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Author Details

Benjamin G Barwick
Emory University School of Medicine
2009
55
26
PMIDPaper TitleJournal TitlePublished Year
37767768Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.Blood Cancer Discov2024
37934799ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.Blood Cancer Discov2024
37729611Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency.Blood2024
36580918CD8<sup>+</sup> T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.Immunity2023
38067373Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis.Cancers (Basel)2023
37237081Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.Nat Cancer2023
36256454Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.ACS Nano2022
35511673β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.Haematologica2022
35380688PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.Mol Cancer Res2022
35565356Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients.Cancers (Basel)2022
36170375Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.Sci Adv2022
35927247Venetoclax ex vivo functional profiling predicts improved progression-free survival.Blood Cancer J2022
33248321YAP1 Expression in SCLC Defines a Distinct Subtype With T-cell-Inflamed Phenotype.J Thorac Oncol2021
33738338Oncolytic herpes simplex virus infects myeloma cells <i>in vitro</i> and <i>in vivo</i>.Mol Ther Oncolytics2021
33649772Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.Blood2021
33731701Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.Nat Commun2021
33731366Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma.Clin Cancer Res2021
33926529Ten-eleven translocation protein 1 modulates medulloblastoma progression.Genome Biol2021
33863790The Murine MHC Class II Super Enhancer <i>IA/IE-SE</i> Contains a Functionally Redundant CTCF-Binding Component and a Novel Element Critical for Maximal Expression.J Immunol2021
34778800Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.Blood Cancer Discov2021
34288360Whole-genome analysis of TET dioxygenase function in regulatory T cells.EMBO Rep2021
32144272Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.Nat Commun2020
31811020PD-1 Expression during Acute Infection Is Repressed through an LSD1-Blimp-1 Axis.J Immunol2020
33180919We need CD38 STAT-JAK.Blood2020
32579940CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.Cell Rep2020
32832657Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning.Sci Adv2020
31515279Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes.J Cell Sci2019
31698452Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma.Blood Adv2019
31767829Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.Blood Cancer J2019
31263277Epigenetic programming underpins B cell dysfunction in human SLE.Nat Immunol2019
31231360Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma.Front Immunol2019
2892424014-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.Leukemia2018
30232138The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.J Immunol2018
29765016B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.Nat Commun2018
29712937Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer.Sci Rep2018
29703886Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.Nat Commun2018
29288200EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production.J Immunol2018
27895178Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.J Immunol2017
28993646LSD1 protects against hippocampal and cortical neurodegeneration.Nat Commun2017
29296880CD86 regulates myeloma cell survival.Blood Adv2017
27903915MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.Nucleic Acids Res2017
27082926Factors affecting the persistence of drug-induced reprogramming of the cancer methylome.Epigenetics2016
27500631Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation.Nat Immunol2016
27249108ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells.Sci Rep2016
25753668Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.Nucleic Acids Res2015
25101797Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types.Genes Immun2014
23956425Global DNA methylation remodeling accompanies CD8 T cell effector function.J Immunol2013
24209998Wnt signaling in triple negative breast cancer is associated with metastasis.BMC Cancer2013
24143235Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.PLoS One2013
22300631Age-associated DNA methylation in pediatric populations.Genome Res2012
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Collaborators

Lawrence H Boise
Winship Cancer Institute, Emory University
Co-authored papers 22
Sagar Lonial
Co-authored papers 15
Jeremy M Boss
Emory University School of Medicine
Co-authored papers 14
Craig C Hofmeister
Co-authored papers 6
Jonathan J Keats
Co-authored papers 4
Peter Leif Bergsagel
Co-authored papers 2
Arun P Wiita
University of California San Francisco
Co-authored papers 2
Adeboye O Osunkoya
Emory University School of Medicine
Co-authored papers 2
Eric B Dammer
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 1
Lei Zhu
Emory University School of Medicine
Co-authored papers 1
Donald L Durden
Atrium Health-Levine Cancer Institute
Co-authored papers 1
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
Allan I Levey
Emory University School of Medicine
Co-authored papers 1
Erwin G Van Meir
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 1
Dolores Hambardzumyan
Co-authored papers 1
Makeba Marcoulis
University of California san francisco
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Joan Levy
Co-authored papers 1
Christoph Driessen
Cantonal Hospital St. Gallen
Co-authored papers 1
James E Bradner
Co-authored papers 1
Matthew J Schniederjan
Co-authored papers 1
Daniel J Brat
Co-authored papers 1
Casey S Greene
Co-authored papers 1
Li Chen
Indiana University School of Medicine
Co-authored papers 1
Darell D Bigner
Co-authored papers 1
Yin C Lin
Baylor Institute for Immunology Research
Co-authored papers 1
Casey S Greene
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 1
Aedin C Culhane
Dana-Farber Cancer Institute & Harvard School of Public Health
Co-authored papers 1
Yu-Hsiu Lin
University of California san francisco
Co-authored papers 1
Ian D Ferguson
Yale University School of Medicine
Co-authored papers 1
Amrita Krishnan
Co-authored papers 1
Release 1.2