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Author Details

Cyrus Khandanpour
University Hospital of Muenster
2008
63
19
PMIDPaper TitleJournal TitlePublished Year
36608320A phase 2 clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma.Blood2023
37760637Daratumumab, Bortezomib, and Dexamethasone for Treatment of Patients with Relapsed or Refractory Multiple Myeloma and Severe Renal Impairment: Results from the Phase 2 GMMG-DANTE Trial.Cancers (Basel)2023
37756525Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.Blood2023
37593101Editorial: New emerging functions of transcription factors and RNA-binding proteins in the development of hematological malignancies.Front Oncol2023
37600821Activity of tafasitamab in combination with rituximab in subtypes of aggressive lymphoma.Front Immunol2023
37190302Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma.Cancers (Basel)2023
37423893Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells.Br J Haematol2023
37035206The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma.Front Oncol2023
37296874Radiotherapy in Combination with Systemic Therapy for Multiple Myeloma-A Critical Toxicity Evaluation in the Modern Treatment Era.Cancers (Basel)2023
37091981Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.Front Cell Dev Biol2023
34792186Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.Br J Haematol2022
35804097GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia.Leukemia2022
35795041Inhibiting PI3K-AKT-mTOR Signaling in Multiple Myeloma-Associated Mesenchymal Stem Cells Impedes the Proliferation of Multiple Myeloma Cells.Front Oncol2022
36428605Efficacy of COVID-19 Booster Vaccines in Patients with Hematologic Malignancies: Experiences in a Real-World Scenario.Cancers (Basel)2022
36457063Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia.J Hematol Oncol2022
35928862The Role of Clonal Evolution on Progression, Blood Parameters, and Response to Therapy in Multiple Myeloma.Front Oncol2022
36328040Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG-HD7): part 1 of an open-label, multicentre, randomised, active-controlled, phase 3 trial.Lancet Haematol2022
35954410Clinical Post-SARS-CoV-2 Infection Scenarios in Vaccinated and Non-Vaccinated Cancer Patients in Three German Cancer Centers: A Retrospective Analysis.Cancers (Basel)2022
36003783Presence of the <i>GFI1-36N</i> single nucleotide polymorphism enhances the response of <i>MLL-AF9</i> leukemic cells to CDK4/6 inhibition.Front Oncol2022
35158832Characteristics and Outcome of Elderly Patients (&gt;55 Years) with Acute Lymphoblastic Leukemia.Cancers (Basel)2022
35158754High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in <i>MLL/AF9</i> Acute Myeloid Leukemia.Cancers (Basel)2022
35251992Efficacy of Daratumumab-Containing Regimens Among Patients With Multiple Myeloma Progressing on Lenalidomide Maintenance: Retrospective Analysis.Front Oncol2022
35077804A synthetic covalent ligand of the C/EBPβ transactivation domain inhibits acute myeloid leukemia cells.Cancer Lett2022
34017122The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape.Nat Immunol2021
33809431Kinetics of Renal Function during Induction in Newly Diagnosed Multiple Myeloma: Results of Two Prospective Studies by the German Myeloma Study Group DSMM.Cancers (Basel)2021
33779471Allogeneic hematopoietic stem cell transplantation for therapy-related myeloid neoplasms following treatment of a lymphoid malignancy.Leuk Lymphoma2021
35008835Curcumin as an Epigenetic Therapeutic Agent in Myelodysplastic Syndromes (MDS).Int J Mol Sci2021
35008207Bcr-TMP, a Novel Nanomolar-Active Compound That Exhibits Both MYB- and Microtubule-Inhibitory Activity.Cancers (Basel)2021
34760702Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis.Front Oncol2021
32444892Long-term survival and polyclonal immunoglobulin reconstitution after allogeneic stem cell transplantation in multiple myeloma.Ann Hematol2020
30679800LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.Leukemia2019
29925903Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice.Leukemia2019
31555592Structural Variants as a Basis for Targeted Therapies in Hematological Malignancies.Front Oncol2019
31508375Role of GFI1 in Epigenetic Regulation of MDS and AML Pathogenesis: Mechanisms and Therapeutic Implications.Front Oncol2019
30837671Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.Leukemia2019
29326122Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome.Haematologica2018
29674496GFI1 is required for <i>RUNX1/ETO</i> positive acute myeloid leukemia.Haematologica2018
29651020GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.Nat Commun2018
28074069Myelodysplastic syndromes and bone loss in mice and men.Leukemia2017
29147018Enforced GFI1 expression impedes human and murine leukemic cell growth.Sci Rep2017
27080012GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome.Exp Hematol2016
26601782Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia.Leukemia2016
27390361Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.Haematologica2016
27467586Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1.PLoS One2016
27216773Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.Exp Hematol2016
26805453Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control.Sci Rep2016
26765577A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A.J Clin Endocrinol Metab2016
27007114High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model.Cell Physiol Biochem2016
26847026GFI1 as a novel prognostic and therapeutic factor for AML/MDS.Leukemia2016
26447191From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation.Blood2015
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Collaborators

Institut de recherches cliniques de Montreal
Co-authored papers 23
University Hospital Essen, University of Duisburg-Essen
Co-authored papers 17
University Hospital Muenster
Co-authored papers 13
University Munster
Co-authored papers 10
University Hospital Essen.
Co-authored papers 10
University Hospital Essen.
Co-authored papers 9
University Hospital Luebeck
Co-authored papers 9
Co-authored papers 6
Co-authored papers 6
University Hospital Munster
Co-authored papers 6
University Hospital Munster
Co-authored papers 5
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 4
University Munster
Co-authored papers 4
Hannover Medical School
Co-authored papers 4
Tokyo Medical and Dental University
Co-authored papers 4
Co-authored papers 3
Institut de recherches cliniques de Montreal
Co-authored papers 3
University Hospital of Schleswig-Holstein
Co-authored papers 3
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 2
Hannover Medical School
Co-authored papers 2
University of Lubeck
Co-authored papers 2
Co-authored papers 2
University of Munster
Co-authored papers 2
Universite de Montreal
Co-authored papers 2
Vanda Pharmaceuticals Inc.
Co-authored papers 2
German Cancer Research Center (DKFZ)
Co-authored papers 2
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
University Hospital of Muenster
Co-authored papers 1
University of Minnesota
Co-authored papers 1
Max-Planck-Institute of Biochemistry Munich
Co-authored papers 1