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Author Details

Ruud H Brakenhoff
Vrije Universiteit Amsterdam
1986
235
58
PMIDPaper TitleJournal TitlePublished Year
37828725An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy.Mol Cancer Ther2024
34601770Associations between clinical and histopathological characteristics in oral leukoplakia.Oral Dis2023
37749621The role of differentiated dysplasia in the prediction of malignant transformation of oral leukoplakia.J Oral Pathol Med2023
37745365A clinicogenomic model including GARD predicts outcome for radiation treated patients with HPV+ oropharyngeal squamous cell carcinoma.medRxiv2023
37936517The value of regular follow-up of oral leukoplakia for early detection of malignant transformation.Oral Dis2023
35765231Oral leukoplakia classification and staging system with incorporation of differentiated dysplasia.Oral Dis2023
37455307MRI-based radiomic prognostic signature for locally advanced oral cavity squamous cell carcinoma: development, testing and comparison with genomic prognostic signatures.Biomark Res2023
37432446The course of health-related quality of life in the first 2 years after a diagnosis of head and neck cancer: the role of personal, clinical, psychological, physical, social, lifestyle, disease-related, and biological factors.Support Care Cancer2023
36912284Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource.Int J Cancer2023
36639418Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.Commun Biol2023
36637878<i>In Vitro</i> CRISPR-Cas12a-Based Detection of Cancer-Associated <i>TP53</i> Hotspot Mutations Beyond the crRNA Seed Region.CRISPR J2023
36796393Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis.Lancet Oncol2023
36449687Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation.Clin Cancer Res2023
36069231Oral cancer prediction by noninvasive genetic screening.Int J Cancer2023
36053327Radiation modulates expression and related activities of c-Met protein in oral tongue squamous cell carcinoma cell lines.J Cancer Res Clin Oncol2023
34267108Age-group-specific trend analyses of oropharyngeal squamous cell carcinoma incidence from 1989 to 2018 and risk factors profile by age-group in 2015-2018: a population-based study in The Netherlands.Eur J Cancer Prev2022
35406587Unmet Needs and Perspectives in Oral Cancer Prevention.Cancers (Basel)2022
35451620Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis.Virchows Arch2022
36442320Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification.EBioMedicine2022
35973619Disease outcome and associated factors after definitive platinum based chemoradiotherapy for advanced stage HPV-negative head and neck cancer.Radiother Oncol2022
36055228Detection and localization of early- and late-stage cancers using platelet RNA.Cancer Cell2022
36290836Psychoneurological Symptoms and Biomarkers of Stress and Inflammation in Newly Diagnosed Head and Neck Cancer Patients: A Network Analysis.Curr Oncol2022
35130834Secreted protein markers in oral squamous cell carcinoma (OSCC).Clin Proteomics2022
35065597Study retention and attrition in a longitudinal cohort study including patient-reported outcomes, fieldwork and biobank samples: results of the Netherlands quality of life and Biomedical cohort study (NET-QUBIC) among 739 head and neck cancer patients and 262 informal caregivers.BMC Med Res Methodol2022
33107152Development of a multiomics database for personalized prognostic forecasting in head and neck cancer: The Big Data to Decide EU Project.Head Neck2021
33634865The unveiled reality of human papillomavirus as risk factor for oral cavity squamous cell carcinoma.Int J Cancer2021
33605260[Identification of differentiated dysplasia improves prediction of oral leukoplakia at increased risk of malignant progression].Ned Tijdschr Tandheelkd2021
35047999At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma.Front Oral Health2021
34738049Clinical Validity of a Prognostic Gene Expression Cluster-Based Model in Human Papillomavirus-Positive Oropharyngeal Carcinoma.JCO Precis Oncol2021
34681717NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models.Int J Mol Sci2021
34071997Resection Margins in Head and Neck Cancer Surgery: An Update of Residual Disease and Field Cancerization.Cancers (Basel)2021
34210048A Prospectively Validated Prognostic Model for Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Based on Radiomics of Computed Tomography Images.Cancers (Basel)2021
34204886Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications.Cancers (Basel)2021
34311328The important role of cisplatin in the treatment of HPV-positive oropharyngeal cancer assessed by real-world data analysis.Oral Oncol2021
33454834The course of health-related quality of life from diagnosis to two years follow-up in patients with oropharyngeal cancer: does HPV status matter?Support Care Cancer2021
32161279Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer.Sci Rep2020
31837430Development and Validation of a Novel and Rapid Molecular Detection Method for High-Risk Human Papillomavirus in Formalin-Fixed, Paraffin-Embedded Tumor Tissue.J Mol Diagn2020
31896811Incorporation of differentiated dysplasia improves prediction of oral leukoplakia at increased risk of malignant progression.Mod Pathol2020
32047167Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition.Sci Rep2020
31980916Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors.Cancer Immunol Immunother2020
33038723Annual malignant transformation rate of oral leukoplakia remains consistent: A long-term follow-up study.Oral Oncol2020
32795611DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery.Genomics Proteomics Bioinformatics2020
32590298Comprehensive multiparameter genetic analysis improves circulating tumor DNA detection in head and neck cancer patients.Oral Oncol2020
32585557Expression of let-7i and miR-192 is associated with resistance to cisplatin-based chemoradiotherapy in patients with larynx and hypopharynx cancer.Oral Oncol2020
32722718Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy.PLoS One2020
32442178Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy.PLoS One2020
32500196Outcome prediction of head and neck squamous cell carcinoma by MRI radiomic signatures.Eur Radiol2020
32413532Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy.Radiother Oncol2020
32167160Ovarian cancer-derived copy number alterations signatures are prognostic in chemoradiotherapy-treated head and neck squamous cell carcinoma.Int J Cancer2020
30596895ACE: absolute copy number estimation from low-coverage whole-genome sequencing data.Bioinformatics2019
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Collaborators

Location Vrije Universiteit Amsterdam
Co-authored papers 113
Cancer Center Amsterdam, Vrije Universiteit Amsterdam
Co-authored papers 21
Maastricht University Medical Centre
Co-authored papers 15
University Hospital of Parma
Co-authored papers 10
Heinrich-Heine University
Co-authored papers 9
Amsterdam University Medical Centers (Amsterdam UMC)
Co-authored papers 9
Fondazione IRCCS Istituto Nazionale dei Tumori and University of Milan
Co-authored papers 9
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, University of Milan
Co-authored papers 8
University Medical Center Utrecht
Co-authored papers 7
Maastricht University
Co-authored papers 7
The Netherlands Cancer Institute
Co-authored papers 7
Utrecht University
Co-authored papers 6
Co-authored papers 5
Maastricht University Medical Center (MUMC+)
Co-authored papers 5
Fondazione IRCCS Istituto Nazionale dei Tumori
Co-authored papers 5
Cancer Center Amsterdam
Co-authored papers 3
University of Paris
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 3
Research Institute GROW, Maastricht University
Co-authored papers 3
Jewish General Hospital, McGill University
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
University of Toronto, Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
Jewish General Hospital
Co-authored papers 2
Cancer Center Amsterdam, Vrije Universiteit Amsterdam
Co-authored papers 2
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 2
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
University of Dundee
Co-authored papers 1
New York Presbyterian Hospital
Co-authored papers 1