Author details

Full Name

Claudia Lukas

Affiliation

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

Emma Lundberg (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35590073	Deep Visual Proteomics defines single-cell identity and heterogeneity.	Nat Biotechnol	2022
35484586	Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.	Genome Biol	2022
34625544	The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome.	Nat Commun	2021
30804506	53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage.	Nat Cell Biol	2019
31645724	Stabilization of chromatin topology safeguards genome integrity.	Nature	2019
29548335	Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.	Genome Biol	2018
27348077	53BP1 fosters fidelity of homology-directed DNA repair.	Nat Struct Mol Biol	2016
27984746	Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.	Mol Cell	2016
27976684	Profiling DNA damage response following mitotic perturbations.	Nat Commun	2016
25916843	Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.	Nucleic Acids Res	2015
25064736	The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.	Nat Cell Biol	2014
23393250	Molecular biology. Shielding broken DNA for a quick fix.	Science	2013
24055346	The chromatin scaffold protein SAFB1 renders chromatin permissive for DNA damage signaling.	Mol Cell	2013
24267891	ATR prohibits replication catastrophe by preventing global exhaustion of RPA.	Cell	2013
23615962	The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.	J Biol Chem	2013
22075984	Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.	Cell Death Differ	2012
23042605	DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks.	Nat Struct Mol Biol	2012
22773103	LEDGF (p75) promotes DNA-end resection and homologous recombination.	Nat Struct Mol Biol	2012
22884692	TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.	Cell	2012
22492721	Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.	J Cell Biol	2012
22456334	Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage.	Cell Cycle	2012
22234878	The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.	Nucleic Acids Res	2012
21394101	Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia.	Cell Death Differ	2011
21968989	More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance.	Nat Cell Biol	2011
21317883	53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.	Nat Cell Biol	2011
20023648	HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.	Nat Cell Biol	2010
20805324	The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.	J Cell Biol	2010
19203579	RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.	Cell	2009
18001824	RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.	Cell	2007
17965729	Human CtIP promotes DNA end resection.	Nature	2007
16327781	ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.	Nat Cell Biol	2006
16862143	Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.	Nat Cell Biol	2006
16880517	Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.	Mol Cell Biol	2006
16618811	Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.	J Cell Biol	2006
15988581	Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges.	Chromosoma	2005
15829956	DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.	Nature	2005
16009723	Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.	J Cell Biol	2005
15459660	Checking on DNA damage in S phase.	Nat Rev Mol Cell Biol	2004
15604269	Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.	Cancer Res	2004
15279786	Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time.	DNA Repair (Amst)	2004
15201865	Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.	EMBO J	2004
15311285	Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase.	Nat Cell Biol	2004
12754735	Deregulation of the RB pathway in human testicular germ cell tumours.	J Pathol	2003
12598907	Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage.	Nat Cell Biol	2003
12832461	Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research.	Mol Cell Proteomics	2003
11901424	Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation.	Nat Cell Biol	2002
11431331	DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology.	Cancer Res	2001
11340163	A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.	Mol Cell Biol	2001
11571648	Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.	Oncogene	2001
10827953	Rapid destruction of human Cdc25A in response to DNA damage.	Science	2000

1 - 50 of 54

Marc Wiedner

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

Career Start Year 2013

Number of shared co-authors 1

Nicole Hustedt

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital

Career Start Year 2012

Number of shared co-authors 1

Sichun Lin

Department of Pharmaceutical Sciences, University of Toronto

Career Start Year 2012

Number of shared co-authors 0

Andrew Seeber

Center for Advanced Imaging, Harvard University

Career Start Year 2012

Number of shared co-authors 0

David Gallo

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital

Career Start Year 2010

Number of shared co-authors 1

Aude Gu??nol??

CNRS, Universite de Toulouse

Career Start Year 2009

Number of shared co-authors 0

Georgia Velimezi

University of Patras

Career Start Year 2008

Number of shared co-authors 1

Laura Pontano Vaites

Harvard Medical School

Career Start Year 2007

Number of shared co-authors 1

Joanna I Loizou

Center for Cancer Research, Comprehensive Cancer Centre, Medical University of Vienna

Career Start Year 2002

Number of shared co-authors 1

Ga??lle Legube

CNRS, Universite de Toulouse

Career Start Year 2002

Number of shared co-authors 3

Kyle M Miller

The University of Texas at Austin

Career Start Year 2001

Number of shared co-authors 2

Haico van Attikum

Leiden University Medical Center

Career Start Year 2001

Number of shared co-authors 2

Tarek Abbas

University of Virginia

Career Start Year 2001

Number of shared co-authors 0

Junjie Chen

The University of Texas MD Anderson Cancer Center

Career Start Year 2000

Number of shared co-authors 0

Thomas Helleday

The University of Sheffield

Career Start Year 1998

Number of shared co-authors 3

Aaron Aslanian

Salk Institute for Biological Studies

Career Start Year 1998

Number of shared co-authors 0

Marcus B Smolka

Weill Institute for Cell and Molecular Biology, Cornell University

Career Start Year 1998

Number of shared co-authors 0

Kenji Shimada

Friedrich Miescher Institute for Biomedical Research

Career Start Year 1997

Number of shared co-authors 0

Simon J Boulton

The Francis Crick Institute

Career Start Year 1996

Number of shared co-authors 3

Shiaw-Yih Lin

The University of Texas MD Anderson Cancer Center

Career Start Year 1996

Number of shared co-authors 0

Christopher J Bakkenist

UPMC Hillman Cancer Center, University of Pittsburgh

Career Start Year 1994

Number of shared co-authors 0

Grant W Brown

University of Toronto, 1 King's College Circle

Career Start Year 1991

Number of shared co-authors 2

David P Toczyski

University of California San Francisco

Career Start Year 1991

Number of shared co-authors 1

Peter D Adams

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1991

Number of shared co-authors 0

Mirit I Aladjem

National Cancer Institute, Center for Cancer Research

Career Start Year 1988

Number of shared co-authors 0

Tanya T Paull

University of Texas at Austin

Career Start Year 1988

Number of shared co-authors 3

Jean Gautier

Institute of Cancer Genetics, Columbia University Irving Medical Center

Career Start Year 1983

Number of shared co-authors 0

Ashok R Venkitaraman

University of Cambridge, Hutchison Research Centre

Career Start Year 1982

Number of shared co-authors 0

Susan M Gasser

L'Institut Suisse de Recherche Experimentale sur le Cancer (ISREC) Foundation

Career Start Year 1982

Number of shared co-authors 1

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Career Start Year 1982

Number of shared co-authors 1

row(s) 1 - 30 of 30

Beate Neumann

Center for Molecular Materials, Universitat Bielefeld, Universitatsstrasse 25

Co-authored papers 4

Stephen P Jackson

Mission Therapeutics Ltd. Glenn Berge Building

Co-authored papers 3

Jean-Karim H??rich??

University of California san francisco

Co-authored papers 3

Rainer Pepperkok

Translational Lung Research Center Heidelberg, German Center for Lung Research

Co-authored papers 3

Jan Ellenberg

Institute of Child Health and Human Development

Co-authored papers 3

Patrice Menard

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Co-authored papers 2

Dipanjan Chowdhury

Dana-Farber Cancer Institute

Co-authored papers 2

Jahn M Nesland

The Norwegian Radium Hospital, Oslo University Hospital

Co-authored papers 1

Fabian Coscia

Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)

Co-authored papers 1

Alberto Santos

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Co-authored papers 1

Lise Mette Rahbek-Gjerdrum

Zealand University Hospital

Co-authored papers 1

Andr??s Kriston

Biological Research Centre

Co-authored papers 1

Jens S Andersen

University of Southern Denmark

Co-authored papers 1

Christian Gnann

KTH-Royal Institute of Technology

Co-authored papers 1

Matthias Mann

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Co-authored papers 1

Ferenc Kov??cs

Biological Research Centre

Co-authored papers 1

Florian Huber

Co-authored papers 1

Beatrice Dyring-Andersen

Herlev and Gentofte Hospital, University of Copenhagen

Co-authored papers 1

Soraya Naimy

Zealand University Hospital

Co-authored papers 1

Peter K Jackson

Stanford University School of Medicine, Center for Clinical Sciences Research

Co-authored papers 1

Mark A Eckert

Medical University of South Carolina

Co-authored papers 1

Daniel Durocher

The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital

Co-authored papers 1

Andreas-David Brunner

Max-Planck Institute of Biochemistry

Co-authored papers 1

Michael Bzorek

Zealand University Hospital

Co-authored papers 1

Peter Horvath

Institute of Biochemistry, Biological Research Centre

Co-authored papers 1

Sofie V Nielsen

University of Copenhagen

Co-authored papers 1

Chunaram Choudhary

The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Co-authored papers 1

Ernst Lengyel

University of Chicago

Co-authored papers 1

Erich A Nigg

University of Basel

Co-authored papers 1

Andreas Mund

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Co-authored papers 1

1 - 30

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