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Author Details
Full Name
Karen K Hirschi
Affiliation
University of Virginia School of Medicine
ORCID
Career Start Year
1988
Papers
130
H Index
49
Expertise
CM4AI Collaborator
Gloria M Sheynkman (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37295435
MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis.
Dev Cell
2023
37795485
Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans.
Front Cardiovasc Med
2023
38047075
Distinct hypoxia-induced translational profiles of embryonic and adult-derived macrophages.
iScience
2023
37681311
Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction.
Circulation
2023
37117221
Rational engineering of lung alveolar epithelium.
NPJ Regen Med
2023
37043357
Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone.
Cell Rep
2023
37167971
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice.
Cell
2023
37197981
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest.
Life Sci Alliance
2023
37095564
Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data.
Genome Biol
2023
35108221
Prdm6 controls heart development by regulating neural crest cell differentiation and migration.
JCI Insight
2022
35478225
A multi-organ chip with matured tissue niches linked by vascular flow.
Nat Biomed Eng
2022
35857592
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality.
Science
2022
35695893
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells.
J Cell Biol
2022
36457147
Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics.
RNA Biol
2022
36202789
Endothelial cell cycle state determines propensity for arterial-venous fate.
Nat Commun
2022
33022674
Isolation of Highly Purified and Viable Retinal Endothelial Cells.
J Vasc Res
2021
33490082
Tissue-Resident Macrophage Development and Function.
Front Cell Dev Biol
2021
33871448
Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells.
J Vis Exp
2021
33844116
Vascular endothelial cell specification in health and disease.
Angiogenesis
2021
34498495
Understanding neural stem cell regulation <i>in vivo</i> and applying the insights to cell therapy for strokes.
Regen Med
2021
34694293
Isolation of Murine Retinal Endothelial Cells for Next-Generation Sequencing.
J Vis Exp
2021
34155901
The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.
J Am Heart Assoc
2021
33035429
Regulation of Hemogenic Endothelial Cell Development and Function.
Annu Rev Physiol
2021
32296715
Single Cell Analysis in Vascular Biology.
Front Cardiovasc Med
2020
31932638
Author Correction: Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.
Sci Rep
2020
33273096
The N-glycome regulates the endothelial-to-hematopoietic transition.
Science
2020
33264627
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification.
Cell Rep
2020
32154790
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.
JCI Insight
2020
31448079
Molecular regulation of arteriovenous endothelial cell specification.
F1000Res
2019
31780709
Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.
Sci Rep
2019
31518171
Endothelial Cell Development and Its Application to Regenerative Medicine.
Circ Res
2019
29600160
Multifaceted Roles of Connexin 43 in Stem Cell Niches.
Curr Stem Cell Rep
2018
30075124
Resident Endothelial Progenitors Make Themselves at Home.
Cell Stem Cell
2018
29445140
Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.
Nat Commun
2018
27834690
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.
Arterioscler Thromb Vasc Biol
2017
28104796
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.
Science
2017
28399402
Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow.
Dev Cell
2017
28181491
The molecular basis of endothelial cell plasticity.
Nat Commun
2017
28467822
FGF-dependent metabolic control of vascular development.
Nature
2017
29247167
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.
Nat Commun
2017
29160307
A non-canonical Notch complex regulates adherens junctions and vascular barrier function.
Nature
2017
28901188
Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.
Cell Transplant
2017
26849156
Specification and function of hemogenic endothelium during embryogenesis.
Cell Mol Life Sci
2016
26497172
Bioactive poly(ethylene glycol) hydrogels to recapitulate the HSC niche and facilitate HSC expansion in culture.
Biotechnol Bioeng
2016
27789626
Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.
Development
2016
27897192
PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.
Nat Commun
2016
27451101
Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells.
Adv Pharmacol
2016
27341393
Isolation of Murine Embryonic Hemogenic Endothelial Cells.
J Vis Exp
2016
26636037
Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.
Front Oncol
2015
26528440
Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.
Front Oncol
2015
1 - 50 of 130
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Tulane University
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5
Anne M Dickinson
Translational and Clinical Research Institute, Newcastle University
Co-authored papers
5
Anupreet Kour
University of Illinois
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Elizabeth A Nelson
Cardiovascular Research Center, University of Virginia School of Medicine
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4
Bipul R Acharya
Berne Cardiovascular Research Center, University of Virginia School of Medicine
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4
Gloria M Sheynkman (CM4AI)
University of Virginia
Co-authored papers
4
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
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3
Stephanie P McDonnell
Berne Cardiovascular Research Center, University of Virginia School of Medicine
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2
Robert Langer
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Allan Bradley
The Wellcome Trust Sanger Institute
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Gordana Vunjak-Novakovic
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