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Author Details

Anna Lasorella
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
1984
103
47
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36732634Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy.Nat Cancer2023
37770427Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures.Nat Commun2023
36445254LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.Cancer Discov2023
35914528Glioblastoma hijacks neuronal mechanisms for brain invasion.Cell2022
35440621Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription.Nat Commun2022
35969037Tissue-specific modifier alleles determine <i>Mertk</i> loss-of-function traits.Elife2022
34031428Anti-tumor effects of an ID antagonist with no observed acquired resistance.NPJ Breast Cancer2021
33767415The making of the glioblastoma classification.Br J Cancer2021
33681822Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities.Nat Cancer2021
34699786Inhibition of ERK/MAPK signaling as potential therapy to prevent optic pathway glioma in infants with neurofibromatosis type 1.Dev Cell2021
34011400Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker.Genome Med2021
32413119Clinical, molecular, and radiomic profile of gliomas with FGFR3-TACC3 fusions.Neuro Oncol2020
33155039A map of tumor-host interactions in glioma at single-cell resolution.Gigascience2020
33173156Integrating single-cell RNA-seq and imaging with SCOPE-seq2.Sci Rep2020
32640193Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation.Mol Cell2020
30531922The molecular landscape of glioma in patients with Neurofibromatosis 1.Nat Med2019
31577956A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.Cell Rep2019
31044160The combination of neoantigen quality and T lymphocyte infiltrates identifies glioblastomas with the longest survival.Commun Biol2019
30796088De novo gene signature identification from single-cell RNA-seq with hierarchical Poisson factorization.Mol Syst Biol2019
28976058Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features.Brain Pathol2018
29915258A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.Nat Commun2018
30041684Single-cell transcriptome analysis of lineage diversity in high-grade glioma.Genome Med2018
29703840Transcription factor ID2 prevents E proteins from enforcing a naïve T lymphocyte gene program during NK cell development.Sci Immunol2018
29361062RGBM: regularized gradient boosting machines for identification of the transcriptional regulators of discrete glioma subtypes.Nucleic Acids Res2018
29510988Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.Cancer Discov2018
29323298A metabolic function of FGFR3-TACC3 gene fusions in cancer.Nature2018
28003334HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.EMBO Mol Med2017
28938460Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response.Endocrinology2017
29092923Novel <i>SEC61G</i>-<i>EGFR</i> Fusion Gene in Pediatric Ependymomas Discovered by Clonal Expansion of Stem Cells in Absence of Exogenous Mitogens.Cancer Res2017
28687618Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-<i>H19</i> Cascade.Cancer Res2017
27852792FGFR-TACC gene fusions in human glioma.Neuro Oncol2017
26735018An ID2-dependent mechanism for VHL inactivation in cancer.Nature2016
27668798The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.Nat Immunol2016
27270107Clonal evolution of glioblastoma under therapy.Nat Genet2016
27213691Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation.Nat Immunol2016
26880074Id2 regulates hyporesponsive invariant natural killer T cells.Immunol Cell Biol2016
25609060Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma.Clin Cancer Res2015
25902484Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota.Immunity2015
24442143The ID proteins: master regulators of cancer stem cells and tumour aggressiveness.Nat Rev Cancer2014
24980046ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2.J Exp Med2014
25183062Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer.BMC Syst Biol2014
24960692Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.Dev Cell2014
24614276Myc and differentiation: going against the current.EMBO Rep2014
23241957Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.J Clin Invest2013
24244015Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.J Immunol2013
23917401The integrated landscape of driver genomic alterations in glioblastoma.Nat Genet2013
23774217RHPN2 drives mesenchymal transformation in malignant glioma by triggering RhoA activation.Cancer Res2013
22425249E protein transcription factors are required for the development of CD4(+) lineage T cells.Immunity2012
22745378Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis.J Immunol2012
22837387Transforming fusions of FGFR and TACC genes in human glioblastoma.Science2012
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Collaborators

Antonio Iavarone
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 75
Marc Sanson
Co-authored papers 9
Veronique Frattini
Institute for Cancer Genetics, Columbia University Medical Center
Co-authored papers 9
Michele Ceccarelli
Co-authored papers 9
Karima Mokhtari
Co-authored papers 7
Gaetano Finocchiaro
IRCCS San Raffaele Scientific Institute
Co-authored papers 5
Raul Rabadan
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 5
Marica Eoli
Fondazione IRCCS Istituto Neurologico Carlo Besta
Co-authored papers 5
Kenneth Aldape
National Cancer Institute
Co-authored papers 5
Timothy Cardozo
Co-authored papers 4
Andrea Califano
Columbia University
Co-authored papers 4
Rajesh K Soni
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 3
Francesco Abate
Columbia University
Co-authored papers 3
Do-Hyun Nam
Samsung Medical Center, Sungkyunkwan University School
Co-authored papers 3
Mikael Sigvardsson
Lund University, Linkoping University. .
Co-authored papers 2
Mario L Suv??
Broad Institute of MIT and Harvard
Co-authored papers 2
Wei Keat Lim
Regeneron Pharmaceuticals
Co-authored papers 2
Erik P Sulman
NYU Grossman School of Medicine
Co-authored papers 2
Ronald C Hendrickson
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Fuchou Tang
College of Life Sciences
Co-authored papers 2
Larry Norton
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Andrew J Dannenberg
Co-authored papers 2
Mariano J Alvarez
Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center
Co-authored papers 2
Dominique Figarella-Branger
Co-authored papers 2
Sakellarios Zairis
Columbia University
Co-authored papers 2
Tom Mikkelsen
Ontario Brain Institute
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Fran??ois Guillemot
the Francis Crick Institute
Co-authored papers 2
Harmen J Bussemaker
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Thais S Sabedot
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