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Author Details

Niall J Lennon
Broad Institute of MIT and Harvard.
1997
80
38
PMIDPaper TitleJournal TitlePublished Year
36621880Returning integrated genomic risk and clinical recommendations: The eMERGE study.Genet Med2023
37790445Genetic Sex Validation for Sample Tracking in Clinical Testing.Res Sq2023
34793200Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation.J Clin Oncol2022
35710995Genome-wide polygenic score to predict chronic kidney disease across ancestries.Nat Med2022
35739269Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.Nat Med2022
35346344Whole-genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the All of Us Research Program.Genome Med2022
35765100Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.Genome Med2022
35446370Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases.JAMA Oncol2022
36215125Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer.Clin Cancer Res2022
35033226Durvalumab plus tremelimumab alone or in combination with low-dose or hypofractionated radiotherapy in metastatic non-small-cell lung cancer refractory to previous PD(L)-1 therapy: an open-label, multicentre, randomised, phase 2 trial.Lancet Oncol2022
35051367Transmission from vaccinated individuals in a large SARS-CoV-2 Delta variant outbreak.Cell2022
35022065Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome.Genome Biol2022
34191585Implementation of SARS-CoV2 Screening in K-12 Schools Using In-School Pooled Molecular Testing and Deconvolution by Rapid Antigen Test.J Clin Microbiol2021
33622768Performance and Implementation Evaluation of the Abbott BinaxNOW Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts.J Clin Microbiol2021
33594381Estimating epidemiologic dynamics from cross-sectional viral load distributions.medRxiv2021
34976934Pooling for SARS-CoV2 Surveillance: Validation and Strategy for Implementation in K-12 Schools.Front Public Health2021
34704102Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts.medRxiv2021
34598685Design and user experience testing of a polygenic score report: a qualitative study of prospective users.BMC Med Genomics2021
34250188Performance and Operational Evaluation of the Access Bio CareStart Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts.Open Forum Infect Dis2021
34016182Modeling clonal structure over narrow time frames via circulating tumor DNA in metastatic breast cancer.Genome Med2021
34098564Plasma Mucin-1 (CA15-3) Levels in Autosomal Dominant Tubulointerstitial Kidney Disease due to MUC1 Mutations.Am J Nephrol2021
34083451Estimating epidemiologic dynamics from cross-sectional viral load distributions.Science2021
34255846Cross-Sectional Assessment of SARS-CoV-2 Viral Load by Symptom Status in Massachusetts Congregate Living Facilities.J Infect Dis2021
32170028Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer.Clin Cancer Res2020
33110627Best practices for the analytical validation of clinical whole-genome sequencing intended for the diagnosis of germline disease.NPJ Genom Med2020
30568305Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.Nature2019
29739332Characterization and remediation of sample index swaps by non-redundant dual indexing on massively parallel sequencing platforms.BMC Genomics2018
29941871DeTiN: overcoming tumor-in-normal contamination.Nat Methods2018
29542692Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma.Nature2018
28678778An immunogenic personal neoantigen vaccine for patients with melanoma.Nature2017
27157321Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease.J Mol Diagn2016
27736792Accurate Estimation of Fungal Diversity and Abundance through Improved Lineage-Specific Primers Optimized for Illumina Amplicon Sequencing.Appl Environ Microbiol2016
27784341Technological considerations for genome-guided diagnosis and management of cancer.Genome Med2016
27163788Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.PLoS Pathog2016
25673644Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.Cancer Discov2015
26488565Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.N Engl J Med2015
26276630Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.Cell2015
24658644The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells.Nat Biotechnol2014
24689939Rich and cold: diversity, distribution and drivers of fungal communities in patterned-ground ecosystems of the North American Arctic.Mol Ecol2014
21757030Genetic diversity and lineage dynamic of dengue virus serotype 1 (DENV-1) in Cambodia.Infect Genet Evol2013
24157732Semiconductor-based DNA sequencing of histone modification states.Nat Commun2013
24185511Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.Nat Genet2013
23718773Characterizing and measuring bias in sequence data.Genome Biol2013
23136221Whole genome pyrosequencing of rare hepatitis C virus genotypes enhances subtype classification and identification of naturally occurring drug resistance variants.J Infect Dis2013
22677620Complex dynamic of dengue virus serotypes 2 and 3 in Cambodia following series of climate disasters.Infect Genet Evol2013
22090119High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.J Virol2012
22974120De novo assembly of highly diverse viral populations.BMC Genomics2012
22718199Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans.Hum Mol Genet2012
22740715Reemergence and decline of dengue virus serotype 3 in Puerto Rico.J Infect Dis2012
22820256Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.Nature2012
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Collaborators

Matthew R Henn
Co-authored papers 23
Bruce W Birren
Broad Institute of MIT and Harvard
Co-authored papers 19
Chad Nusbaum
Co-authored papers 9
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 9
Michael C Zody
Broad Institute of Harvard and MIT
Co-authored papers 8
Eric S Lander
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 8
Stacey Gabriel
Broad Institute of MIT and Harvard
Co-authored papers 7
Todd M Allen
Co-authored papers 7
Maegan Harden
Broad Institute of MIT and Harvard.
Co-authored papers 7
Brendan Blumenstiel
Broad Institute of MIT and Harvard
Co-authored papers 6
Carsten Russ
Co-authored papers 6
Catherine J Wu
Co-authored papers 5
Heidi L Rehm
The Broad Institute of MIT and Harvard
Co-authored papers 5
Jonna Grimsby
Co-authored papers 5
Gail P Jarvik
University of Washington Medical Center
Co-authored papers 5
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 4
Jerome Ritz
Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital
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Matthew DeFelice
Broad Institute of Harvard and MIT
Co-authored papers 4
David B Jaffe
Co-authored papers 4
Donna Neuberg
Co-authored papers 4
Bruce D Walker
Ragon Institute of Mass General
Co-authored papers 4
Manuel Garber
Co-authored papers 4
Edward C Holmes
Sydney Institute for Infectious Diseases, The University of Sydney
Co-authored papers 3
James Bochicchio
Co-authored papers 3
Iftikhar J Kullo
Mayo Clinic
Co-authored papers 3
Jordan W Smoller
Center for Genomic Medicine, Massachusetts General Hospital
Co-authored papers 3
Andrew Zimmer
Co-authored papers 3
Matthew Meyerson
Broad Institute
Co-authored papers 3
Elizabeth W Karlson
Brigham and Women's Hospital
Co-authored papers 3
Daniel J Park
Broad Institute of MIT and Harvard
Co-authored papers 3
Release 1.2