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Author Details

Edith Heard
Institut Curie, PSL Research University, CNRS UMR 5, INSERM U934
1989
186
71
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36727460Species-specific regulation of XIST by the JPX/FTX orthologs.Nucleic Acids Res2023
37708024Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma.Cell Rep2023
37291424RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization.Nat Struct Mol Biol2023
36635505Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages.Nat Cell Biol2023
34312245The Molecular and Nuclear Dynamics of X-Chromosome Inactivation.Cold Spring Harb Perspect Biol2022
35502750Inversion of a topological domain leads to restricted changes in its gene expression and affects interdomain communication.Development2022
35597241XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.Cell2022
36314814Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C.J Vis Exp2022
35013589Gene regulation in time and space during X-chromosome inactivation.Nat Rev Mol Cell Biol2022
34980923Molecular biologists: let's reconnect with nature.Nature2022
32944910Mapping of Chromosome Territories by 3D-Chromosome Painting During Early Mouse Development.Methods Mol Biol2021
33605056H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing.EMBO Rep2021
34890555Xist nucleates local protein gradients to propagate silencing across the X chromosome.Cell2021
34853312SPEN is required for Xist upregulation during initiation of X chromosome inactivation.Nat Commun2021
35088059The X chromosome from telomere to telomere: key achievements and future opportunities.Fac Rev2021
34793229Digging into X chromosome inactivation.Science2021
34791665Noncoding RNAs: biology and applications-a Keystone Symposia report.Ann N Y Acad Sci2021
34504093Locus specific epigenetic modalities of random allelic expression imbalance.Nat Commun2021
32944918Bioinformatic Analysis of Single-Cell Hi-C Data from Early Mouse Embryo.Methods Mol Biol2021
32259458Molecular Mechanisms of Facultative Heterochromatin Formation: An X-Chromosome Perspective.Annu Rev Biochem2020
32025035SPEN integrates transcriptional and epigenetic control of X-inactivation.Nature2020
31759823A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary.Mol Cell2020
32641823Author Correction: In-cell identification and measurement of RNA-protein interactions.Nat Commun2020
32238933Parental-to-embryo switch of chromosome organization in early embryogenesis.Nature2020
30643252Nuclear positioning and pairing of X-chromosome inactivation centers are not primary determinants during initiation of random X-inactivation.Nat Genet2019
31757954In-cell identification and measurement of RNA-protein interactions.Nat Commun2019
31562479Voices in methods development.Nat Methods2019
31175153Kinetics of <i>Xist</i>-induced gene silencing can be predicted from combinations of epigenetic and genomic features.Genome Res2019
31456285The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation.EMBO Rep2019
31341302Advances in epigenetics link genetics to the environment and disease.Nature2019
31537017Xist RNA in action: Past, present, and future.PLoS Genet2019
30962582A symmetric toggle switch explains the onset of random X inactivation in different mammals.Nat Struct Mol Biol2019
31133748The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.Nat Genet2019
30604745The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.Nat Commun2019
30595450The Implication of Early Chromatin Changes in X Chromosome Inactivation.Cell2019
29706539The Ftx Noncoding Locus Controls X Chromosome Inactivation Independently of Its RNA Products.Mol Cell2018
30218360Live Imaging of Xist RNA.Methods Mol Biol2018
30189838Effective normalization for copy number variation in Hi-C data.BMC Bioinformatics2018
29961255Transcriptome Profiling of Single Mouse Oocytes.Methods Mol Biol2018
30230469[France, a refuge for researchers in danger].Med Sci (Paris)2018
30256677X-Chromosome Inactivation: A Crossroads Between Chromosome Architecture and Gene Regulation.Annu Rev Genet2018
30262815Challenges and guidelines toward 4D nucleome data and model standards.Nat Genet2018
27989768XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.Cell Stem Cell2017
28112738Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.Nat Genet2017
28257137Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation.Nat Struct Mol Biol2017
28134930Xist-dependent imprinted X inactivation and the early developmental consequences of its failure.Nat Struct Mol Biol2017
28456962RNA FISH to Study Zygotic Genome Activation in Early Mouse Embryos.Methods Mol Biol2017
28408975X chromosome inactivation: new players in the initiation of gene silencing.F1000Res2017
29686034Topologically Associating Domains in Chromosome Architecture and Gene Regulatory Landscapes during Development, Disease, and Evolution.Cold Spring Harb Symp Quant Biol2017
29101321Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.Nat Commun2017
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Collaborators

Institut Curie, Universite PSL
Co-authored papers 18
University of Massachusetts Chan Medical School
Co-authored papers 11
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 7
The Rockefeller University
Co-authored papers 6
NASA Ames Research Center
Co-authored papers 5
Institut Curie, PSL Research University, CNRS UMR3215, INSERM U934
Co-authored papers 5
HHMI/NYU Langone School of Medicine
Co-authored papers 4
The Gurdon Institute
Co-authored papers 4
Institute of Epigenetics and Stem Cells (IES)
Co-authored papers 3
Berlin Institute of Health (BIH) and Charite
Co-authored papers 3
Institut Curie, PSL Research University
Co-authored papers 3
Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
RIKEN Research Center for Allergy and Immunology
Co-authored papers 2
Stanford University
Co-authored papers 2
Institut Curie, PSL Research University
Co-authored papers 2
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
Co-authored papers 2
Co-authored papers 2
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 2
The Institute of Cancer Research
Co-authored papers 2
Weizmann Institute of Science
Co-authored papers 2
The Babraham Institute
Co-authored papers 2
Co-authored papers 2
Northeastern University
Co-authored papers 2
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
Max Planck Institute of Immunobiology and Epigenetics
Co-authored papers 1
McGovern Institute for Brain Research
Co-authored papers 1
Hainan University
Co-authored papers 1