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Author Details

Sonia Zu??iga
Campus Universidad Autonoma de Madrid
1999
49
23
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36602354Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin.Antimicrob Agents Chemother2023
37942479Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis.Front Cell Infect Microbiol2023
37607224SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice.Proc Natl Acad Sci U S A2023
36992394Efficient CRISPR-Cas13d-Based Antiviral Strategy to Combat SARS-CoV-2.Viruses2023
37206325Dextran sulfate from <i>Leuconostoc mesenteroides</i> B512F exerts potent antiviral activity against SARS-CoV-2 <i>in vitro</i> and <i>in vivo</i>.Front Microbiol2023
37066301SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice.bioRxiv2023
34851142Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 Laboratories.J Virol2022
35966177Nature of viruses and pandemics: Coronaviruses.Curr Res Immunol2022
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
35314834Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19.Nature2022
33144319Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.J Virol2021
33653888Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection.mBio2021
33929101A multiplex antigen microarray for simultaneous IgG and IgM detection against SARS-CoV-2 reveals higher seroprevalence than reported.Microb Biotechnol2021
34517762MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity.mBio2021
34686605Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice.Proc Natl Acad Sci U S A2021
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
31349683Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV.Viruses2019
31861369Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein.Pathogens2019
27009949Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.J Virol2016
27712626Molecular Basis of Coronavirus Virulence and Vaccine Development.Adv Virus Res2016
27397100Virulence factors in porcine coronaviruses and vaccine design.Virus Res2016
25759500Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response.mBio2015
26958916Continuous and Discontinuous RNA Synthesis in Coronaviruses.Annu Rev Virol2015
24930446Coronavirus reverse genetic systems: infectious clones and replicons.Virus Res2014
25261606Reprint of: Coronavirus reverse genetic systems: infectious clones and replicons.Virus Res2014
25108114Antigenic structures stably expressed by recombinant TGEV-derived vectors.Virology2014
23055566Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription.J Virol2013
23824792Alphacoronavirus protein 7 modulates host innate immune response.J Virol2013
24023385Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate.mBio2013
23394559The use of transient expression systems for the rapid production of virus-like particles in plants.Curr Pharm Des2013
21411518The polypyrimidine tract-binding protein affects coronavirus RNA accumulation levels and relocalizes viral RNAs to novel cytoplasmic domains different from replication-transcription sites.J Virol2011
21715479Gene N proximal and distal RNA motifs regulate coronavirus nucleocapsid mRNA transcription.J Virol2011
21695242Coronavirus gene 7 counteracts host defenses and modulates virus virulence.PLoS Pathog2011
21378501RNA-RNA and RNA-protein interactions in coronavirus replication and transcription.RNA Biol2011
19955314Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription.J Virol2010
20600388Vectored vaccines to protect against PRRSV.Virus Res2010
18675859Role of RNA chaperones in virus replication.Virus Res2009
18272586Identification of a coronavirus transcription enhancer.J Virol2008
16979208Coronavirus nucleocapsid protein is an RNA chaperone.Virology2007
16928748Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.J Virol2006
17037500Regulation of coronavirus transcription: viral and cellular proteins interacting with transcription-regulating sequences.Adv Exp Med Biol2006
17037498Biochemical aspects of coronavirus replication.Adv Exp Med Biol2006
16712436Biochemical aspects of coronavirus replication and virus-host interaction.Annu Rev Microbiol2006
15681451Role of nucleotides immediately flanking the transcription-regulating sequence core in coronavirus subgenomic mRNA synthesis.J Virol2005
15609512Coronavirus reverse genetics and development of vectors for gene expression.Curr Top Microbiol Immunol2005
14694129Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis.J Virol2004
12634392Engineering the transmissible gastroenteritis virus genome as an expression vector inducing lactogenic immunity.J Virol2003
10375630Deletion of 24 open reading frames from chromosome XI from Saccharomyces cerevisiae and phenotypic analysis of the deletants.Gene1999
10407274Disruption of six Saccharomyces cerevisiae novel genes and phenotypic analysis of the deletants.Yeast1999
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Collaborators

Luis Enjuanes
Campus Universidad Autonoma de Madrid
Co-authored papers 47
Isabel Sola
Campus Universidad Autonoma de Madrid
Co-authored papers 40
Javier G??mez
Hospital Universitario Marques de Valdecilla
Co-authored papers 2
Jose A Lopez-Martin
Hospital Universitario 12 de Octubre
Co-authored papers 2
Noemi Cabello
Centro Sandoval and Hospital Universitario Clinico de San Carlos
Co-authored papers 2
Jos?? Barber??n
Hospital Universitario HM Monteprincipe, HM Hospitales
Co-authored papers 2
Greg J Towers
University College London
Co-authored papers 2
Beatriz de Rivas
University of the Basque Country UPV/EHU
Co-authored papers 2
Pablo Avil??s
Departamento de Toxicologia y Farmacologia Preclinica
Co-authored papers 2
Rubin Lubomirov
Clinical Development
Co-authored papers 2
Kirsten Obernier (CM4AI)
University of California San Francisco
Co-authored papers 2
Nuria Izquierdo-Useros
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Jose F Varona
Hospital Universitario HM Monteprincipe, HM Hospitales
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Jordi Rodon
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Salvador Fudio
Clinical Development
Co-authored papers 2
Soner Yildiz
University of Geneva
Co-authored papers 2
Julio Ancochea
Instituto de Salud Carlos III, Hospital Universitario La Princesa
Co-authored papers 2
Roger Paredes
Hospital Germans Trias i Pujol
Co-authored papers 2
Daniel Carnevali-Ruiz
Hospital Universitario Quironsalud Madrid
Co-authored papers 2
Antonio Nieto
Clinical R&D
Co-authored papers 2
Bonaventura Clotet
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Roberto Vates
Hospital Universitario de Getafe
Co-authored papers 2
Lucy Thorne
University College London
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
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Daniel Abad
Universidad Europea
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Pedro Landete
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Maria J S L Pontes
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