Author details

Full Name

Chris A Kaiser

Affiliation

Massachusetts Institute of Technology

ORCID

Career Start Year

1986

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
30451826	Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.	Nat Commun	2018
26837754	Chromosome-Specific and Global Effects of Aneuploidy in Saccharomyces cerevisiae.	Genetics	2016
24723613	Mapping the cellular response to small molecules using chemogenomic fitness signatures.	Science	2014
25053742	Redox signaling via the molecular chaperone BiP protects cells against endoplasmic reticulum-derived oxidative stress.	Elife	2014
22412017	Balanced Ero1 activation and inactivation establishes ER redox homeostasis.	J Cell Biol	2012
21471002	Transport activity-dependent intracellular sorting of the yeast general amino acid permease.	Mol Biol Cell	2011
20093466	The genetic landscape of a cell.	Science	2010
20655927	Structural conservation of components in the amino acid sensing branch of the TOR pathway in yeast and mammals.	J Mol Biol	2010
20348090	Oxidative activity of yeast Ero1p on protein disulfide isomerase and related oxidoreductases of the endoplasmic reticulum.	J Biol Chem	2010
18191641	Ero1 and redox homeostasis in the endoplasmic reticulum.	Biochim Biophys Acta	2008
18845159	Yeast Mpd1p reveals the structural diversity of the protein disulfide isomerase family.	J Mol Biol	2008
18434603	Different ubiquitin signals act at the Golgi and plasma membrane to direct GAP1 trafficking.	Mol Biol Cell	2008
17448992	Modulation of cellular disulfide-bond formation and the ER redox environment by feedback regulation of Ero1.	Cell	2007
16641373	Amino acids regulate retrieval of the yeast general amino acid permease from the vacuolar targeting pathway.	Mol Biol Cell	2006
16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.	Nat Cell Biol	2006
16771671	Conservation and diversity of the cellular disulfide bond formation pathways.	Antioxid Redox Signal	2006
16893552	Gain of function in an ERV/ALR sulfhydryl oxidase by molecular engineering of the shuttle disulfide.	J Mol Biol	2006
16885415	Activity-dependent reversible inactivation of the general amino acid permease.	Mol Biol Cell	2006
16407158	Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p.	Proc Natl Acad Sci U S A	2006
16495342	Disulfide transfer between two conserved cysteine pairs imparts selectivity to protein oxidation by Ero1.	Mol Biol Cell	2006
15930008	The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases.	Protein Sci	2005
16288914	Structural determinants of substrate access to the disulfide oxidase Erv2p.	J Mol Biol	2005
15163408	Structure of Ero1p, source of disulfide bonds for oxidative protein folding in the cell.	Cell	2004
15242642	Exploration of essential gene functions via titratable promoter alleles.	Cell	2004
12719473	LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway.	J Cell Biol	2003
11740506	A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.	Nat Struct Biol	2002
12417748	Amino acids regulate the intracellular trafficking of the general amino acid permease of Saccharomycescerevisiae.	Proc Natl Acad Sci U S A	2002
12415301	Formation and transfer of disulphide bonds in living cells.	Nat Rev Mol Cell Biol	2002
12062797	Nitrogen regulation in Saccharomyces cerevisiae.	Gene	2002
12006647	Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p.	Mol Biol Cell	2002
12073353	Subcellular fractionation of secretory organelles.	Methods Enzymol	2002
11584268	A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation.	Nat Cell Biol	2001
11352928	Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.	J Cell Biol	2001
10754564	Pathways for protein disulphide bond formation.	Trends Cell Biol	2000
10982384	Two pairs of conserved cysteines are required for the oxidative activity of Ero1p in protein disulfide bond formation in the endoplasmic reticulum.	Mol Biol Cell	2000
10923020	Isolation of Pichia pastoris genes involved in ER-to-Golgi transport.	Yeast	2000
10760248	Thinking about p24 proteins and how transport vesicles select their cargo.	Proc Natl Acad Sci U S A	2000
10712514	Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.	Mol Biol Cell	2000
10559898	Competition between glutathione and protein thiols for disulphide-bond formation.	Nat Cell Biol	1999
10330397	LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum.	J Cell Biol	1999
10549279	Ero1p oxidizes protein disulfide isomerase in a pathway for disulfide bond formation in the endoplasmic reticulum.	Mol Cell	1999
10574704	Identification of the putative mammalian orthologue of Sec31P, a component of the COPII coat.	J Cell Sci	1999
9719868	Transport from the endoplasmic reticulum to the Golgi.	Curr Opin Cell Biol	1998
9659913	The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum.	Mol Cell	1998
9819400	A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1.	Mol Cell Biol	1998
9409822	Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.	Genetics	1997
9199164	Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae.	J Cell Biol	1997
9325247	COPII subunit interactions in the assembly of the vesicle coat.	J Biol Chem	1997
8862519	Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.	Mol Biol Cell	1996
8909538	A pathway for targeting soluble misfolded proteins to the yeast vacuole.	J Cell Biol	1996

1 - 50 of 64

Aeid Igbaria

Inserm U2, University of Rennes

Career Start Year 2007

Number of shared co-authors 1

Florian Fr??hlich

Osnabruck University Department of Biology/Chemistry Bioanalytical Chemistry section

Career Start Year 2007

Number of shared co-authors 1

Vladimir Denic

Harvard University

Career Start Year 2005

Number of shared co-authors 4

Franklin A Hays

University of Oklahoma Health Sciences Center

Career Start Year 2003

Number of shared co-authors 0

Michael Davey

BC Children's Hospital Research Institute, University of British Columbia

Career Start Year 2000

Number of shared co-authors 9

Allyson F O'Donnell

University of Pittsburgh

Career Start Year 2000

Number of shared co-authors 0

Maya Schuldiner

The Weizmann Institute of Science

Career Start Year 2000

Number of shared co-authors 8

Pablo S Aguilar

Instituto de Fisiologia

Career Start Year 1998

Number of shared co-authors 1

Jean-Claude Farr??

University of California

Career Start Year 1998

Number of shared co-authors 0

Ashkan Golshani

Ottawa Institute of Systems Biology, Carleton University

Career Start Year 1997

Number of shared co-authors 10

Liesbeth M Veenhoff

European Institute for the Biology of Ageing, University of Groningen

Career Start Year 1996

Number of shared co-authors 0

V??ronique Alban??se

Universite Paris Cite, CNRS, Institut Jacques Monod

Career Start Year 1996

Number of shared co-authors 1

Marcello Marelli

AstraZeneca Oncology R&D

Career Start Year 1995

Number of shared co-authors 1

Christopher J Stefan

University College London

Career Start Year 1991

Number of shared co-authors 1

Jonathan S Weissman

Whitehead Institute for Biomedical Research

Career Start Year 1991

Number of shared co-authors 10

Won-Ki Huh

Seoul National University

Career Start Year 1991

Number of shared co-authors 3

Christopher G Burd

Yale School of Medicine

Career Start Year 1989

Number of shared co-authors 16

Eric G D Muller

University of Washington

Career Start Year 1989

Number of shared co-authors 1

John D Aitchison

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Career Start Year 1988

Number of shared co-authors 1

Ineke Braakman

Utrecht University

Career Start Year 1987

Number of shared co-authors 0

Stanley Fields

University of Washington

Career Start Year 1985

Number of shared co-authors 8

Helena Friesen

University of Toronto

Career Start Year 1984

Number of shared co-authors 22

Sean Munro

Medical Research Council Laboratory of Molecular Biology

Career Start Year 1984

Number of shared co-authors 16

Richard A Rachubinski

University of Alberta

Career Start Year 1980

Number of shared co-authors 3

Randolph Y Hampton

University of California San Diego

Career Start Year 1980

Number of shared co-authors 2

Pamela A Silver

Harvard Medical School

Career Start Year 1979

Number of shared co-authors 2

Scott D Emr

Weill Institute for Cell and Molecular Biology, Cornell University

Career Start Year 1978

Number of shared co-authors 2

Peter Walter

University of California san francisco

Career Start Year 1977

Number of shared co-authors 1

Stephen G Oliver

University of Cambridge

Career Start Year 1976

Number of shared co-authors 7

Suresh Subramani

University of California San Diego

Career Start Year 1975

Number of shared co-authors 0

row(s) 1 - 30 of 30

Peter J Espenshade

Johns Hopkins University School of Medicine

Co-authored papers 5

David Botstein

Calico Life Sciences LLC

Co-authored papers 4

Charles Boone

University of Toronto

Co-authored papers 3

Michael Costanzo

Co-authored papers 2

Gary D Bader

University of Toronto

Co-authored papers 2

Zhijian Li

University of Toronto

Co-authored papers 2

Iain M Wallace

Novartis Institutes for BioMedical Research

Co-authored papers 2

Darcy L Morse

Massachusetts Institute of Technology

Co-authored papers 2

Quaid Morris

Sloan Kettering Institute

Co-authored papers 2

Brenda J Andrews

University of Toronto

Co-authored papers 2

Jennifer Haynes

Joan C. Edwards School of Medicine, Marshall University

Co-authored papers 1

Renee L Brost

Cubist Pharmaceuticals, Inc.

Co-authored papers 1

Vincent C Tam

Temple University

Co-authored papers 1

Wen-Tao Peng

West China Second University Hospital, Sichuan University

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Sara Mostafavi

University of British Columbia and BC Children's Hospital

Co-authored papers 1

Marcela Gronda

Princess Margaret Cancer Centre

Co-authored papers 1

Andres Lopez

Universidad de Valparaiso

Co-authored papers 1

Anna Y Lee

Ontario Institute for Cancer Research

Co-authored papers 1

Matthew T Weirauch

University of Cincinnati College of Medicine

Co-authored papers 1

Lawrence E Heisler

Ontario Institute for Cancer Research

Co-authored papers 1

Olga G Troyanskaya

Lewis-Sigler Institute for Integrative Genomics, Princeton University

Co-authored papers 1

Anne-Claude Gingras

Lunenfeld-Tanenbaum Research Institute

Co-authored papers 1

Alan R Davidson

University of Toronto, University Avenue

Co-authored papers 1

Shawna L Hiley

University of Toronto College Street

Co-authored papers 1

Anand Swaroop

National Eye Institute, National Institutes of Health

Co-authored papers 1

Miles Trochesset

Co-authored papers 1

Michael Brudno

University of Toronto

Co-authored papers 1

Jie Wang

Co-authored papers 1

Sanie Mnaimneh

University of Toronto

Co-authored papers 1

1 - 30

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