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Author Details

Tamra E Werbowetski-Ogilvie
University of Manitoba
2001
33
19
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37130865Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma.Nat Commun2023
37726268Cross-species analysis of SHH medulloblastoma models reveals significant inhibitory effects of trametinib on tumor progression.Cell Death Discov2023
33714236From sorting to sequencing in the molecular era: the evolution of the cancer stem cell model in medulloblastoma.FEBS J2022
35835937Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.Commun Biol2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
34302487SNO 2020 diversity survey: defining demographics, racial biases, career success metrics and a path forward for the field of neuro-oncology.Neuro Oncol2021
32686664An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.Nat Commun2020
30324520Embryonic Stem Cell Models of Human Brain Tumors.Methods Mol Biol2019
29377567Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma.Mol Oncol2018
29930101CD271<sup>+</sup> Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma.Cancer Res2018
28499442Novel glycolipid agents for killing cisplatin-resistant human epithelial ovarian cancer cells.J Exp Clin Cancer Res2017
25227893Differential cellular responses induced by dorsomorphin and LDN-193189 in chemotherapy-sensitive and chemotherapy-resistant human epithelial ovarian cancer cells.Int J Cancer2015
26398939OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells.Dis Model Mech2015
26497209Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes.Oncotarget2015
23555184Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes.Neoplasia2013
23733337Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.Blood2013
22213600In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation.Stem Cells2012
21625212Evidence for the transmission of neoplastic properties from transformed to normal human stem cells.Oncogene2011
20605758Multiparameter comparisons of embryoid body differentiation toward human stem cell applications.Stem Cell Res2010
19122652Characterization of human embryonic stem cells with features of neoplastic progression.Nat Biotechnol2009
19956629Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells.PLoS One2009
18226209Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis.BMC Cancer2008
18635398Pluripotent human stem cell lines: what we can learn about cancer initiation.Trends Mol Med2008
17625568IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.Nature2007
16636676Inhibition of medulloblastoma cell invasion by Slit.Oncogene2006
17024197Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells.Nat Med2006
16452202Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha-trypsin inhibitor heavy chain 2.Cancer Res2006
15164985Spheroid preparation from hanging drops: characterization of a model of brain tumor invasion.J Neurooncol2004
15561776SRC regulates actin dynamics and invasion of malignant glial cells in three dimensions.Mol Cancer Res2004
15188274Evidence for a secreted chemorepellent that directs glioma cell invasion.J Neurobiol2004
14628206Soluble factors involved in glioma invasion.Acta Neurochir (Wien)2003
11846104Morphology and migratory behavior of bovine pulmonary artery endothelial cells and C6 astrocytoma cells in a three-dimensional type I collagen matrix.J Submicrosc Cytol Pathol2001
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Collaborators

University of Manitoba
Co-authored papers 15
Hospital for Sick Children
Co-authored papers 8
The Hospital for Sick Children
Co-authored papers 7
Dana-Farber Cancer Institute
Co-authored papers 5
University of Manitoba
Co-authored papers 4
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 4
McMaster University
Co-authored papers 4
The Hospital for Sick Children
Co-authored papers 3
University of Manitoba
Co-authored papers 3
University of Toronto
Co-authored papers 3
University of Manitoba
Co-authored papers 3
Ottawa Hospital Research Institute
Co-authored papers 3
The Hospital for Sick Children
Co-authored papers 3
Institut Curie, PSL Research University, CNRS UMR, INSERM
Co-authored papers 3
Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
The Hospital for Sick Children, University of Toronto
Co-authored papers 2
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 2
Heersink School of Medicine, The University of Alabama at Birmingham
Co-authored papers 2
SIREDO Oncology Center, Institut Curie Hospital, and Universite de Paris
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
Institut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of Manitoba
Co-authored papers 2
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 2
INSERM U8, CNRS UMR5292, Universite de Lyon
Co-authored papers 2
IRCCS San Raffaele Scientific Institute
Co-authored papers 2
University of Toronto
Co-authored papers 2
Groupement Hospitalier EST, Universite de Lyon
Co-authored papers 2
Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)
Co-authored papers 2