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Author Details

Karen H Martin
West Virginia University Cancer Institute, West Virginia University
1993
53
25
PMIDPaper TitleJournal TitlePublished Year
36765664Chemotherapeutic Activity of Pitavastatin in Vincristine Resistant B-Cell Acute Lymphoblastic Leukemia.Cancers (Basel)2023
35681662Pitavastatin Is Anti-Leukemic in a Bone Marrow Microenvironment Model of B-Lineage Acute Lymphoblastic Leukemia.Cancers (Basel)2022
34349149Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease.Sci Rep2021
34496224Loss of the redox mitochondrial protein mitoNEET leads to mitochondrial dysfunction in B-cell acute lymphoblastic leukemia.Free Radic Biol Med2021
32586284Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.BMC Cancer2020
31989336Pyrvinium Pamoate Use in a B cell Acute Lymphoblastic Leukemia Model of the Bone Tumor Microenvironment.Pharm Res2020
31010844The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia.J Pharmacol Exp Ther2019
28259153Altering calcium influx for selective destruction of breast tumor.BMC Cancer2017
26891147Modeling Chemotherapy Resistant Leukemia In Vitro.J Vis Exp2016
26407636Bone marrow microenvironment modulation of acute lymphoblastic leukemia phenotype.Exp Hematol2016
25632159SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.J Cell Sci2015
26488876Three-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic Leukemia.PLoS One2015
26408544Leptin decreases heart rate associated with increased ventricular repolarization via its receptor.Am J Physiol Heart Circ Physiol2015
26770884Modeling The Bone Marrow Microenvironment's Influence on Leukemic Disease.Transl Biomed2015
26132316High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer.Cancers (Basel)2015
25658311PP2 prevents isoproterenol stimulation of cardiac pacemaker activity.J Cardiovasc Pharmacol2015
24566462PP2 prevents β-adrenergic stimulation of cardiac pacemaker activity.J Cardiovasc Pharmacol2014
24873662Induction of stemlike cells with fibrogenic properties by carbon nanotubes and its role in fibrogenesis.Nano Lett2014
24855276RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expression.Stem Cells Transl Med2014
23146907Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop.Oncogene2013
24143275Metastatic MTLn3 and non-metastatic MTC adenocarcinoma cells can be differentiated by Pseudomonas aeruginosa.Biol Open2013
23218908High-resolution vascular tissue characterization in mice using 55MHz ultrasound hybrid imaging.Ultrasonics2013
23217101The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue.Mol Microbiol2013
22363485Bone marrow osteoblast damage by chemotherapeutic agents.PLoS One2012
22952016Quantitative measurement of invadopodia-mediated extracellular matrix proteolysis in single and multicellular contexts.J Vis Exp2012
23097045Src binds cortactin through an SH2 domain cystine-mediated linkage.J Cell Sci2012
22689823Examining the role of actin-plasma membrane association in Pseudomonas aeruginosa infection and type III secretion translocation in migratory T24 epithelial cells.Infect Immun2012
20839232The role of calcium release activated calcium channels in osteoclast differentiation.J Cell Physiol2011
22168784The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group A Streptococcus.BMC Microbiol2011
21866257Further insights into cortactin conformational regulation.Bioarchitecture2011
21808230Multi-photon imaging of tumor cell invasion in an orthotopic mouse model of oral squamous cell carcinoma.J Vis Exp2011
21655441Revisiting the ERK/Src cortactin switch.Commun Integr Biol2011
20300619Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway.PLoS One2010
21079800Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence.PLoS One2010
21209775VE-cadherin Regulates Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Sensitivity to Apoptosis.Cancer Microenviron2010
20980387Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.J Cell Sci2010
20164379Inactivation of L-type calcium channel modulated by HCN2 channel.Am J Physiol Cell Physiol2010
19592614A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells.Am J Physiol Heart Circ Physiol2009
20505783Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function.J Cancer Sci Ther2009
18303050FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.J Cell Sci2008
17395594Cellular characterization of a novel focal adhesion kinase inhibitor.J Biol Chem2007
17440961Disruption of FRNK expression by gene targeting of the intronic promoter within the focal adhesion kinase gene.J Cell Biochem2007
16825425Cortactin phosphorylation sites mapped by mass spectrometry.J Cell Sci2006
15914540Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells.J Cell Sci2005
16254240FAK phosphorylation sites mapped by mass spectrometry.J Cell Sci2005
11921165Regulation of focal adhesion targeting and inhibitory functions of the FAK related protein FRNK using a novel estrogen receptor "switch".Cell Motil Cytoskeleton2002
12058076The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly.Mol Biol Cell2002
12040184Integrin connections map: to infinity and beyond.Science2002
11114741Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement.Oncogene2000
10392723Novel acylation of poxvirus A-type inclusion proteins.Virus Res1999
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Collaborators

John T Parsons
The School of Medicine, University of Virginia
Co-authored papers 10
Robert W Tilghman
University of Virginia
Co-authored papers 3
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 2
Donald F Hunt
University of Virginia
Co-authored papers 2
Pablo R Grigera
Instituto de Ciencia y Tecnologia Dr. Cesar Milstein
Co-authored papers 2
Jeffrey Shabanowitz
University of Virginia
Co-authored papers 2
Peter A Humphrey
Yale University School of Medicine
Co-authored papers 1
Peggi M Angel
Co-authored papers 1
Release 1.2