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Author Details

Thomas W Blackwell
1999
50
21
PMIDPaper TitleJournal TitlePublished Year
37425716Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.bioRxiv2023
37848499Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA.2023
37601969Multiset correlation and factor analysis enables exploration of multi-omics data.Cell Genom2023
37662416Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies.bioRxiv2023
37804200Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.J Am Heart Assoc2023
37868038The functional impact of rare variation across the regulatory cascade.Cell Genom2023
36778386Structural variation across 138,134 samples in the TOPMed consortium.Res Sq2023
37126548The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.Sci Adv2023
36747810Structural variation across 138,134 samples in the TOPMed consortium.bioRxiv2023
37046083Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.Nature2023
36463326Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis.Int J Obes (Lond)2023
35087136Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.Sci Rep2022
35389749Monogenic and Polygenic Contributions to QTc Prolongation in the Population.Circulation2022
35385311Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.Sci Adv2022
35504290TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data.Am J Hum Genet2022
35501457Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program.Commun Biol2022
36481753Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program.Nat Commun2022
34553764Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative.Hum Mol Genet2022
34582791Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.Am J Hum Genet2021
34050697Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.Aging Cell2021
33887194Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.Am J Hum Genet2021
33720349Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries.Genetics2021
34087167Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.Am J Hum Genet2021
34319147Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis.Circ Genom Precis Med2021
32966749Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans.Am J Respir Crit Care Med2021
34914532Pangenomics enables genotyping of known structural variants in 5202 diverse genomes.Science2021
35036986Association of mitochondrial DNA copy number with cardiometabolic diseases.Cell Genom2021
33339817Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.Nat Commun2020
31665830Identification of CFTR variants in Latino patients with cystic fibrosis from the Dominican Republic and Puerto Rico.Pediatr Pulmonol2020
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
30535219Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.JAMA2018
29279374Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.Proc Natl Acad Sci U S A2018
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
27980614Omics-squared: human genomic, transcriptomic and phenotypic data for genetic analysis workshop 19.BMC Proc2016
27398621The genetic architecture of type 2 diabetes.Nature2016
25519314Data for Genetic Analysis Workshop 18: human whole genome sequence, blood pressure, and simulated phenotypes in extended pedigrees.BMC Proc2014
23788246Recommended joint and meta-analysis strategies for case-control association testing of single low-count variants.Genetic Epidemiology2013
21917140The functional spectrum of low-frequency coding variation.Genome Biol2011
18287020Quantifying changes in the thiol redox proteome upon oxidative stress in vivo.Proc Natl Acad Sci U S A2008
17411336Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function.PLoS Comput Biol2007
17411398Evolutionary-conserved gene expression response profiles across mammalian tissues.OMICS2007
16525410Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study.Nat Biotechnol2006
16646984Novel gene and gene model detection using a whole genome open reading frame analysis in proteomics.Genome Biol2006
16104056Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.Proteomics2005
16104057Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project.Proteomics2005
11448880Conformational model for binding site recognition by the E.coli MetJ transcription factor.Bioinformatics2001
11473017Probabilistic approaches to the use of higher order clone relationships in physical map assembly.Bioinformatics2001
10786286Identity by descent genome segmentation based on single nucleotide polymorphism distributions.Proc Int Conf Intell Syst Mol Biol1999
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