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Author Details
Full Name
Tamra E Werbowetski-Ogilvie
Affiliation
University of Manitoba
ORCID
Career Start Year
2001
Papers
33
H Index
19
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37130865
Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma.
Nat Commun
2023
37726268
Cross-species analysis of SHH medulloblastoma models reveals significant inhibitory effects of trametinib on tumor progression.
Cell Death Discov
2023
33714236
From sorting to sequencing in the molecular era: the evolution of the cancer stem cell model in medulloblastoma.
FEBS J
2022
35835937
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.
Commun Biol
2022
36446943
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Nature
2022
36131014
Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Nature
2022
34302487
SNO 2020 diversity survey: defining demographics, racial biases, career success metrics and a path forward for the field of neuro-oncology.
Neuro Oncol
2021
32686664
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.
Nat Commun
2020
30324520
Embryonic Stem Cell Models of Human Brain Tumors.
Methods Mol Biol
2019
29377567
Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma.
Mol Oncol
2018
29930101
CD271<sup>+</sup> Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma.
Cancer Res
2018
28499442
Novel glycolipid agents for killing cisplatin-resistant human epithelial ovarian cancer cells.
J Exp Clin Cancer Res
2017
25227893
Differential cellular responses induced by dorsomorphin and LDN-193189 in chemotherapy-sensitive and chemotherapy-resistant human epithelial ovarian cancer cells.
Int J Cancer
2015
26398939
OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells.
Dis Model Mech
2015
26497209
Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes.
Oncotarget
2015
23555184
Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes.
Neoplasia
2013
23733337
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.
Blood
2013
22213600
In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation.
Stem Cells
2012
21625212
Evidence for the transmission of neoplastic properties from transformed to normal human stem cells.
Oncogene
2011
20605758
Multiparameter comparisons of embryoid body differentiation toward human stem cell applications.
Stem Cell Res
2010
19122652
Characterization of human embryonic stem cells with features of neoplastic progression.
Nat Biotechnol
2009
19956629
Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells.
PLoS One
2009
18226209
Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis.
BMC Cancer
2008
18635398
Pluripotent human stem cell lines: what we can learn about cancer initiation.
Trends Mol Med
2008
17625568
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.
Nature
2007
16636676
Inhibition of medulloblastoma cell invasion by Slit.
Oncogene
2006
17024197
Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells.
Nat Med
2006
16452202
Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha-trypsin inhibitor heavy chain 2.
Cancer Res
2006
15164985
Spheroid preparation from hanging drops: characterization of a model of brain tumor invasion.
J Neurooncol
2004
15561776
SRC regulates actin dynamics and invasion of malignant glial cells in three dimensions.
Mol Cancer Res
2004
15188274
Evidence for a secreted chemorepellent that directs glioma cell invasion.
J Neurobiol
2004
14628206
Soluble factors involved in glioma invasion.
Acta Neurochir (Wien)
2003
11846104
Morphology and migratory behavior of bovine pulmonary artery endothelial cells and C6 astrocytoma cells in a three-dimensional type I collagen matrix.
J Submicrosc Cytol Pathol
2001
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