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Author Details

Solomon Nwaka
Institut fur Biochemie und Molekularbiologie, Universitat Freiburg
1994
41
24
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
31314809Piloting a smartphone-based application for tracking and supply chain management of medicines in Africa.PLoS One2019
28965490Study roadmap for high-throughput development of easy to use and affordable biomarkers as diagnostics for tropical diseases: a focus on malaria and schistosomiasis.Infect Dis Poverty2017
24900603Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties.ACS Med Chem Lett2013
22534528Perspectives: The missing pieces.Nature2012
22838941Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent.BMC Int Health Hum Rights2012
21411020Traditional medicines as a mechanism for driving research innovation in Africa.Malar J2011
22247786Integrated dataset of screening hits against multiple neglected disease pathogens.PLoS Negl Trop Dis2011
21879840Interview with Solomon Nwaka.Future Med Chem2011
21980540Innovative partnerships for drug discovery against neglected diseases.PLoS Negl Trop Dis2011
21896368Drugs and diagnostic innovations to improve global health.Infect Dis Clin North Am2011
20206533Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones.Bioorg Med Chem2010
20808766Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.PLoS Negl Trop Dis2010
20613865Developing ANDI: a novel approach to health product R&D in Africa.PLoS Med2010
20626844CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives.Malar J2010
19410700The African Network for Drugs and Diagnostics Innovation.Lancet2009
19707561Advancing drug innovation for neglected diseases-criteria for lead progression.PLoS Negl Trop Dis2009
18927591Genomic-scale prioritization of drug targets: the TDR Targets database.Nat Rev Drug Discov2008
17851512Mission possible.Nature2007
23489034Challenges in drug discovery for novel antifilarials.Expert Opin Drug Discov2007
23489033Schistosomes: challenges in compound screening.Expert Opin Drug Discov2007
23489030The Concept Paper on the Helminth Drug Initiative. Onchocerciasis/lymphatic filariasis and schistosomiasis: opportunities and challenges for the discovery of new drugs/diagnostics.Expert Opin Drug Discov2007
17080030Innovative lead discovery strategies for tropical diseases.Nat Rev Drug Discov2006
16085175Drug discovery and beyond: the role of public-private partnerships in improving access to new malaria medicines.Trans R Soc Trop Med Hyg2005
15173840Antimalarial drug discovery: efficacy models for compound screening.Nat Rev Drug Discov2004
17291977Medicines for Malaria Venture new developments in antimalarials.Travel Med Infect Dis2004
14668812Virtual drug discovery and development for neglected diseases through public-private partnerships.Nat Rev Drug Discov2003
11734209Activity of human Delta5 and Delta6 desaturases on multiple n-3 and n-6 polyunsaturated fatty acids.FEBS Lett2001
11778843Contribution of Hsc70 to barotolerance in the yeast Saccharomyces cerevisiae.Extremophiles2001
10652100Induction of neutral trehalase Nth1 by heat and osmotic stress is controlled by STRE elements and Msn2/Msn4 transcription factors: variations of PKA effect during stress and growth.Mol Microbiol2000
11097887Evidence for contribution of neutral trehalase in barotolerance of Saccharomyces cerevisiae.Appl Environ Microbiol2000
10527941Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae.Biochem J1999
9738892Stability of neutral trehalase during heat stress in Saccharomyces cerevisiae is dependent on the activity of the catalytic subunits of cAMP-dependent protein kinase, Tpk1 and Tpk2.Eur J Biochem1998
9308367Molecular biology of trehalose and the trehalases in the yeast Saccharomyces cerevisiae.Prog Nucleic Acid Res Mol Biol1998
9797333Evidence for the interplay between trehalose metabolism and Hsp104 in yeast.Appl Environ Microbiol1998
9276477Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein.FEBS Lett1997
8647289Deletion of the ATH1 gene in Saccharomyces cerevisiae prevents growth on trehalose.FEBS Lett1996
8985158The heat shock factor and mitochondrial Hsp70 are necessary for survival of heat shock in Saccharomyces cerevisiae.FEBS Lett1996
7730323Expression and function of the trehalase genes NTH1 and YBR0106 in Saccharomyces cerevisiae.J Biol Chem1995
7883049Phenotypic features of trehalase mutants in Saccharomyces cerevisiae.FEBS Lett1995
7821816Corrected sequence of the yeast neutral trehalase-encoding gene (NTH1): biological implications.Gene1994
8187889Is thermotolerance of yeast dependent on trehalose accumulation?FEBS Lett1994
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Collaborators

Wesley C Van Voorhis
Center for Emerging and Re-emerging Infectious Diseases, University of Washington
Co-authored papers 3
Christiane Hertz-Fowler
Institute of Integrative Biology, University of Liverpool
Co-authored papers 2
Gregory J Crowther
Everett Community College
Co-authored papers 2
Fern??n Ag??ero
Universidad Nacional de San Martin
Co-authored papers 2
David S Roos
University of Pennsylvania
Co-authored papers 2
Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
Co-authored papers 2
Matthew Berriman
Wellcome Sanger Institute
Co-authored papers 2
Fouad Yousif
Ontario Institute for Cancer Research
Co-authored papers 2
Santiago J Carmona
AGORA Cancer Research Center
Co-authored papers 2
Andrew L Hopkins
University of Dundee
Co-authored papers 2
Maria A Doyle
Peter MacCallum Cancer Centre
Co-authored papers 2
Dhanasekaran Shanmugam
CSIR - National Chemical Laboratory
Co-authored papers 2
Christophe L M J Verlinde
University of Washington
Co-authored papers 1
Takashi Suzuki
Co-authored papers 1
James G Beeson
Burnet Institute
Co-authored papers 1
Bissan Al-Lazikani
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Gregg McAllister
Co-authored papers 1
Ian M Carruthers
College of Life Sciences, University of Dundee
Co-authored papers 1
Peter Atadja
Co-authored papers 1
Feng Chen
Bayer Healthcare Pharmaceuticals
Co-authored papers 1
Aaron Riechers
Co-authored papers 1
Robert K Campbell
Serono Research Institute
Co-authored papers 1
Aw Edith Chan
The Walter and Eliza Hall Institute of Medical Research
Co-authored papers 1
Frederick S Buckner
University of Washington
Co-authored papers 1
John P Overington
Institute of Cardiovascular Science, University College London
Co-authored papers 1
Philip J Rosenthal
University of California at San Francisco
Co-authored papers 1
Gaia V Paolini
Pfizer Ltd
Co-authored papers 1
Elizabeth A Winzeler
University of California San Diego
Co-authored papers 1
Martin Aslett
The Wellcome Trust Sanger Institute
Co-authored papers 1
Arnab Pain
King Abdullah University of Science and Technology
Co-authored papers 1
Release 1.2