup xmlns:mml="http://www.w3.org/1998/Math/MathML">13</sup> C metabolites using metabolite-selective multi-echo spiral imaging.Magn Reson Med2021
33733082The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA.Metabol Open2021
33772915<sup>31</sup> P-MRS of the healthy human brain at 7 T detects multiple hexose derivatives of uridine diphosphate glucose.NMR Biomed2021
35024596A randomized clinical trial evaluating the effect of empagliflozin on triglycerides in obese adults: Role of visceral fat.Metabol Open2021
34761912Co-Polarized [1-<sup>13</sup>C]Pyruvate and [1,3-<sup>13</sup>C<sub>2</sub>]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment.ACS Sens2021
34102853PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.Circulation2021
34156298Hyperpolarized <sup>13</sup>C MR Spectroscopy Depicts in Vivo Effect of Exercise on Pyruvate Metabolism in Human Skeletal Muscle.Radiology2021
34148138Analysis of steady-state carbon tracer experiments using akaike information criteria.Metabolomics2021
33977579Spectral fitting strategy to overcome the overlap between 2-hydroxyglutarate and lipid resonances at 2.25 ppm.Magn Reson Med2021
34355174Preoperative imaging of glioblastoma patients using hyperpolarized <sup>13</sup>C pyruvate: Potential role in clinical decision making.Neurooncol Adv2021
33179825<sup>15</sup> N-carnitine, a novel endogenous hyperpolarized MRI probe with long signal lifetime.Magn Reson Med2021
32746012A Frequency Translation System for Multi-Channel, Multi-Nuclear MR Spectroscopy.IEEE Trans Biomed Eng2021
32936474Assessment of hepatic pyruvate carboxylase activity using hyperpolarized [1-<sup>13</sup> C]-l-lactate.Magn Reson Med2021
31554675Advances in stable isotope tracer methodology part 1: hepatic metabolism via isotopomer analysis and postprandial lipolysis modeling.J Investig Med2020
31846640Does Tumor FDG-PET Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer?Ann Thorac Surg2020
32055850Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness.Neuro Oncol2020
33344923Imaging Acute Metabolic Changes in Patients with Mild Traumatic Brain Injury Using Hyperpolarized [1-<sup>13</sup>C]Pyruvate.iScience2020
33054563Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.Circ Res2020
32877669Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress.Cell Rep2020
32617517Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.Nat Metab2020
32812387Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver.Physiol Rep2020
32250704Energetic Adaptations and Stress Reserve in the Obese Heart.Circulation2020
32385936Quantitative measurement of redox state in human brain by <sup>31</sup> P MRS at 7T with spectral simplification and inclusion of multiple nucleotide sugar components in data analysis.Magn Reson Med2020
32140658Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic <sup>13</sup>C Magnetic Resonance Spectroscopy.Hepatol Commun2020
32568464Effects of Empagliflozin Treatment on Glycerol-Derived Hepatic Gluconeogenesis in Adults with Obesity: A Randomized Clinical Trial.Obesity (Silver Spring)2020
30472500Hyperpolarized <sup>13</sup>C MRI: Path to Clinical Translation in Oncology.Neoplasia2019
31672442Active pyruvate dehydrogenase and impaired gluconeogenesis in orthotopic hepatomas of rats.Metabolism2019
31712597Real-time hyperpolarized <sup>13</sup>C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4-double knockout mouse livers.Sci Rep2019
31340162Remodeling of substrate consumption in the murine sTAC model of heart failure.J Mol Cell Cardiol2019
30924572Assessing the pentose phosphate pathway using [2, 3-<sup>13</sup> C<sub>2</sub> ]glucose.NMR Biomed2019
31042400A simple method to monitor hepatic gluconeogenesis and triglyceride synthesis following oral sugar tolerance test in obese adolescents.Am J Physiol Regul Integr Comp Physiol2019
30861456Effects of deuteration on transamination and oxidation of hyperpolarized <sup>13</sup>C-Pyruvate in the isolated heart.J Magn Reson2019
30793793Modular <sup>31</sup> P wideband inversion transfer for integrative analysis of adenosine triphosphate metabolism, T<sub>1</sub> relaxation and molecular dynamics in skeletal muscle at 7T.Magn Reson Med2019
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Collaborators

Alexander D Sherry
University of Texas MD Anderson Cancer Center
Co-authored papers 159
Ronald M Peshock
University of Texas Southwestern Medical Center
Co-authored papers 11
Christopher J Madden
University of Texas Southwestern Medical Center
Co-authored papers 6
Michael A Solomon
Clinical Center/Critical Care Medicine Department, National Institutes of Health
Co-authored papers 3
Jamey D Young
Co-authored papers 3
Ronald G Haller
Co-authored papers 3
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 2
Paul M Matthews
UK Dementia Research Institute Centre at Imperial College London
Co-authored papers 2
Elizabeth J Parks
University of Missouri
Co-authored papers 2
Eric N Olson
Co-authored papers 2
Jason W Locasale
Duke University
Co-authored papers 2
Aslan T Turer
University of Texas Southwestern Medical Center Dallas TX USA.
Co-authored papers 2
Dana Mathews
University of Texas Southwestern Medical Center
Co-authored papers 1
Edward D Lewandowski
Co-authored papers 1
Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Markus Ralser
Charite - Universitatsmedizin Berlin
Co-authored papers 1
Julian L Griffin
Cambridge University
Co-authored papers 1
Lynn Bry
Co-authored papers 1
Clary B Clish
Broad Institute of MIT and Harvard
Co-authored papers 1
Jorge R Kizer
Co-authored papers 1
Daniel J Garry
University of Minnesota
Co-authored papers 1
Thomas J Wang
Vanderbilt University
Co-authored papers 1
Mohammed Kanchwala
The University of Texas Southwestern Medical Center
Co-authored papers 1
Gregory Stephanopoulos
Massachusetts Institute of Technology
Co-authored papers 1
Thomas P Mathews
Co-authored papers 1
Victor M Darley-Usmar
University of Alabama at Birmingham
Co-authored papers 1
Yuji Nakada
University of Alabama at Birmingham
Co-authored papers 1
Pierre C Dagher
Co-authored papers 1
Peter C M van Zijl
Johns Hopkins University School of Medicine
Co-authored papers 1
Maciek R Antoniewicz
Massachusetts Institute of Technology
Co-authored papers 1
Release 1.2