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Author Details

Martine Therrien
2004
18
9
PMIDPaper TitleJournal TitlePublished Year
37500887Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.Nat Immunol2023
37774681Early Alzheimer's disease pathology in human cortex involves transient cell states.2023
37333365Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states.2023
37075753FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.Cell Metab2023
36865221FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.bioRxiv2023
36155944Redefining microglia states: Lessons and limits of human and mouse models to study microglia states in neurodegenerative diseases.Seminars in Immunology2022
32681824Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.Neuron2020
30378261Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.Am J Med Genet B Neuropsychiatr Genet2019
28910613Resolving CNS mRNA Heterogeneity: Examining mRNA Alternative Polyadenylation at a Cell-Type-Specific Level.Neuron2017
27071850Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).Journal of Agricultural and Food Chemistry2016
27113253ALS: Recent Developments from Genetics Studies.Curr Neurol Neurosci Rep2016
27117089FET proteins regulate lifespan and neuronal integrity.Sci Rep2016
25254150Deciphering genetic interactions between ALS genes using C. elegans.2014
24860590Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans.Frontiers in Genetics2014
24349511Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans.PLoS One2013
22337953Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models.Hum Mol Genet2012
22848727Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.PLoS ONE2012
15231574Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a Children's Oncology Group phase 1 study.Blood2004
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Broad Institute of MIT and Harvard
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Massachusetts Institute of Technology, USA Broad Institute
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