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Author Details

Florian Fr??hlich
Osnabruck University Department of Biology/Chemistry Bioanalytical Chemistry section
2007
46
22
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36897280Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface.J Cell Biol2023
37794019Structure of the ceramide-bound SPOTS complex.Nat Commun2023
38096056Ferroptosis-protective membrane domains in quiescence.Cell Rep2023
37259913Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole.J Cell Sci2023
36655499The role of lysosomes in lipid homeostasis.Biol Chem2023
35228099Compartmentation and functions of sphingolipids.Curr Opin Cell Biol2022
35404387The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity.J Cell Biol2022
35766971Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis.J Cell Biol2022
35343566The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes.J Cell Sci2022
36098503Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery.Elife2022
35175277A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways.J Cell Biol2022
32515674Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.Autophagy2021
34668759Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole.Mol Biol Cell2021
32499409A trimeric metazoan Rab7 GEF complex is crucial for endocytosis and scavenger function.J Cell Sci2020
33544487The role of very long chain fatty acids in yeast physiology and human diseases.Biol Chem2020
33025734Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex.EMBO Rep2020
32845888Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae.PLoS Genet2020
32840906AP-3 vesicle uncoating occurs after HOPS-dependent vacuole tethering.EMBO J2020
32611771TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast.J Biol Chem2020
30694181A systematic approach to identify recycling endocytic cargo depending on the GARP complex.Elife2019
31216233Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.Mol Biol Cell2019
31368600Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism.EMBO J2019
29870720Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites.Dev Cell2018
30025982Rab GTPase Function in Endosome and Lysosome Biogenesis.Trends Cell Biol2018
27836991Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.J Lipid Res2017
26747648Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis.Biochim Biophys Acta2016
27717283Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion.Proteomics2016
27564575Seipin is required for converting nascent to mature lipid droplets.Elife2016
25519905Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids.J Biol Chem2015
26357016The GARP complex is required for cellular sphingolipid homeostasis.Elife2015
26286023Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.Sci Signal2015
25997101QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.Elife2015
25057013A role for eisosomes in maintenance of plasma membrane phosphoinositide levels.Mol Biol Cell2014
25466257Global proteome turnover analyses of the Yeasts S. cerevisiae and S. pombe.Cell Rep2014
23592334Native SILAC: metabolic labeling of proteins in prototroph microorganisms based on lysine synthesis regulation.Mol Cell Proteomics2013
24165936The transmission of nuclear pore complexes to daughter cells requires a cytoplasmic pool of Nsp1.J Cell Biol2013
23415954Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.Dev Cell2013
22869600Seg1 controls eisosome assembly and shape.J Cell Biol2012
21586754Deep and highly sensitive proteome coverage by LC-MS/MS without prefractionation.Mol Cell Proteomics2011
20526336A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.Nat Struct Mol Biol2010
19564405A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling.J Cell Biol2009
19886975Comparing cellular proteomes by mass spectrometry.Genome Biol2009
19823750Global analysis of the yeast osmotic stress response by quantitative proteomics.Mol Biosyst2009
17962386A peroxisome proliferator-activated receptor gamma-retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription.Mol Pharmacol2008
18820680Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast.Nature2008
18034155Pkh-kinases control eisosome assembly and organization.EMBO J2007
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Collaborators

Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 19
Christer S Ejsing
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 7
Robert V Farese
Harvard T.H. Chan School of Public Health
Co-authored papers 6
Peter Walter
University of California san francisco
Co-authored papers 4
Matthias Mann
Max-Planck Institute of Biochemistry
Co-authored papers 4
Pablo S Aguilar
Instituto de Fisiologia
Co-authored papers 3
Chandramohan Chitraju
Co-authored papers 2
J??rgen Cox
Max-Planck Institute of Biochemistry
Co-authored papers 2
Natalie Krahmer
Co-authored papers 2
Maya Schuldiner
The Weizmann Institute of Science
Co-authored papers 1
Ron Shamir
Tel Aviv University
Co-authored papers 1
Gianni Cesareni
University of Rome 'Tor Vergata'
Co-authored papers 1
J. Wade Harper
Harvard Medical School
Co-authored papers 1
Hannes Braberg
University of California San Francisco
Co-authored papers 1
Michael Rehman
Institute of Biochemistry, Friedrich-Alexander-University of Erlangen-Nurnberg
Co-authored papers 1
Siddhesh S Kamat
Indian Institute of Science Education and Research Pune
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Edward L Huttlin
Harvard Medical School
Co-authored papers 1
Feixia Chu
University of New Hampshire
Co-authored papers 1
Norbert Perrimon
Co-authored papers 1
Steven P Gygi
Harvard Medical School
Co-authored papers 1
Igor Ulitsky
Weizmann Institute of Science
Co-authored papers 1
Nagarjuna Nagaraj
Bruker Daltonics GmbH & Co. KG
Co-authored papers 1
Benjamin F Cravatt
Scripps Research Institute
Co-authored papers 1
Agustina Olivera-Couto
Institut Pasteur de Montevideo
Co-authored papers 1
Matthias Peter
Institute of Biochemistry, ETH Zurich
Co-authored papers 1
Christopher J Stefan
University College London
Co-authored papers 1
Tamar Geiger
Tel Aviv University
Co-authored papers 1
James B Moseley
The Geisel School of Medicine at Dartmouth
Co-authored papers 1
Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Release 1.2