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Author Details

Karen K Hirschi
University of Virginia School of Medicine
1988
130
49
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37295435MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis.Dev Cell2023
37795485Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans.Front Cardiovasc Med2023
38047075Distinct hypoxia-induced translational profiles of embryonic and adult-derived macrophages.iScience2023
37681311Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction.Circulation2023
37117221Rational engineering of lung alveolar epithelium.NPJ Regen Med2023
37043357Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone.Cell Rep2023
37167971Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice.Cell2023
37197981Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest.Life Sci Alliance2023
37095564Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data.Genome Biol2023
35108221Prdm6 controls heart development by regulating neural crest cell differentiation and migration.JCI Insight2022
35478225A multi-organ chip with matured tissue niches linked by vascular flow.Nat Biomed Eng2022
35857592Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality.Science2022
35695893A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells.J Cell Biol2022
36457147Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics.RNA Biol2022
36202789Endothelial cell cycle state determines propensity for arterial-venous fate.Nat Commun2022
33022674Isolation of Highly Purified and Viable Retinal Endothelial Cells.J Vasc Res2021
33490082Tissue-Resident Macrophage Development and Function.Front Cell Dev Biol2021
33871448Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells.J Vis Exp2021
33844116Vascular endothelial cell specification in health and disease.Angiogenesis2021
34498495Understanding neural stem cell regulation <i>in vivo</i> and applying the insights to cell therapy for strokes.Regen Med2021
34694293Isolation of Murine Retinal Endothelial Cells for Next-Generation Sequencing.J Vis Exp2021
34155901The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.J Am Heart Assoc2021
33035429Regulation of Hemogenic Endothelial Cell Development and Function.Annu Rev Physiol2021
32296715Single Cell Analysis in Vascular Biology.Front Cardiovasc Med2020
31932638Author Correction: Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.Sci Rep2020
33273096The N-glycome regulates the endothelial-to-hematopoietic transition.Science2020
33264627Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification.Cell Rep2020
32154790Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.JCI Insight2020
31448079Molecular regulation of arteriovenous endothelial cell specification.F1000Res2019
31780709Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.Sci Rep2019
31518171Endothelial Cell Development and Its Application to Regenerative Medicine.Circ Res2019
29600160Multifaceted Roles of Connexin 43 in Stem Cell Niches.Curr Stem Cell Rep2018
30075124Resident Endothelial Progenitors Make Themselves at Home.Cell Stem Cell2018
29445140Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Nat Commun2018
27834690Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.Arterioscler Thromb Vasc Biol2017
28104796Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.Science2017
28399402Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow.Dev Cell2017
28181491The molecular basis of endothelial cell plasticity.Nat Commun2017
28467822FGF-dependent metabolic control of vascular development.Nature2017
29247167Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Nat Commun2017
29160307A non-canonical Notch complex regulates adherens junctions and vascular barrier function.Nature2017
28901188Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.Cell Transplant2017
26849156Specification and function of hemogenic endothelium during embryogenesis.Cell Mol Life Sci2016
26497172Bioactive poly(ethylene glycol) hydrogels to recapitulate the HSC niche and facilitate HSC expansion in culture.Biotechnol Bioeng2016
27789626Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.Development2016
27897192PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.Nat Commun2016
27451101Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells.Adv Pharmacol2016
27341393Isolation of Murine Embryonic Hemogenic Endothelial Cells.J Vis Exp2016
26636037Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.Front Oncol2015
26528440Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.Front Oncol2015
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Collaborators

University of Virginia School of Medicine
Co-authored papers 11
Tulane University
Co-authored papers 11
University of Virginia School of Medicine
Co-authored papers 10
Cardiovascular Research Center, Yale University School of Medicine
Co-authored papers 8
University of Virginia School of Medicine
Co-authored papers 7
University of Virginia School of Medicine
Co-authored papers 6
The Hospital for Sick Children
Co-authored papers 5
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 5
University of Illinois
Co-authored papers 4
Cardiovascular Research Center, University of Virginia School of Medicine
Co-authored papers 4
Berne Cardiovascular Research Center, University of Virginia School of Medicine
Co-authored papers 4
University of Virginia
Co-authored papers 4
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 3
Berne Cardiovascular Research Center, University of Virginia School of Medicine
Co-authored papers 2
Co-authored papers 2
The Wellcome Trust Sanger Institute
Co-authored papers 2
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 1
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 1
The Wellcome Trust Sanger Institute
Co-authored papers 1
University of Manchester
Co-authored papers 1
Yale Cardiovascular Research Center Yale University School of Medicine
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University of Oxford
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Boston Children's Hospital
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Columbia University
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